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Journal Abstract Search

447 related items for PubMed ID: 31179474

  • 1. Discovery, biological evaluation, structure-activity relationships and mechanism of action of pyrazolo[3,4-b]pyridin-6-one derivatives as a new class of anticancer agents.
    Guo Q, Luo Y, Zhai S, Jiang Z, Zhao C, Xu J, Wang L.
    Org Biomol Chem; 2019 Jun 26; 17(25):6201-6214. PubMed ID: 31179474
    [Abstract] [Full Text] [Related]

  • 2. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
    Guo Q, Zhang H, Deng Y, Zhai S, Jiang Z, Zhu D, Wang L.
    Eur J Med Chem; 2020 Jun 15; 196():112328. PubMed ID: 32320841
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.
    Khan I, Garikapati KR, Shaik AB, Makani VKK, Rahim A, Shareef MA, Reddy VG, Pal-Bhadra M, Kamal A, Kumar CG.
    Eur J Med Chem; 2018 Jan 20; 144():104-115. PubMed ID: 29268127
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 6. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G, Peng Z, Peng S, Qiu J, Li Y, Lan Y.
    Bioorg Med Chem Lett; 2018 Nov 01; 28(20):3350-3355. PubMed ID: 30197030
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation and molecular docking studies of a new series of chalcones containing naphthalene moiety as anticancer agents.
    Wang G, Qiu J, Xiao X, Cao A, Zhou F.
    Bioorg Chem; 2018 Feb 01; 76():249-257. PubMed ID: 29197743
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 13; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and bioevaluation of N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-amines as tubulin polymerization inhibitors with anti-angiogenic effects.
    Hao SY, Qi ZY, Wang S, Wang XR, Chen SW.
    Bioorg Med Chem; 2021 Feb 01; 31():115985. PubMed ID: 33421913
    [Abstract] [Full Text] [Related]

  • 11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 12. Discovery of a Series of Acridinones as Mechanism-Based Tubulin Assembly Inhibitors with Anticancer Activity.
    Magalhaes LG, Marques FB, da Fonseca MB, Rogério KR, Graebin CS, Andricopulo AD.
    PLoS One; 2016 Jun 09; 11(8):e0160842. PubMed ID: 27508497
    [Abstract] [Full Text] [Related]

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  • 14. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
    Sultana F, Reddy Bonam S, Reddy VG, Nayak VL, Akunuri R, Rani Routhu S, Alarifi A, Halmuthur MSK, Kamal A.
    Bioorg Chem; 2018 Feb 09; 76():1-12. PubMed ID: 29102724
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G, Peng Z, Li Y.
    Chem Pharm Bull (Tokyo); 2019 Jul 01; 67(7):725-728. PubMed ID: 30982797
    [Abstract] [Full Text] [Related]

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  • 17. Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
    Hu X, Li L, Zhang Q, Wang Q, Feng Z, Xu Y, Xia Y, Yu L.
    Bioorg Chem; 2020 Apr 01; 97():103695. PubMed ID: 32120073
    [Abstract] [Full Text] [Related]

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  • 19. Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer.
    Singh A, Fatima K, Srivastava A, Khwaja S, Priya D, Singh A, Mahajan G, Alam S, Saxena AK, Mondhe DM, Luqman S, Chanda D, Khan F, Negi AS.
    Chem Biol Drug Des; 2016 Nov 01; 88(5):625-634. PubMed ID: 27495835
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    Bioorg Chem; 2020 Jan 01; 95():103565. PubMed ID: 31927336
    [Abstract] [Full Text] [Related]

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