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Journal Abstract Search

365 related items for PubMed ID: 31109275

  • 21. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
    Wang Y, Zhang H, Gigant B, Yu Y, Wu Y, Chen X, Lai Q, Yang Z, Chen Q, Yang J.
    FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
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  • 22. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
    J Med Chem; 2009 Jul 23; 52(14):4221-33. PubMed ID: 19507860
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  • 23. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
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  • 24. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
    Romagnoli R, Oliva P, Salvador MK, Manfredini S, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2021 Mar 15; 214():113229. PubMed ID: 33550186
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  • 25. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
    Guo Q, Zhang H, Deng Y, Zhai S, Jiang Z, Zhu D, Wang L.
    Eur J Med Chem; 2020 Jun 15; 196():112328. PubMed ID: 32320841
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  • 26. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
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  • 27. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
    Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL.
    Eur J Med Chem; 2021 Aug 05; 220():113449. PubMed ID: 33895499
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  • 28. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization.
    Wang SY, Liu X, Meng LW, Li MM, Li YR, Yu GX, Song J, Zhang HY, Chen P, Zhang SY, Hu T.
    Bioorg Med Chem Lett; 2021 Jul 01; 43():128095. PubMed ID: 33965530
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  • 29. Design, synthesis, and biological evaluation of novel 2,3-Di-O-Aryl/Alkyl sulfonate derivatives of l-ascorbic acid: Efficient access to novel anticancer agents via in vitro screening, tubulin polymerization inhibition, molecular docking study and ADME predictions.
    Deshmukh SR, Nalkar AS, Sarkate AP, Tiwari SV, Lokwani DK, Thopate SR.
    Bioorg Chem; 2024 Jun 01; 147():107402. PubMed ID: 38688199
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  • 30. Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity.
    Zhou Y, Di B, Niu MM.
    Molecules; 2019 Sep 01; 24(17):. PubMed ID: 31480625
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  • 31. In Silico Exploration of Novel Tubulin Inhibitors: A Combination of Docking and Molecular Dynamics Simulations, Pharmacophore Modeling, and Virtual Screening.
    Hadizadeh F, Ghodsi R, Mirzaei S, Sahebkar A.
    Comput Math Methods Med; 2022 Sep 01; 2022():4004068. PubMed ID: 35075369
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  • 32. 3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity.
    Mirzaei S, Ghodsi R, Hadizadeh F, Sahebkar A.
    Biomed Res Int; 2021 Sep 01; 2021():6480804. PubMed ID: 34485522
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  • 33. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
    Moussa SA, A Osman EE, Eid NM, Abou-Seri SM, El Moghazy SM.
    Future Med Chem; 2018 Aug 01; 10(16):1907-1924. PubMed ID: 29966433
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  • 34. A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
    Al-Hamashi AA, Koranne R, Dlamini S, Alqahtani A, Karaj E, Rashid MS, Knoff JR, Dunworth M, Pflum MKH, Casero RA, Perera L, Taylor WR, Tillekeratne LMV.
    Bioorg Chem; 2021 Nov 01; 116():105297. PubMed ID: 34509798
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  • 35. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
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  • 36. Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors.
    Fu DJ, Liu SM, Li FH, Yang JJ, Li J.
    J Enzyme Inhib Med Chem; 2020 Dec 06; 35(1):1050-1059. PubMed ID: 32299262
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  • 37. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
    Liang T, Zhou X, Lu L, Dong H, Zhang Y, Xu Y, Qi J, Zhang Y, Wang J.
    Bioorg Chem; 2021 May 06; 110():104793. PubMed ID: 33770673
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  • 38. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
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  • 39. Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies.
    Abdelhameid MK, Taher ES, Hara MA, Ramadan M, Mohamed KO.
    Bioorg Chem; 2024 Jul 01; 148():107449. PubMed ID: 38759356
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  • 40. Virtual and experimental high throughput screening of substituted hydrazones on β-Tubulin polymerization.
    Xavier JS, Jayabalan K, Ragavendran V, Manoharan MT, Nityananda Shetty A.
    Bioorg Chem; 2021 Sep 01; 114():105094. PubMed ID: 34167017
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