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Journal Abstract Search

309 related items for PubMed ID: 31243102

  • 1. Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells.
    Shum M, Houde VP, Bellemare V, Junges Moreira R, Bellmann K, St-Pierre P, Viollet B, Foretz M, Marette A.
    J Biol Chem; 2019 Aug 09; 294(32):12250-12260. PubMed ID: 31243102
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.
    Shum M, Bellmann K, St-Pierre P, Marette A.
    Diabetologia; 2016 Mar 09; 59(3):592-603. PubMed ID: 26733005
    [Abstract] [Full Text] [Related]

  • 3. Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
    Pearce LR, Alton GR, Richter DT, Kath JC, Lingardo L, Chapman J, Hwang C, Alessi DR.
    Biochem J; 2010 Oct 15; 431(2):245-55. PubMed ID: 20704563
    [Abstract] [Full Text] [Related]

  • 4. The role of AMPK/mTOR/S6K1 signaling axis in mediating the physiological process of exercise-induced insulin sensitization in skeletal muscle of C57BL/6 mice.
    Liu X, Yuan H, Niu Y, Niu W, Fu L.
    Biochim Biophys Acta; 2012 Nov 15; 1822(11):1716-26. PubMed ID: 22846606
    [Abstract] [Full Text] [Related]

  • 5. AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.
    Tandelilin AA, Hirase T, Hudoyo AW, Cheng J, Toyama K, Morisaki H, Morisaki T.
    BMC Endocr Disord; 2015 Mar 27; 15():11. PubMed ID: 25887856
    [Abstract] [Full Text] [Related]

  • 6. PF-4708671 activates AMPK independently of p70S6K1 inhibition.
    Vainer GW, Saada A, Kania-Almog J, Amartely A, Bar-Tana J, Hertz R.
    PLoS One; 2014 Mar 27; 9(9):e107364. PubMed ID: 25202971
    [Abstract] [Full Text] [Related]

  • 7. Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway.
    Bae EJ, Yang YM, Kim JW, Kim SG.
    Hepatology; 2007 Sep 27; 46(3):730-9. PubMed ID: 17668885
    [Abstract] [Full Text] [Related]

  • 8. Phosphorylation of IRS1 at serine 307 in response to insulin in human adipocytes is not likely to be catalyzed by p70 ribosomal S6 kinase.
    Rajan MR, Fagerholm S, Jönsson C, Kjølhede P, Turkina MV, Strålfors P.
    PLoS One; 2013 Sep 27; 8(4):e59725. PubMed ID: 23565163
    [Abstract] [Full Text] [Related]

  • 9. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
    Veilleux A, Houde VP, Bellmann K, Marette A.
    Mol Endocrinol; 2010 Apr 27; 24(4):766-78. PubMed ID: 20203102
    [Abstract] [Full Text] [Related]

  • 10. Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase.
    Hutchinson DS, Csikasz RI, Yamamoto DL, Shabalina IG, Wikström P, Wilcke M, Bengtsson T.
    Cell Signal; 2007 Jul 27; 19(7):1610-20. PubMed ID: 17391917
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
    Ginion A, Auquier J, Benton CR, Mouton C, Vanoverschelde JL, Hue L, Horman S, Beauloye C, Bertrand L.
    Am J Physiol Heart Circ Physiol; 2011 Aug 27; 301(2):H469-77. PubMed ID: 21602475
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of mitochondrial complex I improves glucose metabolism independently of AMPK activation.
    Hou WL, Yin J, Alimujiang M, Yu XY, Ai LG, Bao YQ, Liu F, Jia WP.
    J Cell Mol Med; 2018 Feb 27; 22(2):1316-1328. PubMed ID: 29106036
    [Abstract] [Full Text] [Related]

  • 13. Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice.
    Xiao F, Yu J, Guo Y, Deng J, Li K, Du Y, Chen S, Zhu J, Sheng H, Guo F.
    Metabolism; 2014 Jun 27; 63(6):841-50. PubMed ID: 24684822
    [Abstract] [Full Text] [Related]

  • 14. Role of AMP-activated protein kinase activators in antiproliferative multi-drug pituitary tumour therapies: effects of combined treatments with compounds affecting the mTOR-p70S6 kinase axis in cultured pituitary tumour cells.
    Tulipano G, Faggi L, Cacciamali A, Spinello M, Cocchi D, Giustina A.
    J Neuroendocrinol; 2015 Jan 27; 27(1):20-32. PubMed ID: 25323047
    [Abstract] [Full Text] [Related]

  • 15. PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1.
    Park JS, Kang DH, Lee DH, Bae SH.
    Biochem Biophys Res Commun; 2015 Oct 23; 466(3):499-504. PubMed ID: 26381178
    [Abstract] [Full Text] [Related]

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  • 17. Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones.
    Hwahng SH, Ki SH, Bae EJ, Kim HE, Kim SG.
    Hepatology; 2009 Jun 23; 49(6):1913-25. PubMed ID: 19378344
    [Abstract] [Full Text] [Related]

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  • 19. Genistein promotes insulin action through adenosine monophosphate-activated protein kinase activation and p70 ribosomal protein S6 kinase 1 inhibition in the skeletal muscle of mice fed a high energy diet.
    Arunkumar E, Anuradha CV.
    Nutr Res; 2012 Aug 23; 32(8):617-25. PubMed ID: 22935345
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