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Journal Abstract Search

362 related items for PubMed ID: 31177401

  • 21. A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport.
    Zang X, Wang G, Cai Q, Zheng X, Zhang J, Chen Q, Wu B, Zhu X, Hao H, Zhou F.
    Drug Metab Dispos; 2018 May; 46(5):542-551. PubMed ID: 29523600
    [Abstract] [Full Text] [Related]

  • 22. Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells.
    Levrier C, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, Davis RA, Sadowski MC, Nelson CC.
    Cell Cycle; 2018 May; 17(5):652-668. PubMed ID: 28749250
    [Abstract] [Full Text] [Related]

  • 23. Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter-mediated drug resistance.
    Aoyama A, Katayama R, Oh-Hara T, Sato S, Okuno Y, Fujita N.
    Mol Cancer Ther; 2014 Dec; 13(12):2978-90. PubMed ID: 25313010
    [Abstract] [Full Text] [Related]

  • 24. Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics.
    Xu W, Xi B, Wu J, An H, Zhu J, Abassi Y, Feinstein SC, Gaylord M, Geng B, Yan H, Fan W, Sui M, Wang X, Xu X.
    Mol Cancer Ther; 2009 Dec; 8(12):3318-30. PubMed ID: 19996274
    [Abstract] [Full Text] [Related]

  • 25. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY.
    Cancer Res; 2004 Jul 01; 64(13):4621-8. PubMed ID: 15231674
    [Abstract] [Full Text] [Related]

  • 26. Morin reverses P-glycoprotein-mediated multidrug-resistance in KBChR-8-5 cancer cell lines.
    Zhao Y, Xu S, Hao W, Fu Y.
    Cell Biochem Funct; 2024 Jul 01; 42(5):e4083. PubMed ID: 38938150
    [Abstract] [Full Text] [Related]

  • 27. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
    Di Cesare E, Verrico A, Miele A, Giubettini M, Rovella P, Coluccia A, Famiglini V, La Regina G, Cundari E, Silvestri R, Lavia P.
    Oncotarget; 2017 Mar 21; 8(12):19738-19759. PubMed ID: 28160569
    [Abstract] [Full Text] [Related]

  • 28. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC.
    Cancer Res; 2001 Jul 15; 61(14):5480-5. PubMed ID: 11454695
    [Abstract] [Full Text] [Related]

  • 29. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
    Acharya BR, Chatterjee A, Ganguli A, Bhattacharya S, Chakrabarti G.
    Biochimie; 2014 Feb 15; 97():78-91. PubMed ID: 24113316
    [Abstract] [Full Text] [Related]

  • 30. Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells.
    Wang H, Vo T, Hajar A, Li S, Chen X, Parissenti AM, Brindley DN, Wang Z.
    BMC Cancer; 2014 Jan 22; 14():37. PubMed ID: 24447372
    [Abstract] [Full Text] [Related]

  • 31. Formulation and characterization of polyester/polycarbonate nanoparticles for delivery of a novel microtubule destabilizing agent.
    Mundra V, Lu Y, Danquah M, Li W, Miller DD, Mahato RI.
    Pharm Res; 2012 Nov 22; 29(11):3064-74. PubMed ID: 23054088
    [Abstract] [Full Text] [Related]

  • 32. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 22; 7(4):680-93. PubMed ID: 22311585
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  • 33. Novel microtubule inhibitor SQ overcomes multidrug resistance in MCF-7/ADR cells by inhibiting BCRP function and mediating apoptosis.
    Chang X, Liu Z, Cao S, Bian J, Zheng D, Wang N, Guan Q, Wu Y, Zhang W, Li Z, Zuo D.
    Toxicol Appl Pharmacol; 2022 Feb 01; 436():115883. PubMed ID: 35031325
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  • 34. Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells.
    Tripathi S, Srivastava G, Sharma A.
    Biochem Biophys Res Commun; 2016 Aug 05; 476(4):273-279. PubMed ID: 27233604
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  • 35. The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells.
    Brito DA, Rieder CL.
    Cell Motil Cytoskeleton; 2009 Aug 05; 66(8):437-47. PubMed ID: 18792104
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  • 36. MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
    Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y.
    Chem Biol Interact; 2020 May 25; 323():109074. PubMed ID: 32217108
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  • 37. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G.
    PLoS One; 2013 May 25; 8(10):e76286. PubMed ID: 24116100
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  • 38. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
    Królewska-Golińska K, Cieślak MJ, Sobczak M, Dolot R, Radzikowska-Cieciura E, Napiórkowska M, Wybrańska I, Nawrot B.
    Anticancer Agents Med Chem; 2019 May 25; 19(3):375-388. PubMed ID: 30465514
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  • 39. Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells.
    Wei JH, Seemann J.
    Mol Cancer Ther; 2010 Dec 25; 9(12):3375-85. PubMed ID: 21139045
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  • 40. JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.
    He Z, Wu J, Su X, Zhang Y, Pan L, Wei H, Fang Q, Li H, Wang DL, Sun FL.
    J Biol Chem; 2016 Feb 26; 291(9):4684-97. PubMed ID: 26710852
    [Abstract] [Full Text] [Related]

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