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Journal Abstract Search

253 related items for PubMed ID: 31199681

  • 1.
    ; . PubMed ID:
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  • 2. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N, Son J, Craig-Lucas AB, John CL, Breech KJ, Podolsky MA, Glick AB.
    Proc Natl Acad Sci U S A; 2017 Sep 12; 114(37):9900-9905. PubMed ID: 28847931
    [Abstract] [Full Text] [Related]

  • 3. Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.
    Pinkaew D, Chattopadhyay A, King MD, Chunhacha P, Liu Z, Stevenson HL, Chen Y, Sinthujaroen P, McDougal OM, Fujise K.
    Nat Commun; 2017 May 26; 8(1):18. PubMed ID: 28550308
    [Abstract] [Full Text] [Related]

  • 4. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.
    Cell Signal; 2013 Nov 26; 25(11):2136-46. PubMed ID: 23816533
    [Abstract] [Full Text] [Related]

  • 5. Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands.
    Feldman HC, Tong M, Wang L, Meza-Acevedo R, Gobillot TA, Lebedev I, Gliedt MJ, Hari SB, Mitra AK, Backes BJ, Papa FR, Seeliger MA, Maly DJ.
    ACS Chem Biol; 2016 Aug 19; 11(8):2195-205. PubMed ID: 27227314
    [Abstract] [Full Text] [Related]

  • 6. A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress.
    Li X, Sun S, Appathurai S, Sundaram A, Plumb R, Mariappan M.
    Cell Rep; 2020 Dec 29; 33(13):108563. PubMed ID: 33378667
    [Abstract] [Full Text] [Related]

  • 7. Emerging roles for the ER stress sensor IRE1α in metabolic regulation and disease.
    Huang S, Xing Y, Liu Y.
    J Biol Chem; 2019 Dec 06; 294(49):18726-18741. PubMed ID: 31666338
    [Abstract] [Full Text] [Related]

  • 8. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A, Wang H, Li Y, Wang X, Chen D, Wu Z.
    Viruses; 2017 Aug 23; 9(9):. PubMed ID: 28832521
    [Abstract] [Full Text] [Related]

  • 9. PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response.
    Jwa M, Chang P.
    Nat Cell Biol; 2012 Nov 23; 14(11):1223-30. PubMed ID: 23103912
    [Abstract] [Full Text] [Related]

  • 10. Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis.
    Li Y, Huang S, Wang J, Dai J, Cai J, Yan S, Huang Z, He S, Wang P, Liu J, Liu Y.
    J Biol Chem; 2022 Jun 23; 298(6):101997. PubMed ID: 35500653
    [Abstract] [Full Text] [Related]

  • 11. Disordered regions in the IRE1α ER lumenal domain mediate its stress-induced clustering.
    Kettel P, Marosits L, Spinetti E, Rechberger M, Giannini C, Radler P, Niedermoser I, Fischer I, Versteeg GA, Loose M, Covino R, Karagöz GE.
    EMBO J; 2024 Oct 23; 43(20):4668-4698. PubMed ID: 39232130
    [Abstract] [Full Text] [Related]

  • 12. Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells.
    Ota A, Wang Y.
    J Biol Chem; 2012 Feb 24; 287(9):6266-74. PubMed ID: 22199355
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.
    Biochem Pharmacol; 2016 Jun 01; 109():27-47. PubMed ID: 27059255
    [Abstract] [Full Text] [Related]

  • 14. Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.
    Bouchecareilh M, Higa A, Fribourg S, Moenner M, Chevet E.
    FASEB J; 2011 Sep 01; 25(9):3115-29. PubMed ID: 21680894
    [Abstract] [Full Text] [Related]

  • 15. An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation.
    Ricci D, Tutton S, Marrocco I, Ying M, Blumenthal D, Eletto D, Vargas J, Boyle S, Fazelinia H, Qian L, Suresh K, Taylor D, Paton JC, Paton AW, Tang CA, Hu CA, Radhakrishnan R, Gidalevitz T, Argon Y.
    J Biol Chem; 2021 Sep 01; 296():100781. PubMed ID: 34000298
    [Abstract] [Full Text] [Related]

  • 16. SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells.
    Nguyen LC, Renner DM, Silva D, Yang D, Parenti NA, Medina KM, Nicolaescu V, Gula H, Drayman N, Valdespino A, Mohamed A, Dann C, Wannemo K, Robinson-Mailman L, Gonzalez A, Stock L, Cao M, Qiao Z, Moellering RE, Tay S, Randall G, Beers MF, Rosner MR, Oakes SA, Weiss SR.
    mBio; 2022 Oct 26; 13(5):e0241522. PubMed ID: 36125275
    [Abstract] [Full Text] [Related]

  • 17. Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity.
    Orsi A, van Anken E, Vitale M, Zamai M, Caiolfa VR, Sitia R, Bakunts A.
    Life Sci Alliance; 2024 Sep 26; 7(9):. PubMed ID: 38886017
    [Abstract] [Full Text] [Related]

  • 18. A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress.
    Han D, Upton JP, Hagen A, Callahan J, Oakes SA, Papa FR.
    Biochem Biophys Res Commun; 2008 Jan 25; 365(4):777-83. PubMed ID: 18035051
    [Abstract] [Full Text] [Related]

  • 19. Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.
    Sepulveda D, Rojas-Rivera D, Rodríguez DA, Groenendyk J, Köhler A, Lebeaupin C, Ito S, Urra H, Carreras-Sureda A, Hazari Y, Vasseur-Cognet M, Ali MMU, Chevet E, Campos G, Godoy P, Vaisar T, Bailly-Maitre B, Nagata K, Michalak M, Sierralta J, Hetz C.
    Mol Cell; 2018 Jan 18; 69(2):238-252.e7. PubMed ID: 29351844
    [Abstract] [Full Text] [Related]

  • 20. Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells.
    Yuan J, Yao C, Tang J, Liu Y, Huang C, Yu S, Wei H, Han Y, Chen G.
    Toxicology; 2021 Oct 18; 462():152962. PubMed ID: 34560123
    [Abstract] [Full Text] [Related]

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