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326 related items for PubMed ID: 3100899

  • 1. MPTP, MPP+ and mitochondrial function.
    Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE.
    Life Sci; 1987 Feb 23; 40(8):721-9. PubMed ID: 3100899
    [Abstract] [Full Text] [Related]

  • 2. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
    Vyas I, Heikkila RE, Nicklas WJ.
    J Neurochem; 1986 May 23; 46(5):1501-7. PubMed ID: 3485701
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine.
    Kindt MV, Heikkila RE, Nicklas WJ.
    J Pharmacol Exp Ther; 1987 Sep 23; 242(3):858-63. PubMed ID: 3498818
    [Abstract] [Full Text] [Related]

  • 4. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 5. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.
    Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP.
    Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651
    [Abstract] [Full Text] [Related]

  • 6. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), its metabolite cyperquat (MPP+) and energy transduction in mitochondria from rat striatum and liver.
    Thakar JH, Hassan MN, Grimes JD.
    Prog Neuropsychopharmacol Biol Psychiatry; 1988 Feb 23; 12(2-3):355-62. PubMed ID: 3260387
    [Abstract] [Full Text] [Related]

  • 7. Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metabolite.
    Heikkila RE, Hwang J, Ofori S, Geller HM, Nicklas WJ.
    J Neurochem; 1990 Mar 23; 54(3):743-50. PubMed ID: 2303810
    [Abstract] [Full Text] [Related]

  • 8. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway.
    Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ.
    Nature; 1990 Mar 23; 319(6048):56-7. PubMed ID: 3484542
    [Abstract] [Full Text] [Related]

  • 9. Participation of brain monoamine oxidase B form in the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: relationship between the enzyme inhibition and the neurotoxicity.
    Kinemuchi H, Arai Y, Toyoshima Y.
    Neurosci Lett; 1985 Jul 31; 58(2):195-200. PubMed ID: 3876524
    [Abstract] [Full Text] [Related]

  • 10. Dopamine-releasing action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion technique: dependence on sodium but not calcium ions.
    Sirinathsinghji DJ, Heavens RP, McBride CS.
    Brain Res; 1988 Mar 08; 443(1-2):101-16. PubMed ID: 3258784
    [Abstract] [Full Text] [Related]

  • 11. MPTP and MPTP analogs induced cell death in cultured rat hepatocytes involving the formation of pyridinium metabolites.
    Singh Y, Swanson E, Sokoloski E, Kutty RK, Krishna G.
    Toxicol Appl Pharmacol; 1988 Nov 08; 96(2):347-59. PubMed ID: 3143167
    [Abstract] [Full Text] [Related]

  • 12. 4-Phenylpyridine (4PP) and MPTP: the relationship between striatal MPP+ concentrations and neurotoxicity.
    Irwin I, Langston JW, DeLanney LE.
    Life Sci; 1987 Feb 23; 40(8):731-40. PubMed ID: 3492652
    [Abstract] [Full Text] [Related]

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  • 17. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity.
    Sershen H, Mason MF, Debler EA, Lajtha A.
    Eur J Pharmacol; 1986 Jul 31; 126(3):337-9. PubMed ID: 3489627
    [Abstract] [Full Text] [Related]

  • 18. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat.
    Harik SI, Schmidley JW, Iacofano LA, Blue P, Arora PK, Sayre LM.
    J Pharmacol Exp Ther; 1987 May 31; 241(2):669-76. PubMed ID: 2437293
    [Abstract] [Full Text] [Related]

  • 19. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver.
    Thakar JH, Hassan MN.
    Life Sci; 1988 May 31; 43(2):143-9. PubMed ID: 3260653
    [Abstract] [Full Text] [Related]

  • 20. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ.
    Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166
    [Abstract] [Full Text] [Related]

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