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Journal Abstract Search

256 related items for PubMed ID: 31004594

  • 1. Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes.
    Zorbaz T, Malinak D, Kuca K, Musilek K, Kovarik Z.
    Chem Biol Interact; 2019 Jul 01; 307():16-20. PubMed ID: 31004594
    [Abstract] [Full Text] [Related]

  • 2. Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents.
    Zorbaz T, Malinak D, Maraković N, Maček Hrvat N, Zandona A, Novotny M, Skarka A, Andrys R, Benkova M, Soukup O, Katalinić M, Kuca K, Kovarik Z, Musilek K.
    J Med Chem; 2018 Dec 13; 61(23):10753-10766. PubMed ID: 30383374
    [Abstract] [Full Text] [Related]

  • 3. Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.
    Zorbaz T, Malinak D, Hofmanova T, Maraković N, Žunec S, Hrvat NM, Andrys R, Psotka M, Zandona A, Svobodova J, Prchal L, Fingler S, Katalinić M, Kovarik Z, Musilek K.
    Eur J Med Chem; 2022 Aug 05; 238():114377. PubMed ID: 35526478
    [Abstract] [Full Text] [Related]

  • 4. Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase.
    Horn G, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.
    Arch Toxicol; 2015 Mar 05; 89(3):405-14. PubMed ID: 24912784
    [Abstract] [Full Text] [Related]

  • 5. Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase.
    Kovarik Z, Katalinić M, Sinko G, Binder J, Holas O, Jung YS, Musilova L, Jun D, Kuca K.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):167-71. PubMed ID: 20206154
    [Abstract] [Full Text] [Related]

  • 6. Reactivation of organophosphate-inhibited serum butyrylcholinesterase by novel substituted phenoxyalkyl pyridinium oximes and traditional oximes.
    Nichols RH, Chambers JE.
    Toxicology; 2021 Mar 30; 452():152719. PubMed ID: 33592259
    [Abstract] [Full Text] [Related]

  • 7. In vitro reactivation of acetylcholinesterase using the oxime K027.
    Kuca K, Kassa J.
    Vet Hum Toxicol; 2004 Feb 30; 46(1):15-8. PubMed ID: 14748409
    [Abstract] [Full Text] [Related]

  • 8. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A, Worek F, Szinicz L, Thiermann H.
    Toxicology; 2007 Apr 20; 233(1-3):166-72. PubMed ID: 16904809
    [Abstract] [Full Text] [Related]

  • 9. Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases.
    Maček Hrvat N, Kalisiak J, Šinko G, Radić Z, Sharpless KB, Taylor P, Kovarik Z.
    Toxicol Lett; 2020 Mar 15; 321():83-89. PubMed ID: 31863869
    [Abstract] [Full Text] [Related]

  • 10. A comparison of the ability of a new bispyridinium oxime--1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Kassa J.
    J Enzyme Inhib Med Chem; 2003 Dec 15; 18(6):529-35. PubMed ID: 15008517
    [Abstract] [Full Text] [Related]

  • 11. Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
    Prchalova E, Andrys R, Pejchal J, Kohoutova Z, Knittelova K, Hofmanova T, Skarka A, Dlabkova A, Psotka M, Prchal L, Musilek K, Karasova JZ, Malinak D.
    Arch Toxicol; 2024 Sep 15; 98(9):2937-2952. PubMed ID: 38789714
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose.
    Shih TM, Skovira JW, O'Donnell JC, McDonough JH.
    Toxicol Mech Methods; 2009 Sep 15; 19(6-7):386-400. PubMed ID: 19778239
    [Abstract] [Full Text] [Related]

  • 13. Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase.
    Amitai G, Plotnikov A, Chapman S, Lazar S, Gez R, Loewenthal D, Shurrush KA, Cohen G, Solmesky LJ, Barr H, Russell AJ.
    Commun Biol; 2021 May 14; 4(1):573. PubMed ID: 33990679
    [Abstract] [Full Text] [Related]

  • 14. Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases.
    Kolić D, Šinko G, Jean L, Chioua M, Dias J, Marco-Contelles J, Kovarik Z.
    Biomolecules; 2024 May 15; 14(5):. PubMed ID: 38785995
    [Abstract] [Full Text] [Related]

  • 15. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents.
    Cadieux CL, Wang H, Zhang Y, Koenig JA, Shih TM, McDonough J, Koh J, Cerasoli D.
    Chem Biol Interact; 2016 Nov 25; 259(Pt B):133-141. PubMed ID: 27062893
    [Abstract] [Full Text] [Related]

  • 16. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides.
    Kohoutova Z, Malinak D, Andrys R, Svobodova J, Psotka M, Schmidt M, Prchal L, Musilek K.
    J Enzyme Inhib Med Chem; 2022 Dec 25; 37(1):760-767. PubMed ID: 35193448
    [Abstract] [Full Text] [Related]

  • 17. New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics.
    Mlakić M, Čadež T, Šinko G, Škorić I, Kovarik Z.
    Biomolecules; 2024 Jun 11; 14(6):. PubMed ID: 38927082
    [Abstract] [Full Text] [Related]

  • 18. New quaternary pyridine aldoximes as casual antidotes against nerve agents intoxications.
    Kuca K, Bartosová L, Jun D, Patocka J, Cabal J, Kassa J, Kunesová G.
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Jun 11; 149(1):75-82. PubMed ID: 16170392
    [Abstract] [Full Text] [Related]

  • 19. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):215-9. PubMed ID: 20105433
    [Abstract] [Full Text] [Related]

  • 20. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

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