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155 related items for PubMed ID: 31203647

  • 1. Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways.
    He Y, Cao X, Kong Y, Wang S, Xia Y, Bi R, Liu J.
    Hum Exp Toxicol; 2019 Oct; 38(10):1132-1144. PubMed ID: 31203647
    [Abstract] [Full Text] [Related]

  • 2. Alantolactone induces apoptosis and suppresses migration in MCF‑7 human breast cancer cells via the p38 MAPK, NF‑κB and Nrf2 signaling pathways.
    Liu J, Liu M, Wang S, He Y, Huo Y, Yang Z, Cao X.
    Int J Mol Med; 2018 Oct; 42(4):1847-1856. PubMed ID: 30015828
    [Abstract] [Full Text] [Related]

  • 3. Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
    He W, Cao P, Xia Y, Hong L, Zhang T, Shen X, Zheng P, Shen H, Zhao Y, Zou P.
    Free Radic Res; 2019 Jan; 53(1):104-114. PubMed ID: 30668191
    [Abstract] [Full Text] [Related]

  • 4. Antitumor activity of alantolactone in lung cancer cell lines NCI-H1299 and Anip973.
    Liu J, Yang Z, Kong Y, He Y, Xu Y, Cao X.
    J Food Biochem; 2019 Sep; 43(9):e12972. PubMed ID: 31489665
    [Abstract] [Full Text] [Related]

  • 5. Alantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades.
    Wang X, Yu Z, Wang C, Cheng W, Tian X, Huo X, Wang Y, Sun C, Feng L, Xing J, Lan Y, Sun D, Hou Q, Zhang B, Ma X, Zhang B.
    J Exp Clin Cancer Res; 2017 Jul 12; 36(1):93. PubMed ID: 28701209
    [Abstract] [Full Text] [Related]

  • 6. Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells.
    Chun J, Choi RJ, Khan S, Lee DS, Kim YC, Nam YJ, Lee DU, Kim YS.
    Int Immunopharmacol; 2012 Dec 12; 14(4):375-83. PubMed ID: 22940184
    [Abstract] [Full Text] [Related]

  • 7. Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion.
    Wei W, Huang H, Zhao S, Liu W, Liu CX, Chen L, Li JM, Wu YL, Yan H.
    Apoptosis; 2013 Sep 12; 18(9):1060-70. PubMed ID: 23613107
    [Abstract] [Full Text] [Related]

  • 8. Alantolactone exhibits antiproliferative and apoptosis-promoting properties in colon cancer model via activation of the MAPK-JNK/c-Jun signaling pathway.
    Ren Y, Lv C, Zhang J, Zhang B, Yue B, Luo X, Yu Z, Wang H, Ren J, Wang Z, Dou W.
    Mol Cell Biochem; 2021 Dec 12; 476(12):4387-4403. PubMed ID: 34460036
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway.
    Cui L, Bu W, Song J, Feng L, Xu T, Liu D, Ding W, Wang J, Li C, Ma B, Luo Y, Jiang Z, Wang C, Chen J, Hou J, Yan H, Yang L, Jia X.
    Arch Pharm Res; 2018 Mar 12; 41(3):299-313. PubMed ID: 29214600
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/β- Catenin Signaling.
    Wang Z, Hu Q, Chen H, Shi L, He M, Liu H, Li T, Lü M, Deng M, Luo G.
    Anticancer Agents Med Chem; 2021 Mar 12; 21(18):2525-2535. PubMed ID: 33438562
    [Abstract] [Full Text] [Related]

  • 11. Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction.
    Khan M, Yi F, Rasul A, Li T, Wang N, Gao H, Gao R, Ma T.
    IUBMB Life; 2012 Sep 12; 64(9):783-94. PubMed ID: 22837216
    [Abstract] [Full Text] [Related]

  • 12. Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells.
    Chun J, Li RJ, Cheng MS, Kim YS.
    Cancer Lett; 2015 Feb 01; 357(1):393-403. PubMed ID: 25434800
    [Abstract] [Full Text] [Related]

  • 13. Oldenlandia diffusa suppresses metastatic potential through inhibiting matrix metalloproteinase-9 and intercellular adhesion molecule-1 expression via p38 and ERK1/2 MAPK pathways and induces apoptosis in human breast cancer MCF-7 cells.
    Chung TW, Choi H, Lee JM, Ha SH, Kwak CH, Abekura F, Park JY, Chang YC, Ha KT, Cho SH, Chang HW, Lee YC, Kim CH.
    J Ethnopharmacol; 2017 Jan 04; 195():309-317. PubMed ID: 27876502
    [Abstract] [Full Text] [Related]

  • 14. Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells.
    Yan YY, Zhang Q, Zhang B, Yang B, Lin NM.
    Nat Prod Res; 2020 Sep 04; 34(17):2539-2544. PubMed ID: 30661396
    [Abstract] [Full Text] [Related]

  • 15. Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells.
    Ding Y, Wang H, Niu J, Luo M, Gou Y, Miao L, Zou Z, Cheng Y.
    Int J Mol Sci; 2016 Apr 14; 17(4):558. PubMed ID: 27089328
    [Abstract] [Full Text] [Related]

  • 16. Semisynthesis, an Anti-Inflammatory Effect of Derivatives of 1β-Hydroxy Alantolactone from Inula britannica.
    Chen L, Zhang JP, Liu X, Tang JJ, Xiang P, Ma XM.
    Molecules; 2017 Oct 27; 22(11):. PubMed ID: 29077042
    [Abstract] [Full Text] [Related]

  • 17. Alantolactone exhibits selective antitumor effects in HELA human cervical cancer cells by inhibiting cell migration and invasion, G2/M cell cycle arrest, mitochondrial mediated apoptosis and targeting Nf-kB signalling pathway.
    Zhang Y, Zhao Y, Ran Y, Guo J, Cui H, Liu S.
    J BUON; 2019 Oct 27; 24(6):2310-2315. PubMed ID: 31983099
    [Abstract] [Full Text] [Related]

  • 18. 2α-Hydroxyeudesma-4,11(13)-Dien-8β,12-Olide Isolated from Inula britannica Induces Apoptosis in Diffuse Large B-cell Lymphoma Cells.
    Jang DK, Lee IS, Shin HS, Yoo HM.
    Biomolecules; 2020 Feb 18; 10(2):. PubMed ID: 32085513
    [Abstract] [Full Text] [Related]

  • 19. Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
    He R, Shi X, Zhou M, Zhao Y, Pan S, Zhao C, Guo X, Wang M, Li X, Qin R.
    Toxicol Appl Pharmacol; 2018 Oct 01; 356():159-171. PubMed ID: 30086361
    [Abstract] [Full Text] [Related]

  • 20. Alantolactone Induced Apoptosis and DNA Damage of Cervical Cancer through ATM/CHK2 Signaling Pathway.
    Zhang Y, Li H, Wei Y, Li L.
    Biol Pharm Bull; 2024 Oct 01; 47(7):1255-1264. PubMed ID: 38972750
    [Abstract] [Full Text] [Related]

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