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Journal Abstract Search

304 related items for PubMed ID: 31109089

  • 1. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
    Tataranni T, Agriesti F, Pacelli C, Ruggieri V, Laurenzana I, Mazzoccoli C, Sala GD, Panebianco C, Pazienza V, Capitanio N, Piccoli C.
    Cells; 2019 May 18; 8(5):. PubMed ID: 31109089
    [Abstract] [Full Text] [Related]

  • 2. Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
    Ruggieri V, Agriesti F, Scrima R, Laurenzana I, Perrone D, Tataranni T, Mazzoccoli C, Lo Muzio L, Capitanio N, Piccoli C.
    Oncotarget; 2015 Jan 20; 6(2):1217-30. PubMed ID: 25544754
    [Abstract] [Full Text] [Related]

  • 3. Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
    Roh JL, Park JY, Kim EH, Jang HJ, Kwon M.
    Cancer Lett; 2016 Feb 01; 371(1):20-9. PubMed ID: 26607904
    [Abstract] [Full Text] [Related]

  • 4. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
    Kinnaird A, Dromparis P, Saleme B, Gurtu V, Watson K, Paulin R, Zervopoulos S, Stenson T, Sutendra G, Pink DB, Carmine-Simmen K, Moore R, Lewis JD, Michelakis ED.
    Eur Urol; 2016 Apr 01; 69(4):734-744. PubMed ID: 26433571
    [Abstract] [Full Text] [Related]

  • 5. Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.
    Stockwin LH, Yu SX, Borgel S, Hancock C, Wolfe TL, Phillips LR, Hollingshead MG, Newton DL.
    Int J Cancer; 2010 Dec 01; 127(11):2510-9. PubMed ID: 20533281
    [Abstract] [Full Text] [Related]

  • 6. High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate.
    Hanberry BS, Berger R, Zastre JA.
    Cancer Chemother Pharmacol; 2014 Mar 01; 73(3):585-94. PubMed ID: 24452394
    [Abstract] [Full Text] [Related]

  • 7. The effect of dichloroacetate in canine prostate adenocarcinomas and transitional cell carcinomas in vitro.
    Harting T, Stubbendorff M, Willenbrock S, Wagner S, Schadzek P, Ngezahayo A, Murua Escobar HM, Nolte I.
    Int J Oncol; 2016 Dec 01; 49(6):2341-2350. PubMed ID: 27748833
    [Abstract] [Full Text] [Related]

  • 8. Targeting of two aspects of metabolism in breast cancer treatment.
    Gang BP, Dilda PJ, Hogg PJ, Blackburn AC.
    Cancer Biol Ther; 2014 Dec 01; 15(11):1533-41. PubMed ID: 25482950
    [Abstract] [Full Text] [Related]

  • 9. Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
    Niewisch MR, Kuçi Z, Wolburg H, Sautter M, Krampen L, Deubzer B, Handgretinger R, Bruchelt G.
    Cell Physiol Biochem; 2012 Dec 01; 29(3-4):373-80. PubMed ID: 22508045
    [Abstract] [Full Text] [Related]

  • 10. Dual-targeting of aberrant glucose metabolism in glioblastoma.
    Shen H, Decollogne S, Dilda PJ, Hau E, Chung SA, Luk PP, Hogg PJ, McDonald KL.
    J Exp Clin Cancer Res; 2015 Feb 05; 34(1):14. PubMed ID: 25652202
    [Abstract] [Full Text] [Related]

  • 11. Synergistic anticancer potential of dichloroacetate and estradiol analogue exerting their effect via ROS-JNK-Bcl-2-mediated signalling pathways.
    Stander XX, Stander BA, Joubert AM.
    Cell Physiol Biochem; 2015 Feb 05; 35(4):1499-526. PubMed ID: 25791820
    [Abstract] [Full Text] [Related]

  • 12. Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells.
    Sun L, Jiang Y, Yan X, Dai X, Huang C, Chen L, Li T, Zhang Y, Xiao H, Yang M, Xiang L, Zhang Y, Chen S, Li S, Chen A, He F, Lian J.
    Exp Cell Res; 2021 Sep 01; 406(1):112755. PubMed ID: 34332981
    [Abstract] [Full Text] [Related]

  • 13. Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.
    Kluza J, Corazao-Rozas P, Touil Y, Jendoubi M, Maire C, Guerreschi P, Jonneaux A, Ballot C, Balayssac S, Valable S, Corroyer-Dulmont A, Bernaudin M, Malet-Martino M, de Lassalle EM, Maboudou P, Formstecher P, Polakowska R, Mortier L, Marchetti P.
    Cancer Res; 2012 Oct 01; 72(19):5035-47. PubMed ID: 22865452
    [Abstract] [Full Text] [Related]

  • 14. Dichloroacetate stimulates changes in the mitochondrial network morphology via partial mitophagy in human SH-SY5Y neuroblastoma cells.
    Pajuelo-Reguera D, Alán L, Olejár T, Ježek P.
    Int J Oncol; 2015 Oct 01; 46(6):2409-18. PubMed ID: 25846762
    [Abstract] [Full Text] [Related]

  • 15. Dichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levels.
    Dai Y, Xiong X, Huang G, Liu J, Sheng S, Wang H, Qin W.
    PLoS One; 2014 Oct 01; 9(4):e92962. PubMed ID: 24728083
    [Abstract] [Full Text] [Related]

  • 16. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
    Neveu MA, De Preter G, Joudiou N, Bol A, Brender JR, Saito K, Kishimoto S, Grégoire V, Jordan BF, Krishna MC, Feron O, Gallez B.
    Oncotarget; 2016 Dec 06; 7(49):81741-81749. PubMed ID: 28082726
    [Abstract] [Full Text] [Related]

  • 17. Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer.
    Liu X, Li J, Huang Q, Jin M, Huang G.
    Mol Med; 2024 Apr 26; 30(1):56. PubMed ID: 38671369
    [Abstract] [Full Text] [Related]

  • 18. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate.
    Schoonjans CA, Joudiou N, Brusa D, Corbet C, Feron O, Gallez B.
    Cancer Lett; 2020 Feb 01; 470():18-28. PubMed ID: 31812695
    [Abstract] [Full Text] [Related]

  • 19. Hypoxia enhances antitumor activity of dichloroacetate.
    Kolesnik DL, Pyaskovskaya ON, Boichuk IV, Solyanik GI.
    Exp Oncol; 2014 Dec 01; 36(4):231-5. PubMed ID: 25537215
    [Abstract] [Full Text] [Related]

  • 20. DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism.
    Du J, Wang X, Li Y, Ren X, Zhou Y, Hu W, Zhou C, Jing Q, Yang C, Wang L, Li H, Fang L, Zhou Y, Tong X, Wang Y.
    Cell Death Dis; 2021 Jul 15; 12(7):705. PubMed ID: 34262021
    [Abstract] [Full Text] [Related]

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