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PUBMED FOR HANDHELDS

Journal Abstract Search


395 related items for PubMed ID: 31029597

  • 1.
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  • 2. Depletion of embryonic microglia using the CSF1R inhibitor PLX5622 has adverse sex-specific effects on mice, including accelerated weight gain, hyperactivity and anxiolytic-like behaviour.
    Rosin JM, Vora SR, Kurrasch DM.
    Brain Behav Immun; 2018 Oct; 73():682-697. PubMed ID: 30056204
    [Abstract] [Full Text] [Related]

  • 3. Effect of the CSF1R inhibitor PLX3397 on remyelination of corpus callosum in a cuprizone-induced demyelination mouse model.
    Tahmasebi F, Pasbakhsh P, Mortezaee K, Madadi S, Barati S, Kashani IR.
    J Cell Biochem; 2019 Jun; 120(6):10576-10586. PubMed ID: 30628737
    [Abstract] [Full Text] [Related]

  • 4. Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice.
    Dagher NN, Najafi AR, Kayala KM, Elmore MR, White TE, Medeiros R, West BL, Green KN.
    J Neuroinflammation; 2015 Aug 01; 12():139. PubMed ID: 26232154
    [Abstract] [Full Text] [Related]

  • 5. Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
    Sosna J, Philipp S, Albay R, Reyes-Ruiz JM, Baglietto-Vargas D, LaFerla FM, Glabe CG.
    Mol Neurodegener; 2018 Mar 01; 13(1):11. PubMed ID: 29490706
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  • 7. Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits.
    Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ.
    J Neurosci; 2020 Apr 01; 40(14):2960-2974. PubMed ID: 32094203
    [Abstract] [Full Text] [Related]

  • 8. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.
    Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, Martens H, Weber MS, Boretius S, Nave KA, Ehrenreich H.
    FASEB J; 2019 Jul 01; 33(7):8634-8647. PubMed ID: 31090455
    [Abstract] [Full Text] [Related]

  • 9. CSF1R inhibitor PLX3397 depletes microglia in Mongolian gerbil Meriones unguiculatus, but not in syrian hamster Mesocricetus auratus.
    Sato RY, Zhang Y, Kotake KT, Onishi H, Ito S, Norimoto H, Zhou Z.
    J Pharmacol Sci; 2024 Jun 01; 155(2):29-34. PubMed ID: 38677783
    [Abstract] [Full Text] [Related]

  • 10. CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
    Funk KE, Klein RS.
    J Neuroinflammation; 2019 Jan 31; 16(1):22. PubMed ID: 30704498
    [Abstract] [Full Text] [Related]

  • 11. Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.
    Stoll AC, Kemp CJ, Patterson JR, Kubik M, Kuhn N, Benskey M, Duffy MF, Luk KC, Sortwell CE.
    J Neuroinflammation; 2024 Apr 25; 21(1):108. PubMed ID: 38664840
    [Abstract] [Full Text] [Related]

  • 12. CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages.
    Lei F, Cui N, Zhou C, Chodosh J, Vavvas DG, Paschalis EI.
    Proc Natl Acad Sci U S A; 2020 Sep 22; 117(38):23336-23338. PubMed ID: 32900927
    [Abstract] [Full Text] [Related]

  • 13. Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells.
    Okojie AK, Uweru JO, Coburn MA, Li S, Cao-Dao VD, Eyo UB.
    J Neuroinflammation; 2023 Oct 21; 20(1):242. PubMed ID: 37865779
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine.
    da Silva MCM, Gomes GF, de Barros Fernandes H, da Silva AM, Teixeira AL, Moreira FA, de Miranda AS, de Oliveira ACP.
    Sci Rep; 2021 Aug 06; 11(1):15989. PubMed ID: 34362959
    [Abstract] [Full Text] [Related]

  • 15. The CSF1R-Microglia Axis Has Protective Host-Specific Roles During Neurotropic Picornavirus Infection.
    Sanchez JMS, DePaula-Silva AB, Doty DJ, Hanak TJ, Truong A, Libbey JE, Fujinami RS.
    Front Immunol; 2021 Aug 06; 12():621090. PubMed ID: 34566948
    [Abstract] [Full Text] [Related]

  • 16. Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism.
    Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R.
    Neuron; 2024 Sep 04; 112(17):2910-2921.e7. PubMed ID: 39142282
    [Abstract] [Full Text] [Related]

  • 17. Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice.
    Wang Y, Wernersbach I, Strehle J, Li S, Appel D, Klein M, Ritter K, Hummel R, Tegeder I, Schäfer MKE.
    Brain Behav Immun; 2022 Nov 04; 106():49-66. PubMed ID: 35933030
    [Abstract] [Full Text] [Related]

  • 18. A limited capacity for microglial repopulation in the adult brain.
    Najafi AR, Crapser J, Jiang S, Ng W, Mortazavi A, West BL, Green KN.
    Glia; 2018 Nov 04; 66(11):2385-2396. PubMed ID: 30370589
    [Abstract] [Full Text] [Related]

  • 19. Microglial repopulation induced by PLX3397 protects against ischemic brain injury by suppressing neuroinflammation in aged mice.
    Li X, Shan J, Liu X, Huang Z, Xu G, Ren L.
    Int Immunopharmacol; 2024 Sep 10; 138():112473. PubMed ID: 38943977
    [Abstract] [Full Text] [Related]

  • 20. Partial reduction of microglia does not affect tau pathology in aged mice.
    Bennett RE, Bryant A, Hu M, Robbins AB, Hopp SC, Hyman BT.
    J Neuroinflammation; 2018 Nov 09; 15(1):311. PubMed ID: 30413160
    [Abstract] [Full Text] [Related]


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