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Journal Abstract Search

198 related items for PubMed ID: 31048139

  • 1. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
    Cai G, Yu W, Song D, Zhang W, Guo J, Zhu J, Ren Y, Kong L.
    Eur J Med Chem; 2019 Jul 15; 174():236-251. PubMed ID: 31048139
    [Abstract] [Full Text] [Related]

  • 2. Antagonizing STAT3 activation with benzo[b]thiophene 1, 1-dioxide based small molecules.
    Zhang W, Ma T, Li S, Yang Y, Guo J, Yu W, Kong L.
    Eur J Med Chem; 2017 Jan 05; 125():538-550. PubMed ID: 27718470
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of benzo[b]thiophene 1,1-dioxide derivatives as potent STAT3 inhibitors.
    Li WZ, Xi HZ, Wang YJ, Ma HB, Cheng ZQ, Yang Y, Wu ML, Liu TM, Yang W, Wang Q, Liao MY, Xia Y, Zhang YW.
    Chem Biol Drug Des; 2021 Nov 05; 98(5):835-849. PubMed ID: 34416096
    [Abstract] [Full Text] [Related]

  • 4. Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway.
    Liu Y, Wang L, Wu Y, Lv C, Li X, Cao X, Yang M, Feng D, Luo Z.
    Toxicology; 2013 Feb 08; 304():120-31. PubMed ID: 23313376
    [Abstract] [Full Text] [Related]

  • 5. Discovery of monocarbonyl curcumin-BTP hybrids as STAT3 inhibitors for drug-sensitive and drug-resistant breast cancer therapy.
    Zhang W, Guo J, Li S, Ma T, Xu D, Han C, Liu F, Yu W, Kong L.
    Sci Rep; 2017 Apr 11; 7():46352. PubMed ID: 28397855
    [Abstract] [Full Text] [Related]

  • 6. LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer.
    Pan L, Chen X, Fu S, Yu W, Li C, Wang T, Lo HW, Lin J.
    Breast Cancer Res Treat; 2020 May 11; 181(1):31-41. PubMed ID: 32240456
    [Abstract] [Full Text] [Related]

  • 7. Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.
    Qiu HY, Zhu X, Luo YL, Lin HY, Tang CY, Qi JL, Pang YJ, Yang RW, Lu GH, Wang XM, Yang YH.
    Sci Rep; 2017 Jun 06; 7(1):2863. PubMed ID: 28588262
    [Abstract] [Full Text] [Related]

  • 8. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells.
    Seo HS, Ku JM, Choi HS, Choi YK, Woo JK, Kim M, Kim I, Na CH, Hur H, Jang BH, Shin YC, Ko SG.
    Oncol Rep; 2016 Jul 06; 36(1):31-42. PubMed ID: 27175602
    [Abstract] [Full Text] [Related]

  • 9. JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
    Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.
    Phytomedicine; 2019 Jan 06; 52():60-69. PubMed ID: 30599913
    [Abstract] [Full Text] [Related]

  • 10. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein.
    Li S, Zhang W, Yang Y, Ma T, Guo J, Wang S, Yu W, Kong L.
    Eur J Med Chem; 2016 Nov 29; 124():1006-1018. PubMed ID: 27783972
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of mitochondria-targeted coumarin-3-carboxamide fluorescent derivatives: Inhibiting mitochondrial TrxR2 and cell proliferation on breast cancer cells.
    Li Y, Tang Q, Xie Y, He D, Yang K, Zheng L.
    Bioorg Med Chem Lett; 2021 Feb 01; 33():127750. PubMed ID: 33340662
    [Abstract] [Full Text] [Related]

  • 12. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW, Kundu J, Chae IG, Kim DH, Yu MH, Kundu JK, Chun KS.
    Int J Oncol; 2014 Apr 01; 44(4):1309-15. PubMed ID: 24481553
    [Abstract] [Full Text] [Related]

  • 13. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug 01; 70(2):259-70. PubMed ID: 22752214
    [Abstract] [Full Text] [Related]

  • 14. Tannic acid inhibits the Jak2/STAT3 pathway and induces G1/S arrest and mitochondrial apoptosis in YD-38 gingival cancer cells.
    Darvin P, Baeg SJ, Joung YH, Sp N, Kang DY, Byun HJ, Park JU, Yang YM.
    Int J Oncol; 2015 Sep 01; 47(3):1111-20. PubMed ID: 26202061
    [Abstract] [Full Text] [Related]

  • 15. Mito-methyl coumarin, a novel mitochondria-targeted drug with great antitumor potential was synthesized.
    Wang H, Xu W.
    Biochem Biophys Res Commun; 2017 Jul 15; 489(1):1-7. PubMed ID: 28546001
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition.
    Li N, Ou J, Bao N, Chen C, Shi Z, Chen L, Sun J.
    Bioorg Chem; 2020 Nov 15; 104():104208. PubMed ID: 32919131
    [Abstract] [Full Text] [Related]

  • 17. Chemical probes that competitively and selectively inhibit Stat3 activation.
    Xu X, Kasembeli MM, Jiang X, Tweardy BJ, Tweardy DJ.
    PLoS One; 2009 Nov 15; 4(3):e4783. PubMed ID: 19274102
    [Abstract] [Full Text] [Related]

  • 18. Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice.
    Mackenzie GG, Huang L, Alston N, Ouyang N, Vrankova K, Mattheolabakis G, Constantinides PP, Rigas B.
    PLoS One; 2013 Nov 15; 8(5):e61532. PubMed ID: 23650499
    [Abstract] [Full Text] [Related]

  • 19. Discovery of an Orally Selective Inhibitor of Signal Transducer and Activator of Transcription 3 Using Advanced Multiple Ligand Simultaneous Docking.
    Yu W, Li C, Zhang W, Xia Y, Li S, Lin JY, Yu K, Liu M, Yang L, Luo J, Chen Y, Sun H, Kong L.
    J Med Chem; 2017 Apr 13; 60(7):2718-2731. PubMed ID: 28245116
    [Abstract] [Full Text] [Related]

  • 20. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.
    Gao D, Jin N, Fu Y, Zhu Y, Wang Y, Wang T, Chen Y, Zhang M, Xiao Q, Huang M, Li Y.
    Eur J Med Chem; 2021 Apr 15; 216():113333. PubMed ID: 33689932
    [Abstract] [Full Text] [Related]

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