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99 related items for PubMed ID: 3120474

  • 1. Orally active alpha-ketohydroxypyridine iron chelators: effects on iron and other metal mobilisations.
    Kontoghiorghes GJ.
    Acta Haematol; 1987; 78(2-3):212-6. PubMed ID: 3120474
    [Abstract] [Full Text] [Related]

  • 2. Orally active alpha-ketohydroxypyridine iron chelators: studies in mice.
    Kontoghiorghes GJ.
    Mol Pharmacol; 1986 Dec; 30(6):670-3. PubMed ID: 3785144
    [Abstract] [Full Text] [Related]

  • 3. Selection of a new generation of orally active alpha-ketohydroxypyridine iron chelators intended for use in the treatment of iron overload.
    Kontoghiorghes GJ, Barr J, Nortey P, Sheppard L.
    Am J Hematol; 1993 Apr; 42(4):340-9. PubMed ID: 8493983
    [Abstract] [Full Text] [Related]

  • 4. Dose response studies using desferrioxamine and orally active chelators in a mouse model.
    Kontoghiorghes GJ.
    Scand J Haematol; 1986 Jul; 37(1):63-70. PubMed ID: 3764334
    [Abstract] [Full Text] [Related]

  • 5. In vivo evaluation of hydroxypyridone iron chelators in a mouse model.
    Gyparaki M, Porter JB, Hirani S, Streater M, Hider RC, Huehns ER.
    Acta Haematol; 1987 Jul; 78(2-3):217-21. PubMed ID: 3120475
    [Abstract] [Full Text] [Related]

  • 6. Effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages.
    Brock JH, Licéaga J, Arthur HM, Kontoghiorghes GJ.
    Am J Hematol; 1990 May; 34(1):21-5. PubMed ID: 2327400
    [Abstract] [Full Text] [Related]

  • 7. Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats.
    Kontoghiorghes GJ, Sheppard L, Hoffbrand AV, Charalambous J, Tikerpae J, Pippard MJ.
    J Clin Pathol; 1987 Apr; 40(4):404-8. PubMed ID: 3584483
    [Abstract] [Full Text] [Related]

  • 8. Orally active alpha-ketohydroxy pyridine iron chelators intended for clinical use: in vivo studies in rabbits.
    Kontoghiorghes GJ, Hoffbrand AV.
    Br J Haematol; 1986 Apr; 62(4):607-13. PubMed ID: 3964556
    [Abstract] [Full Text] [Related]

  • 9. New synthetic approach and iron chelating studies of 1-alkyl-2-methyl-3-hydroxypyrid-4-ones.
    Kontoghiorghes GJ, Sheppard L, Chambers S.
    Arzneimittelforschung; 1987 Oct; 37(10):1099-102. PubMed ID: 3435580
    [Abstract] [Full Text] [Related]

  • 10. Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs.
    Kontoghiorghes GJ.
    Toxicol Lett; 1995 Oct; 80(1-3):1-18. PubMed ID: 7482575
    [Abstract] [Full Text] [Related]

  • 11. In vivo iron mobilisation evaluation of hydroxypyridinones in 59Fe-ferritin-loaded rat model.
    Liu ZD, Lu SL, Hider RC.
    Biochem Pharmacol; 1999 Mar 01; 57(5):559-66. PubMed ID: 9952320
    [Abstract] [Full Text] [Related]

  • 12. The effect of 2,4-dihydroxypyridine-N-oxide, a new orally active iron chelator, on iron excretion in mice.
    Kontoghiorghes GJ.
    Clin Chim Acta; 1987 Mar 16; 163(2):137-41. PubMed ID: 3568416
    [Abstract] [Full Text] [Related]

  • 13. Chelators affecting iron absorption in mice.
    Kontoghiorghes GJ.
    Arzneimittelforschung; 1990 Dec 16; 40(12):1332-5. PubMed ID: 2095129
    [Abstract] [Full Text] [Related]

  • 14. PCTH: a novel orally active chelator of the aroylhydrazone class that induces iron excretion from mice.
    Wong CS, Kwok JC, Richardson DR.
    Biochim Biophys Acta; 2004 Dec 24; 1739(1):70-80. PubMed ID: 15607119
    [Abstract] [Full Text] [Related]

  • 15. Studies of in vivo iron mobilization by chelators in the ferrocene-loaded rat.
    Florence A, Ward RJ, Peters TJ, Crichton RR.
    Biochem Pharmacol; 1992 Sep 25; 44(6):1023-7. PubMed ID: 1417929
    [Abstract] [Full Text] [Related]

  • 16. The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
    Jeremy JY, Kontoghiorghes GJ, Hoffbrand AV, Dandona P.
    Biochem J; 1988 Aug 15; 254(1):239-44. PubMed ID: 3140797
    [Abstract] [Full Text] [Related]

  • 17. Site specificity of iron removal from transferrin by alpha-ketohydroxypyridine chelators.
    Kontoghiorghes GJ, Evans RW.
    FEBS Lett; 1985 Sep 09; 189(1):141-4. PubMed ID: 4029396
    [Abstract] [Full Text] [Related]

  • 18. Iron mobilisation from lactoferrin by chelators at physiological pH.
    Kontoghiorghes GJ.
    Biochim Biophys Acta; 1986 Jun 19; 882(2):267-70. PubMed ID: 3708002
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and biological evaluation of aromatic ester prodrugs of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41) as orally active iron chelators.
    Liu ZD, Liu DY, Lu SL, Hider RC.
    Arzneimittelforschung; 2000 May 19; 50(5):461-70. PubMed ID: 10858874
    [Abstract] [Full Text] [Related]

  • 20. Biliary excretion of plasma non-transferrin-bound iron in rats: pathogenetic importance in iron-overload disorders.
    Brissot P, Zanninelli G, Guyader D, Zeind J, Gollan J.
    Am J Physiol; 1994 Jul 19; 267(1 Pt 1):G135-42. PubMed ID: 8048526
    [Abstract] [Full Text] [Related]

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