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Journal Abstract Search

375 related items for PubMed ID: 31120744

  • 1. Hydroxamic Acid Derivatives of β-Carboline/Hydroxycinnamic Acid Hybrids Inducing Apoptosis and Autophagy through the PI3K/Akt/mTOR Pathways.
    Ling Y, Li Y, Zhu R, Qian J, Liu J, Gao W, Meng C, Miao J, Xiong B, Qiu X, Ling C, Dai H, Zhang Y.
    J Nat Prod; 2019 Jun 28; 82(6):1442-1450. PubMed ID: 31120744
    [Abstract] [Full Text] [Related]

  • 2. Novel β-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway.
    Ling Y, Xu C, Luo L, Cao J, Feng J, Xue Y, Zhu Q, Ju C, Li F, Zhang Y, Zhang Y, Ling X.
    J Med Chem; 2015 Dec 10; 58(23):9214-27. PubMed ID: 26555243
    [Abstract] [Full Text] [Related]

  • 3. Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with antiproliferative and antimetastatic activities in human cancer cells.
    Ling Y, Guo J, Yang Q, Zhu P, Miao J, Gao W, Peng Y, Yang J, Xu K, Xiong B, Liu G, Tao J, Luo L, Zhu Q, Zhang Y.
    Eur J Med Chem; 2018 Jan 20; 144():398-409. PubMed ID: 29288941
    [Abstract] [Full Text] [Related]

  • 4. Histone Deacetylase Inhibitor Trichostatin A Suppresses Cell Proliferation and Induces Apoptosis by Regulating the PI3K/AKT Signalling Pathway in Gastric Cancer Cells.
    An X, Wei Z, Ran B, Tian H, Gu H, Liu Y, Cui H, Zhu S.
    Anticancer Agents Med Chem; 2020 Jan 20; 20(17):2114-2124. PubMed ID: 32593284
    [Abstract] [Full Text] [Related]

  • 5. β-Carboline and N-hydroxycinnamamide hybrids as anticancer agents for drug-resistant hepatocellular carcinoma.
    Ling Y, Gao WJ, Ling C, Liu J, Meng C, Qian J, Liu S, Gan H, Wu H, Tao J, Dai H, Zhang Y.
    Eur J Med Chem; 2019 Apr 15; 168():515-526. PubMed ID: 30851694
    [Abstract] [Full Text] [Related]

  • 6. Design and Synthesis of C3-Substituted β-Carboline-Based Histone Deacetylase Inhibitors with Potent Antitumor Activities.
    Ling Y, Feng J, Luo L, Guo J, Peng Y, Wang T, Ge X, Xu Q, Wang X, Dai H, Zhang Y.
    ChemMedChem; 2017 May 09; 12(9):646-651. PubMed ID: 28425177
    [Abstract] [Full Text] [Related]

  • 7. [Effect of Shikonin on Autophagy and Apoptosis of Human Promyelocytic Leukemia Cells].
    Chen Y, Xie XM, Zhang XL, Zhang XL.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Apr 09; 32(2):416-421. PubMed ID: 38660845
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, Biological Evaluation, and Computer-Aided Drug Designing of New Derivatives of Hyperactive Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitors.
    Zhang S, Huang W, Li X, Yang Z, Feng B.
    Chem Biol Drug Des; 2015 Oct 09; 86(4):795-804. PubMed ID: 25763653
    [Abstract] [Full Text] [Related]

  • 9. CLE-10 from Carpesium abrotanoides L. Suppresses the Growth of Human Breast Cancer Cells (MDA-MB-231) In Vitro by Inducing Apoptosis and Pro-Death Autophagy Via the PI3K/Akt/mTOR Signaling Pathway.
    Tian L, Cheng F, Wang L, Qin W, Zou K, Chen J.
    Molecules; 2019 Mar 20; 24(6):. PubMed ID: 30897708
    [Abstract] [Full Text] [Related]

  • 10. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.
    Carcinogenesis; 2013 Jun 20; 34(6):1331-42. PubMed ID: 23393227
    [Abstract] [Full Text] [Related]

  • 11. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J, Jiang YY, Chen H, Wu YC, Zhang L.
    Cell Prolif; 2020 Feb 20; 53(2):e12739. PubMed ID: 31820522
    [Abstract] [Full Text] [Related]

  • 12. Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway.
    Yue Z, Guan X, Chao R, Huang C, Li D, Yang P, Liu S, Hasegawa T, Guo J, Li M.
    Molecules; 2019 Jul 23; 24(14):. PubMed ID: 31340526
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors.
    Jiang BE, Hu J, Liu H, Liu Z, Wen Y, Liu M, Zhang HK, Pang X, Yu LF.
    Eur J Med Chem; 2022 Jan 05; 227():113893. PubMed ID: 34656899
    [Abstract] [Full Text] [Related]

  • 14. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Jan 05; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 15. Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells.
    Hu JL, Hu XL, Guo AY, Wang CJ, Wen YY, Cang SD.
    Oncotarget; 2017 Jul 25; 8(30):49380-49394. PubMed ID: 28537902
    [Abstract] [Full Text] [Related]

  • 16. Ganoderic acid A holds promising cytotoxicity on human glioblastoma mediated by incurring apoptosis and autophagy and inactivating PI3K/AKT signaling pathway.
    Cheng Y, Xie P.
    J Biochem Mol Toxicol; 2019 Nov 25; 33(11):e22392. PubMed ID: 31503386
    [Abstract] [Full Text] [Related]

  • 17. Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling.
    Chang CH, Lee CY, Lu CC, Tsai FJ, Hsu YM, Tsao JW, Juan YN, Chiu HY, Yang JS, Wang CC.
    Int J Oncol; 2017 Mar 25; 50(3):873-882. PubMed ID: 28197628
    [Abstract] [Full Text] [Related]

  • 18. Procyanidins, from Castanea mollissima Bl. shell, induces autophagy following apoptosis associated with PI3K/AKT/mTOR inhibition in HepG2 cells.
    Zhang H, Luo X, Ke J, Duan Y, He Y, Zhang D, Cai M, Sun G, Sun X.
    Biomed Pharmacother; 2016 Jul 25; 81():15-24. PubMed ID: 27261572
    [Abstract] [Full Text] [Related]

  • 19. Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells.
    Singh BN, Kumar D, Shankar S, Srivastava RK.
    Biochem Pharmacol; 2012 Nov 01; 84(9):1154-63. PubMed ID: 22902833
    [Abstract] [Full Text] [Related]

  • 20. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 01; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

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