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1038 related items for PubMed ID: 31230505

  • 1. Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway.
    Zhu Y, Zhong Y, Long X, Zhu Z, Zhou Y, Ye H, Zeng X, Zheng X.
    Pharm Biol; 2019 Dec; 57(1):412-423. PubMed ID: 31230505
    [Abstract] [Full Text] [Related]

  • 2. GOLPH3 inhibition reverses oxaliplatin resistance of colon cancer cells via suppression of PI3K/AKT/mTOR pathway.
    Yu T, An Q, Cao XL, Yang H, Cui J, Li ZJ, Xiao G.
    Life Sci; 2020 Nov 01; 260():118294. PubMed ID: 32818544
    [Abstract] [Full Text] [Related]

  • 3. Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
    Yao W, Lin Z, Shi P, Chen B, Wang G, Huang J, Sui Y, Liu Q, Li S, Lin X, Liu Q, Yao H.
    Biochem Pharmacol; 2020 Jan 01; 171():113680. PubMed ID: 31669234
    [Abstract] [Full Text] [Related]

  • 4. Polyphyllin I Promoted Melanoma Cells Autophagy and Apoptosis via PI3K/Akt/mTOR Signaling Pathway.
    Long J, Pi X.
    Biomed Res Int; 2020 Jan 01; 2020():5149417. PubMed ID: 32733943
    [Abstract] [Full Text] [Related]

  • 5. Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling.
    Wang K, Huang W, Sang X, Wu X, Shan Q, Tang D, Xu X, Cao G.
    Phytomedicine; 2020 Mar 01; 68():153191. PubMed ID: 32135457
    [Abstract] [Full Text] [Related]

  • 6. A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway.
    Zhang X, Liu Z, Chen S, Li H, Dong L, Fu X.
    J Ethnopharmacol; 2022 Jan 30; 283():114742. PubMed ID: 34655668
    [Abstract] [Full Text] [Related]

  • 7. Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
    Liu Y, Bi T, Wang Z, Wu G, Qian L, Gao Q, Shen G.
    Apoptosis; 2016 Dec 30; 21(12):1398-1407. PubMed ID: 27671687
    [Abstract] [Full Text] [Related]

  • 8. Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway.
    Sun H, Yin M, Qian W, Yin H.
    Med Sci Monit; 2018 Sep 05; 24():6178-6186. PubMed ID: 30182951
    [Abstract] [Full Text] [Related]

  • 9. Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-β/PI3K-AKT-mTOR signaling pathway.
    Wu XL, Wang LK, Yang DD, Qu M, Yang YJ, Guo F, Han L, Xue J.
    J Cell Biochem; 2018 Feb 05; 119(2):2356-2367. PubMed ID: 28884839
    [Abstract] [Full Text] [Related]

  • 10. [Study of isobutyrylshikonin inhibiting proliferation of colon carcinoma cells through PI3K/Akt/m-TOR pathway].
    Zhong Y, Zheng XB, Cai KR, Huang QL, Ye H, Huang Z, Wang YC, Zhu YZ.
    Zhongguo Zhong Yao Za Zhi; 2018 Jun 05; 43(11):2358-2364. PubMed ID: 29945391
    [Abstract] [Full Text] [Related]

  • 11. Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway.
    Li Y, Peng F, Tan X, Wang J, Xu Y.
    Genes Genomics; 2021 Oct 05; 43(10):1189-1198. PubMed ID: 34417976
    [Abstract] [Full Text] [Related]

  • 12. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J, Jiang YY, Chen H, Wu YC, Zhang L.
    Cell Prolif; 2020 Feb 05; 53(2):e12739. PubMed ID: 31820522
    [Abstract] [Full Text] [Related]

  • 13. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
    Martinelli E, Troiani T, D'Aiuto E, Morgillo F, Vitagliano D, Capasso A, Costantino S, Ciuffreda LP, Merolla F, Vecchione L, De Vriendt V, Tejpar S, Nappi A, Sforza V, Martini G, Berrino L, De Palma R, Ciardiello F.
    Int J Cancer; 2013 Nov 05; 133(9):2089-101. PubMed ID: 23629727
    [Abstract] [Full Text] [Related]

  • 14. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer.
    Kumar S, Agnihotri N.
    Biomed Pharmacother; 2019 Jan 05; 109():1462-1477. PubMed ID: 30551398
    [Abstract] [Full Text] [Related]

  • 15. NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Yu Z, Xie G, Zhou G, Cheng Y, Zhang G, Yao G, Chen Y, Li Y, Zhao G.
    Cancer Lett; 2015 Oct 10; 367(1):58-68. PubMed ID: 26188279
    [Abstract] [Full Text] [Related]

  • 16. Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway.
    Zhang H, Jiang H, Zhang H, Liu J, Hu X, Chen L.
    Eur J Pharmacol; 2019 Sep 05; 858():172477. PubMed ID: 31228450
    [Abstract] [Full Text] [Related]

  • 17. Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway.
    Chen S, Yao L.
    Cancer Chemother Pharmacol; 2021 Aug 05; 88(2):323-334. PubMed ID: 33978839
    [Abstract] [Full Text] [Related]

  • 18. IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways.
    Duan S, Huang W, Liu X, Liu X, Chen N, Xu Q, Hu Y, Song W, Zhou J.
    J Exp Clin Cancer Res; 2018 Dec 05; 37(1):304. PubMed ID: 30518405
    [Abstract] [Full Text] [Related]

  • 19. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Dec 05; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 20. Shikonin inhibits proliferation, migration, invasion and promotes apoptosis in NCI-N87 cells via inhibition of PI3K/AKT signal pathway.
    Jia L, Zhu Z, Li H, Li Y.
    Artif Cells Nanomed Biotechnol; 2019 Dec 05; 47(1):2662-2669. PubMed ID: 31257936
    [Abstract] [Full Text] [Related]

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