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Journal Abstract Search

440 related items for PubMed ID: 31065671

  • 1. Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin.
    Wang Q, Chen X, Jiang Y, Liu S, Liu H, Sun X, Zhang H, Liu Z, Tao Y, Li C, Hu Y, Liu D, Ye D, Liu Y, Wang M, Zhang X.
    J Mol Cell Biol; 2020 Feb 20; 12(2):125-137. PubMed ID: 31065671
    [Abstract] [Full Text] [Related]

  • 2. Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia.
    Li Y, Zhang M, Sheng M, Zhang P, Chen Z, Xing W, Bai J, Cheng T, Yang FC, Zhou Y.
    J Cancer Res Clin Oncol; 2018 Jun 20; 144(6):1065-1077. PubMed ID: 29594337
    [Abstract] [Full Text] [Related]

  • 3. GSKJ4, an H3K27me3 demethylase inhibitor, effectively suppresses the breast cancer stem cells.
    Yan N, Xu L, Wu X, Zhang L, Fei X, Cao Y, Zhang F.
    Exp Cell Res; 2017 Oct 15; 359(2):405-414. PubMed ID: 28823831
    [Abstract] [Full Text] [Related]

  • 4. Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer.
    Zhang J, Ying Y, Li M, Wang M, Huang X, Jia M, Zeng J, Ma C, Zhang Y, Li C, Wang X, Shu XS.
    Theranostics; 2020 Oct 15; 10(22):10016-10030. PubMed ID: 32929331
    [Abstract] [Full Text] [Related]

  • 5. EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells.
    Pediconi N, Salerno D, Lupacchini L, Angrisani A, Peruzzi G, De Smaele E, Levrero M, Belloni L.
    Cell Death Dis; 2019 Jul 08; 10(7):518. PubMed ID: 31285428
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs.
    Mathur R, Sehgal L, Havranek O, Köhrer S, Khashab T, Jain N, Burger JA, Neelapu SS, Davis RE, Samaniego F.
    Haematologica; 2017 Feb 08; 102(2):373-380. PubMed ID: 27742770
    [Abstract] [Full Text] [Related]

  • 7. Effects of GSK-J4 on JMJD3 Histone Demethylase in Mouse Prostate Cancer Xenografts.
    Sanchez A, Penault-Llorca F, Bignon YJ, Guy L, Bernard-Gallon D.
    Cancer Genomics Proteomics; 2022 Feb 08; 19(3):339-349. PubMed ID: 35430567
    [Abstract] [Full Text] [Related]

  • 8. Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin.
    He C, Sun J, Liu C, Jiang Y, Hao Y.
    Clin Epigenetics; 2019 Jan 16; 11(1):8. PubMed ID: 30651137
    [Abstract] [Full Text] [Related]

  • 9. Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
    Cribbs AP, Terlecki-Zaniewicz S, Philpott M, Baardman J, Ahern D, Lindow M, Obad S, Oerum H, Sampey B, Mander PK, Penn H, Wordsworth P, Bowness P, de Winther M, Prinjha RK, Feldmann M, Oppermann U.
    Proc Natl Acad Sci U S A; 2020 Mar 17; 117(11):6056-6066. PubMed ID: 32123118
    [Abstract] [Full Text] [Related]

  • 10. SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
    Romero OA, Vilarrubi A, Alburquerque-Bejar JJ, Gomez A, Andrades A, Trastulli D, Pros E, Setien F, Verdura S, Farré L, Martín-Tejera JF, Llabata P, Oaknin A, Saigi M, Piulats JM, Matias-Guiu X, Medina PP, Vidal A, Villanueva A, Sanchez-Cespedes M.
    Nat Commun; 2021 Jul 14; 12(1):4319. PubMed ID: 34262032
    [Abstract] [Full Text] [Related]

  • 11. GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent.
    Dalpatraj N, Naik A, Thakur N.
    Int J Cancer; 2023 Sep 15; 153(6):1130-1138. PubMed ID: 37165737
    [Abstract] [Full Text] [Related]

  • 12. A KLF4/PiHL/EZH2/HMGA2 regulatory axis and its function in promoting oxaliplatin-resistance of colorectal cancer.
    Deng X, Kong F, Li S, Jiang H, Dong L, Xu X, Zhang X, Yuan H, Xu Y, Chu Y, Peng H, Guan M.
    Cell Death Dis; 2021 May 13; 12(5):485. PubMed ID: 33986248
    [Abstract] [Full Text] [Related]

  • 13. Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma.
    Lochmann TL, Powell KM, Ham J, Floros KV, Heisey DAR, Kurupi RIJ, Calbert ML, Ghotra MS, Greninger P, Dozmorov M, Gowda M, Souers AJ, Reynolds CP, Benes CH, Faber AC.
    Sci Transl Med; 2018 May 16; 10(441):. PubMed ID: 29769286
    [Abstract] [Full Text] [Related]

  • 14. β-hydroxybutyrate resensitizes colorectal cancer cells to oxaliplatin by suppressing H3K79 methylation in vitro and in vivo.
    Deng M, Yan P, Gong H, Li G, Wang J.
    Mol Med; 2024 Jun 23; 30(1):95. PubMed ID: 38910244
    [Abstract] [Full Text] [Related]

  • 15. Histone H3 lysine 27 trimethylation acts as an epigenetic barrier in porcine nuclear reprogramming.
    Xie B, Zhang H, Wei R, Li Q, Weng X, Kong Q, Liu Z.
    Reproduction; 2016 Jan 23; 151(1):9-16. PubMed ID: 26515777
    [Abstract] [Full Text] [Related]

  • 16. The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays.
    Lobo-Silva J, Cabral FJ, Amaral MS, Miyasato PA, de Freitas RP, Pereira ASA, Khouri MI, Barbosa MMF, Ramos PIP, Leite LCC, Asojo OA, Nakano E, Verjovski-Almeida S, Farias LP.
    Parasit Vectors; 2020 Mar 17; 13(1):140. PubMed ID: 32178714
    [Abstract] [Full Text] [Related]

  • 17. Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo.
    Wen S, Wang J, Liu P, Li Y, Lu W, Hu Y, Liu J, He Z, Huang P.
    Cancer Lett; 2018 Jan 28; 413():35-45. PubMed ID: 29069576
    [Abstract] [Full Text] [Related]

  • 18. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
    Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, Pataer A, Swisher SG, Kalhor N, Bhanu NV, Garcia BA, Heymach JV, Coombes K, Xie Y, Girard L, Gazdar AF, Kittler R, Wistuba II, Minna JD, Martinez ED.
    Cell Rep; 2017 May 23; 19(8):1669-1684. PubMed ID: 28538184
    [Abstract] [Full Text] [Related]

  • 19. Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.
    Peng K, Kou L, Yu L, Bai C, Li M, Mo P, Li W, Yu C.
    Gastroenterology; 2019 Mar 23; 156(4):1112-1126. PubMed ID: 30472235
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of H3K27me3 Demethylases Promotes Plasmablast Formation.
    Kania AK, Guo M, Scharer CD, Boss JM.
    Immunohorizons; 2021 Dec 08; 5(12):918-930. PubMed ID: 34880105
    [Abstract] [Full Text] [Related]

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