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466 related items for PubMed ID: 31106349

  • 1. A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes.
    El-Battrawy I, Albers S, Cyganek L, Zhao Z, Lan H, Li X, Xu Q, Kleinsorge M, Huang M, Liao Z, Zhong R, Rudic B, Müller J, Dinkel H, Lang S, Diecke S, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou X, Akin I.
    Europace; 2019 Sep 01; 21(9):1410-1421. PubMed ID: 31106349
    [Abstract] [Full Text] [Related]

  • 2. hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities.
    Veerman CC, Mengarelli I, Guan K, Stauske M, Barc J, Tan HL, Wilde AA, Verkerk AO, Bezzina CR.
    Sci Rep; 2016 Aug 03; 6():30967. PubMed ID: 27485484
    [Abstract] [Full Text] [Related]

  • 3. Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes.
    Casini S, Marchal GA, Kawasaki M, Nariswari FA, Portero V, van den Berg NWE, Guan K, Driessen AHG, Veldkamp MW, Mengarelli I, de Groot JR, Verkerk AO, Remme CA.
    Cardiovasc Drugs Ther; 2019 Dec 03; 33(6):649-660. PubMed ID: 31916131
    [Abstract] [Full Text] [Related]

  • 4. Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.
    Miller DC, Harmer SC, Poliandri A, Nobles M, Edwards EC, Ware JS, Sharp TV, McKay TR, Dunkel L, Lambiase PD, Tinker A.
    Stem Cell Res; 2017 Dec 03; 25():233-244. PubMed ID: 29172153
    [Abstract] [Full Text] [Related]

  • 5. Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome.
    Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, Churko J, Hu S, Sharma A, Lam CK, Scheinman MM, Bers DM, Wu JC.
    J Am Coll Cardiol; 2016 Nov 08; 68(19):2086-2096. PubMed ID: 27810048
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  • 7. Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes.
    Li Y, Dinkel H, Pakalniskyte D, Busley AV, Cyganek L, Zhong R, Zhang F, Xu Q, Maywald L, Aweimer A, Huang M, Liao Z, Meng Z, Yan C, Prädel T, Rose L, Moscu-Gregor A, Hohn A, Yang Z, Qiao L, Mügge A, Zhou X, Akin I, El-Battrawy I.
    Clin Transl Med; 2023 Mar 08; 13(3):e1130. PubMed ID: 36881552
    [Abstract] [Full Text] [Related]

  • 8. A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells.
    Zhong R, Schimanski T, Zhang F, Lan H, Hohn A, Xu Q, Huang M, Liao Z, Qiao L, Yang Z, Li Y, Zhao Z, Li X, Rose L, Albers S, Maywald L, Müller J, Dinkel H, Saguner A, Janssen JWG, Swamy N, Xi Y, Lang S, Kleinsorge M, Duru F, Zhou X, Diecke S, Cyganek L, Akin I, El-Battrawy I.
    Int J Mol Sci; 2022 Jul 27; 23(15):. PubMed ID: 35955449
    [Abstract] [Full Text] [Related]

  • 9. Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.
    Behr ER, Savio-Galimberti E, Barc J, Holst AG, Petropoulou E, Prins BP, Jabbari J, Torchio M, Berthet M, Mizusawa Y, Yang T, Nannenberg EA, Dagradi F, Weeke P, Bastiaenan R, Ackerman MJ, Haunso S, Leenhardt A, Kääb S, Probst V, Redon R, Sharma S, Wilde A, Tfelt-Hansen J, Schwartz P, Roden DM, Bezzina CR, Olesen M, Darbar D, Guicheney P, Crotti L, UK10K Consortium, Jamshidi Y.
    Cardiovasc Res; 2015 Jun 01; 106(3):520-9. PubMed ID: 25691538
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  • 11. Novel SCN10A variants associated with Brugada syndrome.
    Fukuyama M, Ohno S, Makiyama T, Horie M.
    Europace; 2016 Jun 01; 18(6):905-11. PubMed ID: 25842276
    [Abstract] [Full Text] [Related]

  • 12. Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels.
    de la Roche J, Angsutararux P, Kempf H, Janan M, Bolesani E, Thiemann S, Wojciechowski D, Coffee M, Franke A, Schwanke K, Leffler A, Luanpitpong S, Issaragrisil S, Fischer M, Zweigerdt R.
    Sci Rep; 2019 Aug 01; 9(1):11173. PubMed ID: 31371804
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  • 14. Identification of an INa-dependent and Ito-mediated proarrhythmic mechanism in cardiomyocytes derived from pluripotent stem cells of a Brugada syndrome patient.
    Ma D, Liu Z, Loh LJ, Zhao Y, Li G, Liew R, Islam O, Wu J, Chung YY, Teo WS, Ching CK, Tan BY, Chong D, Ho KL, Lim P, Yong RYY, Panama BK, Kaplan AD, Bett GCL, Ware J, Bezzina CR, Verkerk AO, Cook SA, Rasmusson RL, Wei H.
    Sci Rep; 2018 Jul 26; 8(1):11246. PubMed ID: 30050137
    [Abstract] [Full Text] [Related]

  • 15. Contribution of the neuronal sodium channel NaV1.8 to sodium- and calcium-dependent cellular proarrhythmia.
    Bengel P, Ahmad S, Tirilomis P, Trum M, Dybkova N, Wagner S, Maier LS, Hasenfuß G, Sossalla S.
    J Mol Cell Cardiol; 2020 Jul 26; 144():35-46. PubMed ID: 32418916
    [Abstract] [Full Text] [Related]

  • 16. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.
    Hu D, Barajas-Martínez H, Pfeiffer R, Dezi F, Pfeiffer J, Buch T, Betzenhauser MJ, Belardinelli L, Kahlig KM, Rajamani S, DeAntonio HJ, Myerburg RJ, Ito H, Deshmukh P, Marieb M, Nam GB, Bhatia A, Hasdemir C, Haïssaguerre M, Veltmann C, Schimpf R, Borggrefe M, Viskin S, Antzelevitch C.
    J Am Coll Cardiol; 2014 Jul 08; 64(1):66-79. PubMed ID: 24998131
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  • 17. Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype.
    Cerrone M, Lin X, Zhang M, Agullo-Pascual E, Pfenniger A, Chkourko Gusky H, Novelli V, Kim C, Tirasawadichai T, Judge DP, Rothenberg E, Chen HS, Napolitano C, Priori SG, Delmar M.
    Circulation; 2014 Mar 11; 129(10):1092-103. PubMed ID: 24352520
    [Abstract] [Full Text] [Related]

  • 18. Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
    Nieto-Marín P, Tinaquero D, Utrilla RG, Cebrián J, González-Guerra A, Crespo-García T, Cámara-Checa A, Rubio-Alarcón M, Dago M, Alfayate S, Filgueiras-Rama D, Peinado R, López-Sendón JL, Jalife J, Tamargo J, Bernal JA, Caballero R, Delpón E, ITACA Consortium Investigators.
    Cardiovasc Res; 2022 Mar 16; 118(4):1046-1060. PubMed ID: 33576403
    [Abstract] [Full Text] [Related]

  • 19. Biophysical comparison of sodium currents in native cardiac myocytes and human induced pluripotent stem cell-derived cardiomyocytes.
    Goodrow RJ, Desai S, Treat JA, Panama BK, Desai M, Nesterenko VV, Cordeiro JM.
    J Pharmacol Toxicol Methods; 2018 Mar 16; 90():19-30. PubMed ID: 29128504
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