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358 related items for PubMed ID: 31217332

  • 1. Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer's Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion.
    Ortega-Martinez S, Palla N, Zhang X, Lipman E, Sisodia SS.
    J Neurosci; 2019 Aug 21; 39(34):6766-6780. PubMed ID: 31217332
    [Abstract] [Full Text] [Related]

  • 2. Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.
    Veeraraghavalu K, Choi SH, Zhang X, Sisodia SS.
    Mol Neurodegener; 2013 Oct 20; 8():41. PubMed ID: 24138759
    [Abstract] [Full Text] [Related]

  • 3. Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells.
    Veeraraghavalu K, Sisodia SS.
    Proc Natl Acad Sci U S A; 2013 May 28; 110(22):9148-53. PubMed ID: 23674689
    [Abstract] [Full Text] [Related]

  • 4. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation.
    Choi SH, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM, Sisodia SS.
    Neuron; 2008 Aug 28; 59(4):568-80. PubMed ID: 18760694
    [Abstract] [Full Text] [Related]

  • 5. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA.
    Exp Neurol; 2004 Aug 28; 188(2):224-37. PubMed ID: 15246822
    [Abstract] [Full Text] [Related]

  • 6. Expression of familial Alzheimer's disease-linked human presenilin 1 variants impair enrichment-induced adult hippocampal neurogenesis.
    Veeraraghavalu K, Choi SH, Sisodia SS.
    Neurodegener Dis; 2010 Aug 28; 7(1-3):46-9. PubMed ID: 20160458
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease.
    Biscaro B, Lindvall O, Tesco G, Ekdahl CT, Nitsch RM.
    Neurodegener Dis; 2012 Aug 28; 9(4):187-98. PubMed ID: 22584394
    [Abstract] [Full Text] [Related]

  • 8. Alzheimer's disease-causing presenilin-1 mutations have deleterious effects on mitochondrial function.
    Han J, Park H, Maharana C, Gwon AR, Park J, Baek SH, Bae HG, Cho Y, Kim HK, Sul JH, Lee J, Kim E, Kim J, Cho Y, Park S, Palomera LF, Arumugam TV, Mattson MP, Jo DG.
    Theranostics; 2021 Aug 28; 11(18):8855-8873. PubMed ID: 34522215
    [Abstract] [Full Text] [Related]

  • 9. Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling.
    Veeraraghavalu K, Choi SH, Zhang X, Sisodia SS.
    J Neurosci; 2010 May 19; 30(20):6903-15. PubMed ID: 20484632
    [Abstract] [Full Text] [Related]

  • 10. Expression of a familial Alzheimer's disease-linked presenilin-1 variant enhances perforant pathway lesion-induced neuronal loss in the entorhinal cortex.
    Lazarov O, Peterson LD, Peterson DA, Sisodia SS.
    J Neurosci; 2006 Jan 11; 26(2):429-34. PubMed ID: 16407539
    [Abstract] [Full Text] [Related]

  • 11. Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
    Malik B, Currais A, Soriano S.
    J Neurochem; 2008 Jul 11; 106(2):912-6. PubMed ID: 18466334
    [Abstract] [Full Text] [Related]

  • 12. Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice.
    Kiyota T, Morrison CM, Tu G, Dyavarshetty B, Weir RA, Zhang G, Xiong H, Gendelman HE.
    Brain Behav Immun; 2015 Oct 11; 49():311-21. PubMed ID: 26112421
    [Abstract] [Full Text] [Related]

  • 13. Late-life environmental enrichment preserves short-term memory and may attenuate microglia in male APP/PS1 mice.
    Stuart KE, King AE, King NE, Collins JM, Vickers JC, Ziebell JM.
    Neuroscience; 2019 Jun 01; 408():282-292. PubMed ID: 30999032
    [Abstract] [Full Text] [Related]

  • 14. Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory.
    Bonds JA, Kuttner-Hirshler Y, Bartolotti N, Tobin MK, Pizzi M, Marr R, Lazarov O.
    PLoS One; 2015 Jun 01; 10(6):e0131266. PubMed ID: 26098332
    [Abstract] [Full Text] [Related]

  • 15. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease.
    Zhang C, McNeil E, Dressler L, Siman R.
    Exp Neurol; 2007 Mar 01; 204(1):77-87. PubMed ID: 17070803
    [Abstract] [Full Text] [Related]

  • 16. Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2.
    Dhaliwal J, Kannangara TS, Vaculik M, Xue Y, Kumar KL, Maione A, Béïque JC, Shen J, Lagace DC.
    Sci Rep; 2018 Dec 18; 8(1):17931. PubMed ID: 30560948
    [Abstract] [Full Text] [Related]

  • 17. L-3-n-Butylphthalide Regulates Proliferation, Migration, and Differentiation of Neural Stem Cell In Vitro and Promotes Neurogenesis in APP/PS1 Mouse Model by Regulating BDNF/TrkB/CREB/Akt Pathway.
    Lei H, Zhang Y, Huang L, Xu S, Li J, Yang L, Wang L, Xing C, Wang X, Peng Y.
    Neurotox Res; 2018 Oct 18; 34(3):477-488. PubMed ID: 29728920
    [Abstract] [Full Text] [Related]

  • 18. Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
    Sun X, Beglopoulos V, Mattson MP, Shen J.
    Neurodegener Dis; 2005 Oct 18; 2(1):6-15. PubMed ID: 16908998
    [Abstract] [Full Text] [Related]

  • 19. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.
    Kaneko H, Kakita A, Kasuga K, Nozaki H, Ishikawa A, Miyashita A, Kuwano R, Ito G, Iwatsubo T, Takahashi H, Nishizawa M, Onodera O, Sisodia SS, Ikeuchi T.
    J Neurosci; 2007 Nov 28; 27(48):13092-7. PubMed ID: 18045903
    [Abstract] [Full Text] [Related]

  • 20. Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice.
    Demars M, Hu YS, Gadadhar A, Lazarov O.
    J Neurosci Res; 2010 Aug 01; 88(10):2103-17. PubMed ID: 20209626
    [Abstract] [Full Text] [Related]

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