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Journal Abstract Search

232 related items for PubMed ID: 31005612

  • 1. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D, Deb M, Kar S, Parbin S, Pradhan N, Patra SK.
    Gene; 2019 Jul 15; 705():22-35. PubMed ID: 31005612
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  • 2. DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop.
    Sengupta D, Deb M, Rath SK, Kar S, Parbin S, Pradhan N, Patra SK.
    Exp Cell Res; 2016 Aug 15; 346(2):176-87. PubMed ID: 27475839
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  • 3. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.
    Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL.
    Mol Endocrinol; 2016 Aug 15; 30(8):856-71. PubMed ID: 27219490
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  • 4. Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer.
    Ling Z, Wang X, Tao T, Zhang L, Guan H, You Z, Lu K, Zhang G, Chen S, Wu J, Qian J, Liu H, Xu B, Chen M.
    J Exp Clin Cancer Res; 2017 Nov 15; 36(1):159. PubMed ID: 29141691
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  • 7. Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia.
    Yin M, Chen Z, Ouyang Y, Zhang H, Wan Z, Wang H, Wu W, Yin X.
    J Neuroinflammation; 2017 Jun 29; 14(1):132. PubMed ID: 28662718
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  • 8. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
    Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.
    J Biol Chem; 2014 Jan 10; 289(2):868-84. PubMed ID: 24235145
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  • 9. MLL1 promotes myogenesis by epigenetically regulating Myf5.
    Cai S, Zhu Q, Guo C, Yuan R, Zhang X, Nie Y, Chen L, Fang Y, Chen K, Zhang J, Mo D, Chen Y.
    Cell Prolif; 2020 Feb 10; 53(2):e12744. PubMed ID: 31840352
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  • 13. The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
    Grinat J, Heuberger J, Vidal RO, Goveas N, Kosel F, Berenguer-Llergo A, Kranz A, Wulf-Goldenberg A, Behrens D, Melcher B, Sauer S, Vieth M, Batlle E, Stewart AF, Birchmeier W.
    Nat Commun; 2020 Dec 21; 11(1):6422. PubMed ID: 33349639
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  • 15. miR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1.
    Colamaio M, Puca F, Ragozzino E, Gemei M, Decaussin-Petrucci M, Aiello C, Bastos AU, Federico A, Chiappetta G, Del Vecchio L, Torregrossa L, Battista S, Fusco A.
    J Clin Endocrinol Metab; 2015 Jan 21; 100(1):E59-69. PubMed ID: 25238203
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  • 16. The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.
    Lu C, Paschall AV, Shi H, Savage N, Waller JL, Sabbatini ME, Oberlies NH, Pearce C, Liu K.
    J Natl Cancer Inst; 2017 Jan 21; 109(6):. PubMed ID: 28131992
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  • 17. Decreased mixed lineage leukemia 1 is involved in endometriosis-related infertility.
    Wen X, Xiong Y, Liu H, Geng T, Jin L, Zhang M, Ma L, Zhang Y.
    J Mol Endocrinol; 2021 Jan 21; 66(1):45-57. PubMed ID: 33151904
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  • 18. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
    Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A.
    Mol Cell Biol; 2009 Nov 21; 29(22):6074-85. PubMed ID: 19703992
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  • 19. The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.
    Carson WF, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.
    J Immunol; 2017 Sep 01; 199(5):1865-1874. PubMed ID: 28733487
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  • 20. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.
    Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.
    Cell Rep; 2019 Jan 08; 26(2):415-428.e5. PubMed ID: 30625324
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