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990 related items for PubMed ID: 31132129

  • 1. The TGFβ1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice.
    McMillin M, Grant S, Frampton G, Petrescu AD, Williams E, Jefferson B, DeMorrow S.
    Toxicol Sci; 2019 May 01; 170(2):549-561. PubMed ID: 31132129
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of thrombospondin-1 reduces glutathione activity and worsens acute liver injury during acetaminophen hepatotoxicity in mice.
    Frampton G, Reddy P, Jefferson B, Ali M, Khan D, McMillin M.
    Toxicol Appl Pharmacol; 2020 Dec 15; 409():115323. PubMed ID: 33176120
    [Abstract] [Full Text] [Related]

  • 3. Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice.
    Fu CL, Liu Y, Leng J, Zhang J, He YF, Chen C, Wang Z, Li W.
    Biomed Pharmacother; 2018 Nov 15; 107():867-877. PubMed ID: 30257399
    [Abstract] [Full Text] [Related]

  • 4. Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
    Du K, Ramachandran A, Weemhoff JL, Chavan H, Xie Y, Krishnamurthy P, Jaeschke H.
    Toxicol Sci; 2016 Dec 15; 154(2):214-226. PubMed ID: 27562556
    [Abstract] [Full Text] [Related]

  • 5. CXCL16 deficiency attenuates acetaminophen-induced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice.
    Wang H, Shao Y, Zhang S, Xie A, Ye Y, Shi L, Jin L, Pan X, Lin Z, Li X, Yang S.
    Acta Biochim Biophys Sin (Shanghai); 2017 Jun 01; 49(6):541-549. PubMed ID: 28459937
    [Abstract] [Full Text] [Related]

  • 6. Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.
    Mobasher MA, González-Rodriguez A, Santamaría B, Ramos S, Martín MÁ, Goya L, Rada P, Letzig L, James LP, Cuadrado A, Martín-Pérez J, Simpson KJ, Muntané J, Valverde AM.
    Cell Death Dis; 2013 May 09; 4(5):e626. PubMed ID: 23661004
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  • 7. Astaxanthin pretreatment attenuates acetaminophen-induced liver injury in mice.
    Zhang J, Zhang S, Bi J, Gu J, Deng Y, Liu C.
    Int Immunopharmacol; 2017 Apr 09; 45():26-33. PubMed ID: 28152447
    [Abstract] [Full Text] [Related]

  • 8. Hesperetin attenuated acetaminophen-induced hepatotoxicity by inhibiting hepatocyte necrosis and apoptosis, oxidative stress and inflammatory response via upregulation of heme oxygenase-1 expression.
    Wan J, Kuang G, Zhang L, Jiang R, Chen Y, He Z, Ye D.
    Int Immunopharmacol; 2020 Jun 09; 83():106435. PubMed ID: 32222641
    [Abstract] [Full Text] [Related]

  • 9. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes.
    Akakpo JY, Ramachandran A, Kandel SE, Ni HM, Kumer SC, Rumack BH, Jaeschke H.
    Hum Exp Toxicol; 2018 Dec 09; 37(12):1310-1322. PubMed ID: 29739258
    [Abstract] [Full Text] [Related]

  • 10. Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice.
    Kim YH, Hwang JH, Kim KS, Noh JR, Choi DH, Kim DK, Tadi S, Yim YH, Choi HS, Lee CH.
    J Hepatol; 2015 Jul 09; 63(1):75-82. PubMed ID: 25681557
    [Abstract] [Full Text] [Related]

  • 11. Simvastatin protects against acetaminophen-induced liver injury in mice.
    Liang H, Feng Y, Cui R, Qiu M, Zhang J, Liu C.
    Biomed Pharmacother; 2018 Feb 09; 98():916-924. PubMed ID: 29421861
    [Abstract] [Full Text] [Related]

  • 12. Mangiferin ameliorates acetaminophen-induced hepatotoxicity through APAP-Cys and JNK modulation.
    Chowdhury A, Lu J, Zhang R, Nabila J, Gao H, Wan Z, Adelusi Temitope I, Yin X, Sun Y.
    Biomed Pharmacother; 2019 Sep 09; 117():109097. PubMed ID: 31212128
    [Abstract] [Full Text] [Related]

  • 13. Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.
    Xie Y, Ramachandran A, Breckenridge DG, Liles JT, Lebofsky M, Farhood A, Jaeschke H.
    Toxicol Appl Pharmacol; 2015 Jul 01; 286(1):1-9. PubMed ID: 25818599
    [Abstract] [Full Text] [Related]

  • 14. Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
    Zhang JY, Song SD, Pang Q, Zhang RY, Wan Y, Yuan DW, Wu QF, Liu C.
    World J Gastroenterol; 2015 Apr 14; 21(14):4195-209. PubMed ID: 25892869
    [Abstract] [Full Text] [Related]

  • 15. Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.
    Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M, Preisinger C, Gassler N, Canbay AE, Luedde T, Davis RJ, Liedtke C, Trautwein C.
    Gastroenterology; 2016 Apr 14; 150(4):968-81. PubMed ID: 26708719
    [Abstract] [Full Text] [Related]

  • 16. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity.
    Dambach DM, Durham SK, Laskin JD, Laskin DL.
    Toxicol Appl Pharmacol; 2006 Mar 01; 211(2):157-65. PubMed ID: 16081117
    [Abstract] [Full Text] [Related]

  • 17. Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice.
    Ding Y, Li Q, Xu Y, Chen Y, Deng Y, Zhi F, Qian K.
    PLoS One; 2016 Mar 01; 11(5):e0154375. PubMed ID: 27144271
    [Abstract] [Full Text] [Related]

  • 18. Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.
    Xie Y, Williams CD, McGill MR, Lebofsky M, Ramachandran A, Jaeschke H.
    Toxicol Sci; 2013 Jan 01; 131(1):325-35. PubMed ID: 22986947
    [Abstract] [Full Text] [Related]

  • 19. Exogenous recombinant human thioredoxin-1 prevents acetaminophen-induced liver injury by scavenging oxidative stressors, restoring the thioredoxin-1 system and inhibiting receptor interacting protein-3 overexpression.
    Lee BW, Jeon BS, Yoon BI.
    J Appl Toxicol; 2018 Jul 01; 38(7):1008-1017. PubMed ID: 29512171
    [Abstract] [Full Text] [Related]

  • 20. Curcumin protects against acetaminophen-induced apoptosis in hepatic injury.
    Li G, Chen JB, Wang C, Xu Z, Nie H, Qin XY, Chen XM, Gong Q.
    World J Gastroenterol; 2013 Nov 14; 19(42):7440-6. PubMed ID: 24259976
    [Abstract] [Full Text] [Related]

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