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94 related items for PubMed ID: 3121734

  • 1. The effect of dihydrofolate reductase-mediated gene amplification on the expression of transfected immunoglobulin genes.
    Dorai H, Moore GP.
    J Immunol; 1987 Dec 15; 139(12):4232-41. PubMed ID: 3121734
    [Abstract] [Full Text] [Related]

  • 2. Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: stability in the absence of selective pressure.
    Kim NS, Kim SJ, Lee GM.
    Biotechnol Bioeng; 1998 Dec 20; 60(6):679-88. PubMed ID: 10099478
    [Abstract] [Full Text] [Related]

  • 3. Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
    Kim SJ, Kim NS, Ryu CJ, Hong HJ, Lee GM.
    Biotechnol Bioeng; 1998 Apr 05; 58(1):73-84. PubMed ID: 10099263
    [Abstract] [Full Text] [Related]

  • 4. Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
    Kim SJ, Lee GM.
    Biotechnol Bioeng; 1999 Sep 20; 64(6):741-9. PubMed ID: 10417224
    [Abstract] [Full Text] [Related]

  • 5. Analysis of co-transfected expression vectors amplified by methotrexate selection in rat-1 cells.
    Ricketts MH, Vandenplas S, van der Merwe MJ, Bellstedt DU, North HM.
    Eur J Cell Biol; 1991 Oct 20; 56(1):43-8. PubMed ID: 1666042
    [Abstract] [Full Text] [Related]

  • 6. Overexpression of human prothrombin in permanent cell lines using a dominant selection/amplification fusion marker.
    Herlitschka SE, Falkner FG, Schlokat U, Dorner F.
    Protein Expr Purif; 1996 Nov 20; 8(3):358-64. PubMed ID: 8936598
    [Abstract] [Full Text] [Related]

  • 7. Gene mutations and alternate RNA splicing result in truncated Ig L chains in human gamma H chain disease.
    Cogné M, Bakhshi A, Korsmeyer SJ, Guglielmi P.
    J Immunol; 1988 Sep 01; 141(5):1738-44. PubMed ID: 3137264
    [Abstract] [Full Text] [Related]

  • 8. Amplification of the human alpha-globin gene enhances its expression.
    Lau YF, Lin CC, Kan YW.
    Trans Assoc Am Physicians; 1983 Sep 01; 96():93-102. PubMed ID: 6679967
    [Abstract] [Full Text] [Related]

  • 9. Regulation of dihydrofolate reductase in human breast cancer cells and in mutant hamster cells transfected with a human dihydrofolate reductase minigene.
    Cowan KH, Goldsmith ME, Ricciardone MD, Levine R, Rubalcaba E, Jolivet J.
    Mol Pharmacol; 1986 Jul 01; 30(1):69-76. PubMed ID: 3724746
    [Abstract] [Full Text] [Related]

  • 10. Gene amplification and drug resistance in mammalian cells.
    Schimke RT, Brown PC, Kaufman RJ.
    Natl Cancer Inst Monogr; 1982 Jul 01; 60():79-86. PubMed ID: 7121575
    [Abstract] [Full Text] [Related]

  • 11. Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells.
    Gandor C, Leist C, Fiechter A, Asselbergs FA.
    FEBS Lett; 1995 Dec 27; 377(3):290-4. PubMed ID: 8549740
    [Abstract] [Full Text] [Related]

  • 12. [Localization of dihydrofolate reductase amplified genes in Chinese hamster cells resistant to methotrexate].
    Mukhamedkhanova FS, Kuznetsova NN, Nuridzhaniants SS, Abdurkarimov AA.
    Genetika; 1987 Sep 27; 23(9):1588-94. PubMed ID: 3692154
    [Abstract] [Full Text] [Related]

  • 13. Amplification and expression of foreign genes in cells producing polyoma virus large T-antigen.
    Pellegrini S, Basilico C.
    Oncogene Res; 1987 Jun 27; 1(1):23-41. PubMed ID: 2835727
    [Abstract] [Full Text] [Related]

  • 14. Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.
    Kim NS, Byun TH, Lee GM.
    Biotechnol Prog; 2001 Jun 27; 17(1):69-75. PubMed ID: 11170482
    [Abstract] [Full Text] [Related]

  • 15. [Significantly improvement of antibody expression level in CHO cells through downregulation of the DHFR gene in expression vector].
    Bai Y, Wang Y, Zhang HR, Zhou LJ, Lu YQ, Yu LZ.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2003 Jan 27; 19(1):62-4, 67. PubMed ID: 15132910
    [Abstract] [Full Text] [Related]

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  • 17. Co-expression and amplification of dihydrofolate reductase cDNA and the Escherichia coli XGPRT gene in Chinese hamster ovary cells.
    Ringold G, Dieckmann B, Lee F.
    J Mol Appl Genet; 1981 Jan 27; 1(3):165-75. PubMed ID: 6180118
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
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  • 19. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.
    Banerjee D, Zhao SC, Tong Y, Steinherz J, Gritsman K, Bertino JR.
    Cancer Gene Ther; 1994 Sep 27; 1(3):181-4. PubMed ID: 7621249
    [Abstract] [Full Text] [Related]

  • 20. Gene transfer of immunoglobulin light chain restores heavy chain secretion.
    Pepe VH, Sonenshein GE, Yoshimura MI, Shulman MJ.
    J Immunol; 1986 Oct 01; 137(7):2367-72. PubMed ID: 3093573
    [Abstract] [Full Text] [Related]

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