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Journal Abstract Search

365 related items for PubMed ID: 31109275

  • 1. Identification of Essential 2D and 3D Chemical Features for Discovery of the Novel Tubulin Polymerization Inhibitors.
    Azimi F, Ghasemi JB, Saghaei L, Hassanzadeh F, Mahdavi M, Sadeghi-Aliabadi H, Scotti MT, Scotti L.
    Curr Top Med Chem; 2019; 19(13):1092-1120. PubMed ID: 31109275
    [Abstract] [Full Text] [Related]

  • 2. Application of GA-MLR for QSAR Modeling of the Arylthioindole Class of Tubulin Polymerization Inhibitors as Anticancer Agents.
    Ahmadi S, Habibpour E.
    Anticancer Agents Med Chem; 2017; 17(4):552-565. PubMed ID: 27528182
    [Abstract] [Full Text] [Related]

  • 3. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
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  • 4. Tubulin inhibitors: pharmacophore modeling, virtual screening and molecular docking.
    Niu MM, Qin JY, Tian CP, Yan XF, Dong FG, Cheng ZQ, Fida G, Yang M, Chen HY, Gu YQ.
    Acta Pharmacol Sin; 2014 Jul 01; 35(7):967-79. PubMed ID: 24909516
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  • 5. Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors.
    Wang Z, Liu R, Zhang X, Chang X, Gao M, Zhang S, Guan Q, Sun J, Zuo D, Zhang W.
    Bioorg Med Chem; 2022 Mar 15; 58():116671. PubMed ID: 35193066
    [Abstract] [Full Text] [Related]

  • 6. QSAR Modeling of the Arylthioindole Class of Colchicine Polymerization Inhibitors as Anticancer Agents.
    Habibpour E, Ahmadi S.
    Curr Comput Aided Drug Des; 2017 Mar 15; 13(2):143-159. PubMed ID: 28120704
    [Abstract] [Full Text] [Related]

  • 7. Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation.
    Liu W, Jia H, Guan M, Cui M, Lan Z, He Y, Guo Z, Jiang R, Dong G, Wang S.
    Bioorg Chem; 2022 Jan 15; 118():105486. PubMed ID: 34801948
    [Abstract] [Full Text] [Related]

  • 8. Combined Molecular Docking, 3D-QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine-binding Site.
    Li DD, Qin YJ, Zhang X, Yin Y, Zhu HL, Zhao LG.
    Chem Biol Drug Des; 2015 Oct 15; 86(4):731-45. PubMed ID: 25711282
    [Abstract] [Full Text] [Related]

  • 9. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 10. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):640-658. PubMed ID: 33588683
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  • 11. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U, Urbaniak A, Maj E, Moshari M, Delgado M, Wietrzyk J, Bartl F, Chambers TC, Tuszynski JA, Huczyński A.
    Bioorg Chem; 2018 Dec 01; 81():553-566. PubMed ID: 30248507
    [Abstract] [Full Text] [Related]

  • 12. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B, Zhu G, Meng L, Wu G, Chen Q, Ma S.
    Eur J Med Chem; 2022 Jan 15; 228():113930. PubMed ID: 34794817
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 14. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A, Khodarahmi G, Forootanfar H, Hassanzadeh F, Hakimelahi GH.
    Chem Biodivers; 2018 Mar 15; 15(3):e1700518. PubMed ID: 29292595
    [Abstract] [Full Text] [Related]

  • 15. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 16. Tubulin inhibitory activity of a novel colchicine-binding compounds based on a dinaphthospiropyranran scaffold.
    Sundriyal S, Eeda V, Lagisetty P, Awasthi V.
    Bioorg Med Chem; 2021 Jan 01; 29():115874. PubMed ID: 33223461
    [Abstract] [Full Text] [Related]

  • 17. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
    Maklad RM, AbdelHafez EMN, Abdelhamid D, Aly OM.
    Bioorg Chem; 2020 Jun 01; 99():103767. PubMed ID: 32325332
    [Abstract] [Full Text] [Related]

  • 18. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
    Zhang H, Luo QQ, Hu ML, Wang N, Qi HZ, Zhang HR, Ding L.
    Eur J Pharm Sci; 2023 Jan 01; 180():106340. PubMed ID: 36435355
    [Abstract] [Full Text] [Related]

  • 19. Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors.
    Sardaru MC, Craciun AM, Al Matarneh CM, Sandu IA, Amarandi RM, Popovici L, Ciobanu CI, Peptanariu D, Pinteala M, Mangalagiu II, Danac R.
    J Enzyme Inhib Med Chem; 2020 Dec 01; 35(1):1581-1595. PubMed ID: 32752898
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

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