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118 related items for PubMed ID: 31253392

  • 1. ATP11C T418N, a gene mutation causing congenital hemolytic anemia, reduces flippase activity due to improper membrane trafficking.
    Arashiki N, Niitsuma K, Seki M, Takakuwa Y, Nakamura F.
    Biochem Biophys Res Commun; 2019 Aug 27; 516(3):705-712. PubMed ID: 31253392
    [Abstract] [Full Text] [Related]

  • 2. ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia.
    Arashiki N, Takakuwa Y, Mohandas N, Hale J, Yoshida K, Ogura H, Utsugisawa T, Ohga S, Miyano S, Ogawa S, Kojima S, Kanno H.
    Haematologica; 2016 May 27; 101(5):559-65. PubMed ID: 26944472
    [Abstract] [Full Text] [Related]

  • 3. A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia.
    van Dijk MJ, van Oirschot BA, Harrison AN, Recktenwald SM, Qiao M, Stommen A, Cloos AS, Vanderroost J, Terrasi R, Dey K, Bos J, Rab MAE, Bogdanova A, Minetti G, Muccioli GG, Tyteca D, Egée S, Kaestner L, Molday RS, van Beers EJ, van Wijk R.
    Am J Hematol; 2023 Dec 27; 98(12):1877-1887. PubMed ID: 37671681
    [Abstract] [Full Text] [Related]

  • 4. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells.
    Liou AY, Molday LL, Wang J, Andersen JP, Molday RS.
    J Biol Chem; 2019 Apr 26; 294(17):6809-6821. PubMed ID: 30850395
    [Abstract] [Full Text] [Related]

  • 5. Mice deficient in the putative phospholipid flippase ATP11C exhibit altered erythrocyte shape, anemia, and reduced erythrocyte life span.
    Yabas M, Coupland LA, Cromer D, Winterberg M, Teoh NC, D'Rozario J, Kirk K, Bröer S, Parish CR, Enders A.
    J Biol Chem; 2014 Jul 11; 289(28):19531-7. PubMed ID: 24898253
    [Abstract] [Full Text] [Related]

  • 6. Reduction in flippase activity contributes to surface presentation of phosphatidylserine in human senescent erythrocytes.
    Seki M, Arashiki N, Takakuwa Y, Nitta K, Nakamura F.
    J Cell Mol Med; 2020 Dec 11; 24(23):13991-14000. PubMed ID: 33103382
    [Abstract] [Full Text] [Related]

  • 7. Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure.
    Segawa K, Kurata S, Yanagihashi Y, Brummelkamp TR, Matsuda F, Nagata S.
    Science; 2014 Jun 06; 344(6188):1164-8. PubMed ID: 24904167
    [Abstract] [Full Text] [Related]

  • 8. The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane.
    Segawa K, Kurata S, Nagata S.
    J Biol Chem; 2018 Feb 09; 293(6):2172-2182. PubMed ID: 29276178
    [Abstract] [Full Text] [Related]

  • 9. ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.
    Takada N, Takatsu H, Miyano R, Nakayama K, Shin HW.
    J Lipid Res; 2015 Nov 09; 56(11):2151-7. PubMed ID: 26420878
    [Abstract] [Full Text] [Related]

  • 10. Maintenance and regulation of asymmetric phospholipid distribution in human erythrocyte membranes: implications for erythrocyte functions.
    Arashiki N, Takakuwa Y.
    Curr Opin Hematol; 2017 May 09; 24(3):167-172. PubMed ID: 28118222
    [Abstract] [Full Text] [Related]

  • 11. An Unrecognized Function of Cholesterol: Regulating the Mechanism Controlling Membrane Phospholipid Asymmetry.
    Arashiki N, Saito M, Koshino I, Kamata K, Hale J, Mohandas N, Manno S, Takakuwa Y.
    Biochemistry; 2016 Jun 28; 55(25):3504-3513. PubMed ID: 27267274
    [Abstract] [Full Text] [Related]

  • 12. Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane.
    Takatsu H, Tanaka G, Segawa K, Suzuki J, Nagata S, Nakayama K, Shin HW.
    J Biol Chem; 2014 Nov 28; 289(48):33543-56. PubMed ID: 25315773
    [Abstract] [Full Text] [Related]

  • 13. Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation.
    Takatsu H, Takayama M, Naito T, Takada N, Tsumagari K, Ishihama Y, Nakayama K, Shin HW.
    Nat Commun; 2017 Nov 10; 8(1):1423. PubMed ID: 29123098
    [Abstract] [Full Text] [Related]

  • 14. Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.
    Naito T, Takatsu H, Miyano R, Takada N, Nakayama K, Shin HW.
    J Biol Chem; 2015 Jun 12; 290(24):15004-17. PubMed ID: 25947375
    [Abstract] [Full Text] [Related]

  • 15. ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity.
    Paulusma CC, Folmer DE, Ho-Mok KS, de Waart DR, Hilarius PM, Verhoeven AJ, Oude Elferink RP.
    Hepatology; 2008 Jan 12; 47(1):268-78. PubMed ID: 17948906
    [Abstract] [Full Text] [Related]

  • 16. Expression of three P4-phospholipid flippases-atp11a, atp11b, and atp11c in zebrafish (Danio rerio).
    Hawkey-Noble A, Umali J, Fowler G, French CR.
    Gene Expr Patterns; 2020 Jun 12; 36():119115. PubMed ID: 32344036
    [Abstract] [Full Text] [Related]

  • 17. The ratio of ATP11C/PLSCR1 mRNA transcripts has clinical significance in sickle cell anemia.
    Pereira-Martins DA, Coelho-Silva JL, Domingos IF, Weinhäuser I, Franca-Neto PL, Araujo AS, Franca RF, Bezerra MA, Lucena-Araujo AR.
    Ann Hematol; 2022 Feb 12; 101(2):281-287. PubMed ID: 34651249
    [Abstract] [Full Text] [Related]

  • 18. ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes.
    Yabas M, Jing W, Shafik S, Bröer S, Enders A.
    PLoS One; 2016 Feb 12; 11(1):e0146774. PubMed ID: 26799398
    [Abstract] [Full Text] [Related]

  • 19. Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.
    Nakanishi H, Nishizawa T, Segawa K, Nureki O, Fujiyoshi Y, Nagata S, Abe K.
    Cell Rep; 2020 Sep 29; 32(13):108208. PubMed ID: 32997992
    [Abstract] [Full Text] [Related]

  • 20. Crystal structure of a human plasma membrane phospholipid flippase.
    Nakanishi H, Irie K, Segawa K, Hasegawa K, Fujiyoshi Y, Nagata S, Abe K.
    J Biol Chem; 2020 Jul 24; 295(30):10180-10194. PubMed ID: 32493773
    [Abstract] [Full Text] [Related]

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