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PUBMED FOR HANDHELDS

Journal Abstract Search


103 related items for PubMed ID: 3118024

  • 1. Optimization and in vivo evaluations of a series of small, potent, and specific renin inhibitors containing a novel Leu-Val replacement.
    Dellaria JF, Maki RG, Bopp BA, Cohen J, Kleinert HD, Luly JR, Merits I, Plattner JJ, Stein HH.
    J Med Chem; 1987 Nov; 30(11):2137-44. PubMed ID: 3118024
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  • 2. New inhibitors of renin that contain novel phosphostatine Leu-Val replacements.
    Dellaria JF, Maki RG, Stein HH, Cohen J, Whittern D, Marsh K, Hoffman DJ, Plattner JJ, Perun TJ.
    J Med Chem; 1990 Feb; 33(2):534-42. PubMed ID: 2105396
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  • 3. Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.
    Luly JR, BaMaung N, Soderquist J, Fung AK, Stein H, Kleinert HD, Marcotte PA, Egan DA, Bopp B, Merits I.
    J Med Chem; 1988 Dec; 31(12):2264-76. PubMed ID: 3143009
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  • 4. Statine-containing dipeptide and tripeptide inhibitors of human renin.
    Kokubu T, Hiwada K, Nagae A, Murakami E, Morisawa Y, Yabe Y, Koike H, Iijima Y.
    Hypertension; 1986 Jun; 8(6 Pt 2):II1-5. PubMed ID: 3087874
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  • 5. Novel renin inhibitors containing (2S,3S,5S)-2-amino-1-cyclohexyl-6-methyl-3,5-heptanediol fragment as a transition-state mimic at the P1-P1' cleavage site.
    Yamada Y, Ando K, Ikemoto Y, Tada H, Shirakawa E, Inagaki E, Shibata S, Nakamura I, Hayashi Y, Ikegami K, Uchida I.
    Chem Pharm Bull (Tokyo); 1997 Oct; 45(10):1631-41. PubMed ID: 9353891
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  • 6. Highly potent and specific inhibitors of human renin.
    Sham HL, Stein H, Rempel CA, Cohen J, Plattner JJ.
    FEBS Lett; 1987 Aug 17; 220(2):299-301. PubMed ID: 3111889
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  • 7. Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.
    Iizuka K, Kamijo T, Harada H, Akahane K, Kubota T, Umeyama H, Ishida T, Kiso Y.
    J Med Chem; 1990 Oct 17; 33(10):2707-14. PubMed ID: 2120440
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  • 11. Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo.
    Thaisrivongs S, Pals DT, Harris DW, Kati WM, Turner SR.
    J Med Chem; 1986 Oct 17; 29(10):2088-93. PubMed ID: 3531518
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  • 12. Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond.
    Bolis G, Fung AK, Greer J, Kleinert HD, Marcotte PA, Perun TJ, Plattner JJ, Stein HH.
    J Med Chem; 1987 Oct 17; 30(10):1729-37. PubMed ID: 3309313
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  • 13. Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a structurally modified phenylalanine residue to impart proteolytic stability.
    Plattner JJ, Marcotte PA, Kleinert HD, Stein HH, Greer J, Bolis G, Fung AK, Bopp BA, Luly JR, Sham HL.
    J Med Chem; 1988 Dec 17; 31(12):2277-88. PubMed ID: 3143010
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  • 14. Renin inhibitors. Improvements in the stability and biological activity of small peptides containing novel Leu-Val replacements.
    Kleinert HD, Luly JR, Marcotte PA, Perun TJ, Plattner JJ, Stein H.
    FEBS Lett; 1988 Mar 28; 230(1-2):38-42. PubMed ID: 3280345
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  • 19. New human renin inhibitors containing an unnatural amino acid, norstatine.
    Iizuka K, Kamijo T, Kubota T, Akahane K, Umeyama H, Kiso Y.
    J Med Chem; 1988 Apr 28; 31(4):701-4. PubMed ID: 3127587
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  • 20. Enhanced potency dipeptide glycol renin inhibitors: studies in vitro and in the conscious rhesus.
    Hanson GJ, Baran JS, Lowrie HS, Sarussi SJ, Yang PC, Babler M, Bittner SE, Papaioannou SE, Walsh GM.
    Biochem Biophys Res Commun; 1987 Aug 14; 146(3):959-63. PubMed ID: 3304296
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