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302 related items for PubMed ID: 31125447

  • 1. Hypervascularization in mTOR-dependent focal and global cortical malformations displays differential rapamycin sensitivity.
    Zhang L, Huang T, Teaw S, Bordey A.
    Epilepsia; 2019 Jun; 60(6):1255-1265. PubMed ID: 31125447
    [Abstract] [Full Text] [Related]

  • 2. mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia.
    Nguyen LH, Mahadeo T, Bordey A.
    J Neurosci; 2019 Apr 03; 39(14):2762-2773. PubMed ID: 30700531
    [Abstract] [Full Text] [Related]

  • 3. mTOR signaling in epilepsy: insights from malformations of cortical development.
    Crino PB.
    Cold Spring Harb Perspect Med; 2015 Apr 01; 5(4):. PubMed ID: 25833943
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  • 4. Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement.
    Hsieh LS, Wen JH, Claycomb K, Huang Y, Harrsch FA, Naegele JR, Hyder F, Buchanan GF, Bordey A.
    Nat Commun; 2016 Jun 01; 7():11753. PubMed ID: 27249187
    [Abstract] [Full Text] [Related]

  • 5. Rapamycin Cannot Reduce Seizure Susceptibility in Infantile Rats with Malformations of Cortical Development Lacking mTORC1 Activation.
    Lee M, Kim EJ, Kim MJ, Yum MS.
    Mol Neurobiol; 2022 Dec 01; 59(12):7439-7449. PubMed ID: 36194361
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  • 6. mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
    Nguyen LH, Brewster AL, Clark ME, Regnier-Golanov A, Sunnen CN, Patil VV, D'Arcangelo G, Anderson AE.
    Epilepsia; 2015 Apr 01; 56(4):636-46. PubMed ID: 25752454
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  • 7. Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations.
    Wong M.
    Exp Neurol; 2013 Jun 01; 244():22-6. PubMed ID: 22015915
    [Abstract] [Full Text] [Related]

  • 8. Intermittent dosing of rapamycin maintains antiepileptogenic effects in a mouse model of tuberous sclerosis complex.
    Rensing N, Han L, Wong M.
    Epilepsia; 2015 Jul 01; 56(7):1088-97. PubMed ID: 26122303
    [Abstract] [Full Text] [Related]

  • 9. Targeting the Mammalian Target of Rapamycin for Epileptic Encephalopathies and Malformations of Cortical Development.
    Jeong A, Wong M.
    J Child Neurol; 2018 Jan 01; 33(1):55-63. PubMed ID: 29246093
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  • 14. NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold.
    Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB.
    Brain; 2022 Nov 21; 145(11):3872-3885. PubMed ID: 35136953
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  • 15. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility.
    Yuskaitis CJ, Jones BM, Wolfson RL, Super CE, Dhamne SC, Rotenberg A, Sabatini DM, Sahin M, Poduri A.
    Neurobiol Dis; 2018 Mar 21; 111():91-101. PubMed ID: 29274432
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  • 16. mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis.
    Yasin SA, Ali AM, Tata M, Picker SR, Anderson GW, Latimer-Bowman E, Nicholson SL, Harkness W, Cross JH, Paine SM, Jacques TS.
    Acta Neuropathol; 2013 Aug 21; 126(2):207-18. PubMed ID: 23728790
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  • 18. Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.
    Anderl S, Freeland M, Kwiatkowski DJ, Goto J.
    Hum Mol Genet; 2011 Dec 01; 20(23):4597-604. PubMed ID: 21890496
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  • 19. Brain somatic mutations in MTOR leading to focal cortical dysplasia.
    Lim JS, Lee JH.
    BMB Rep; 2016 Feb 01; 49(2):71-2. PubMed ID: 26779999
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