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7. Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits. Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ. J Neurosci; 2020 Apr 01; 40(14):2960-2974. PubMed ID: 32094203 [Abstract] [Full Text] [Related]
8. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, Martens H, Weber MS, Boretius S, Nave KA, Ehrenreich H. FASEB J; 2019 Jul 01; 33(7):8634-8647. PubMed ID: 31090455 [Abstract] [Full Text] [Related]
9. CSF1R inhibitor PLX3397 depletes microglia in Mongolian gerbil Meriones unguiculatus, but not in syrian hamster Mesocricetus auratus. Sato RY, Zhang Y, Kotake KT, Onishi H, Ito S, Norimoto H, Zhou Z. J Pharmacol Sci; 2024 Jun 01; 155(2):29-34. PubMed ID: 38677783 [Abstract] [Full Text] [Related]
10. CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis. Funk KE, Klein RS. J Neuroinflammation; 2019 Jan 31; 16(1):22. PubMed ID: 30704498 [Abstract] [Full Text] [Related]
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12. CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages. Lei F, Cui N, Zhou C, Chodosh J, Vavvas DG, Paschalis EI. Proc Natl Acad Sci U S A; 2020 Sep 22; 117(38):23336-23338. PubMed ID: 32900927 [Abstract] [Full Text] [Related]
13. Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells. Okojie AK, Uweru JO, Coburn MA, Li S, Cao-Dao VD, Eyo UB. J Neuroinflammation; 2023 Oct 21; 20(1):242. PubMed ID: 37865779 [Abstract] [Full Text] [Related]
14. Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine. da Silva MCM, Gomes GF, de Barros Fernandes H, da Silva AM, Teixeira AL, Moreira FA, de Miranda AS, de Oliveira ACP. Sci Rep; 2021 Aug 06; 11(1):15989. PubMed ID: 34362959 [Abstract] [Full Text] [Related]
15. The CSF1R-Microglia Axis Has Protective Host-Specific Roles During Neurotropic Picornavirus Infection. Sanchez JMS, DePaula-Silva AB, Doty DJ, Hanak TJ, Truong A, Libbey JE, Fujinami RS. Front Immunol; 2021 Aug 06; 12():621090. PubMed ID: 34566948 [Abstract] [Full Text] [Related]
16. Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. Neuron; 2024 Sep 04; 112(17):2910-2921.e7. PubMed ID: 39142282 [Abstract] [Full Text] [Related]
17. Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice. Wang Y, Wernersbach I, Strehle J, Li S, Appel D, Klein M, Ritter K, Hummel R, Tegeder I, Schäfer MKE. Brain Behav Immun; 2022 Nov 04; 106():49-66. PubMed ID: 35933030 [Abstract] [Full Text] [Related]
18. A limited capacity for microglial repopulation in the adult brain. Najafi AR, Crapser J, Jiang S, Ng W, Mortazavi A, West BL, Green KN. Glia; 2018 Nov 04; 66(11):2385-2396. PubMed ID: 30370589 [Abstract] [Full Text] [Related]
19. Microglial repopulation induced by PLX3397 protects against ischemic brain injury by suppressing neuroinflammation in aged mice. Li X, Shan J, Liu X, Huang Z, Xu G, Ren L. Int Immunopharmacol; 2024 Sep 10; 138():112473. PubMed ID: 38943977 [Abstract] [Full Text] [Related]
20. Partial reduction of microglia does not affect tau pathology in aged mice. Bennett RE, Bryant A, Hu M, Robbins AB, Hopp SC, Hyman BT. J Neuroinflammation; 2018 Nov 09; 15(1):311. PubMed ID: 30413160 [Abstract] [Full Text] [Related] Page: [Next] [New Search]