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608 related items for PubMed ID: 31185731

  • 1. Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation.
    Alsina KM, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Lehnart SE, Wehrens XHT.
    Circulation; 2019 Aug 20; 140(8):681-693. PubMed ID: 31185731
    [Abstract] [Full Text] [Related]

  • 2. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.
    Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, Wang G, Skapura D, Voigt N, Dobrev D, Wehrens XH.
    Cardiovasc Res; 2014 Jul 01; 103(1):178-87. PubMed ID: 24812280
    [Abstract] [Full Text] [Related]

  • 3. Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.
    Campbell HM, Quick AP, Abu-Taha I, Chiang DY, Kramm CF, Word TA, Brandenburg S, Hulsurkar M, Alsina KM, Liu HB, Martin B, Uhlenkamp D, Moore OM, Lahiri SK, Corradini E, Kamler M, Heck AJR, Lehnart SE, Dobrev D, Wehrens XHT.
    Circulation; 2020 Sep 22; 142(12):1159-1172. PubMed ID: 32683896
    [Abstract] [Full Text] [Related]

  • 4. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release.
    Chiang DY, Kongchan N, Beavers DL, Alsina KM, Voigt N, Neilson JR, Jakob H, Martin JF, Dobrev D, Wehrens XH, Li N.
    Circ Arrhythm Electrophysiol; 2014 Dec 22; 7(6):1214-22. PubMed ID: 25389315
    [Abstract] [Full Text] [Related]

  • 5. Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
    Shan J, Xie W, Betzenhauser M, Reiken S, Chen BX, Wronska A, Marks AR.
    Circ Res; 2012 Aug 31; 111(6):708-17. PubMed ID: 22828895
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice.
    Li N, Wang T, Wang W, Cutler MJ, Wang Q, Voigt N, Rosenbaum DS, Dobrev D, Wehrens XH.
    Circ Res; 2012 Feb 03; 110(3):465-70. PubMed ID: 22158709
    [Abstract] [Full Text] [Related]

  • 7. Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
    Mazzocchi G, Sommese L, Palomeque J, Felice JI, Di Carlo MN, Fainstein D, Gonzalez P, Contreras P, Skapura D, McCauley MD, Lascano EC, Negroni JA, Kranias EG, Wehrens XH, Valverde CA, Mattiazzi A.
    J Physiol; 2016 Jun 01; 594(11):3005-30. PubMed ID: 26695843
    [Abstract] [Full Text] [Related]

  • 8. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.
    Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XHT.
    Circulation; 2014 Mar 25; 129(12):1276-1285. PubMed ID: 24398018
    [Abstract] [Full Text] [Related]

  • 9. Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization.
    Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, Landstrom AP, Li N, Wang Q, Olivotto I, Dobrev D, Ackerman MJ, Wehrens XHT.
    J Am Coll Cardiol; 2013 Nov 19; 62(21):2010-9. PubMed ID: 23973696
    [Abstract] [Full Text] [Related]

  • 10. Oxidation- and CaMKII-mediated sarcoplasmic reticulum Ca(2+) leak triggers atrial fibrillation in aging.
    Guo X, Yuan S, Liu Z, Fang Q.
    J Cardiovasc Electrophysiol; 2014 Jun 19; 25(6):645-52. PubMed ID: 24576293
    [Abstract] [Full Text] [Related]

  • 11. Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation.
    Sood S, Chelu MG, van Oort RJ, Skapura D, Santonastasi M, Dobrev D, Wehrens XH.
    Heart Rhythm; 2008 Jul 19; 5(7):1047-54. PubMed ID: 18598963
    [Abstract] [Full Text] [Related]

  • 12. Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.
    Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, Sun Q, Wieland T, Ravens U, Nattel S, Wehrens XH, Dobrev D.
    Circulation; 2012 May 01; 125(17):2059-70. PubMed ID: 22456474
    [Abstract] [Full Text] [Related]

  • 13. The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency.
    Kim K, Blackwell DJ, Yuen SL, Thorpe MP, Johnston JN, Cornea RL, Knollmann BC.
    J Mol Cell Cardiol; 2023 Jul 01; 180():1-9. PubMed ID: 37080450
    [Abstract] [Full Text] [Related]

  • 14. Activation of endogenous protein phosphatase 1 enhances the calcium sensitivity of the ryanodine receptor type 2 in murine ventricular cardiomyocytes.
    Potenza DM, Janicek R, Fernandez-Tenorio M, Niggli E.
    J Physiol; 2020 Mar 01; 598(6):1131-1150. PubMed ID: 31943206
    [Abstract] [Full Text] [Related]

  • 15. Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts.
    Zhang Y, Qi Y, Li JJ, He WJ, Gao XH, Zhang Y, Sun X, Tong J, Zhang J, Deng XL, Du XJ, Xie W.
    Cardiovasc Res; 2021 Mar 21; 117(4):1091-1102. PubMed ID: 32531044
    [Abstract] [Full Text] [Related]

  • 16. Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
    Bai Y, Jones PP, Guo J, Zhong X, Clark RB, Zhou Q, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Semeniuk L, Guo A, Song LS, Duff HJ, Chen SR.
    Circ Res; 2013 Aug 16; 113(5):517-26. PubMed ID: 23856523
    [Abstract] [Full Text] [Related]

  • 17. Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
    Valverde CA, Mazzocchi G, Di Carlo MN, Ciocci Pardo A, Salas N, Ragone MI, Felice JI, Cely-Ortiz A, Consolini AE, Portiansky E, Mosca S, Kranias EG, Wehrens XHT, Mattiazzi A.
    Cardiovasc Res; 2019 Mar 01; 115(3):556-569. PubMed ID: 30169578
    [Abstract] [Full Text] [Related]

  • 18. Defective cardiac ryanodine receptor regulation during atrial fibrillation.
    Vest JA, Wehrens XH, Reiken SR, Lehnart SE, Dobrev D, Chandra P, Danilo P, Ravens U, Rosen MR, Marks AR.
    Circulation; 2005 Apr 26; 111(16):2025-32. PubMed ID: 15851612
    [Abstract] [Full Text] [Related]

  • 19. CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
    Di Carlo MN, Said M, Ling H, Valverde CA, De Giusti VC, Sommese L, Palomeque J, Aiello EA, Skapura DG, Rinaldi G, Respress JL, Brown JH, Wehrens XH, Salas MA, Mattiazzi A.
    J Mol Cell Cardiol; 2014 Sep 26; 74():274-83. PubMed ID: 24949568
    [Abstract] [Full Text] [Related]

  • 20. Regulation of sarcoplasmic reticulum Ca2+ release by serine-threonine phosphatases in the heart.
    Terentyev D, Hamilton S.
    J Mol Cell Cardiol; 2016 Dec 26; 101():156-164. PubMed ID: 27585747
    [Abstract] [Full Text] [Related]

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