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Journal Abstract Search

218 related items for PubMed ID: 31254919

  • 1. A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV.
    Wang LL, Battini N, Bheemanaboina RRY, Ansari MF, Chen JP, Xie YP, Cai GX, Zhang SL, Zhou CH.
    Eur J Med Chem; 2019 Oct 01; 179():166-181. PubMed ID: 31254919
    [Abstract] [Full Text] [Related]

  • 2. Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus aureus activity.
    Chen JP, Battini N, Ansari MF, Zhou CH.
    Eur J Med Chem; 2021 May 05; 217():113340. PubMed ID: 33725630
    [Abstract] [Full Text] [Related]

  • 3. Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells.
    Cheng Y, Avula SR, Gao WW, Addla D, Tangadanchu VKR, Zhang L, Lin JM, Zhou CH.
    Eur J Med Chem; 2016 Nov 29; 124():935-945. PubMed ID: 27769037
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.
    Fedorowicz J, Sączewski J, Konopacka A, Waleron K, Lejnowski D, Ciura K, Tomašič T, Skok Ž, Savijoki K, Morawska M, Gilbert-Girard S, Fallarero A.
    Eur J Med Chem; 2019 Oct 01; 179():576-590. PubMed ID: 31279292
    [Abstract] [Full Text] [Related]

  • 5. Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation.
    Liu HB, Gao WW, Tangadanchu VKR, Zhou CH, Geng RX.
    Eur J Med Chem; 2018 Jan 01; 143():66-84. PubMed ID: 29172083
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly global resistance.
    Zang ZL, Wang YX, Battini N, Gao WW, Zhou CH.
    Eur J Med Chem; 2024 Sep 05; 275():116626. PubMed ID: 38944934
    [Abstract] [Full Text] [Related]

  • 7. Action mechanism of 6, 6'-dihydroxythiobinupharidine from Nuphar japonicum, which showed anti-MRSA and anti-VRE activities.
    Okamura S, Nishiyama E, Yamazaki T, Otsuka N, Taniguchi S, Ogawa W, Hatano T, Tsuchiya T, Kuroda T.
    Biochim Biophys Acta; 2015 Jun 05; 1850(6):1245-52. PubMed ID: 25731981
    [Abstract] [Full Text] [Related]

  • 8. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification.
    Xue W, Li X, Ma G, Zhang H, Chen Y, Kirchmair J, Xia J, Wu S.
    Eur J Med Chem; 2020 Feb 15; 188():112022. PubMed ID: 31901744
    [Abstract] [Full Text] [Related]

  • 9. Novel hybrids of metronidazole and quinolones: synthesis, bioactive evaluation, cytotoxicity, preliminary antimicrobial mechanism and effect of metal ions on their transportation by human serum albumin.
    Cui SF, Peng LP, Zhang HZ, Rasheed S, Vijaya Kumar K, Zhou CH.
    Eur J Med Chem; 2014 Oct 30; 86():318-34. PubMed ID: 25173851
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, antibacterial evaluation and docking study of novel 2-hydroxy-3-(nitroimidazolyl)-propyl-derived quinolone.
    Li Q, Xing J, Cheng H, Wang H, Wang J, Wang S, Zhou J, Zhang H.
    Chem Biol Drug Des; 2015 Jan 30; 85(1):79-90. PubMed ID: 25048811
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and structure-activity relationships of novel macrolones: Hybrids of 2-fluoro 9-oxime ketolides and carbamoyl quinolones with highly improved activity against resistant pathogens.
    Ma CX, Lv W, Li YX, Fan BZ, Han X, Kong FS, Tian JC, Cushman M, Liang JH.
    Eur J Med Chem; 2019 May 01; 169():1-20. PubMed ID: 30852383
    [Abstract] [Full Text] [Related]

  • 12. Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism.
    Cui SF, Addla D, Zhou CH.
    J Med Chem; 2016 May 26; 59(10):4488-510. PubMed ID: 27115717
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, Antimicrobial Evaluation, and Interaction of Emodin Alkyl Azoles with DNA and HSA.
    Zhou YH, Wang Y, Zhang HZ.
    Med Chem; 2024 May 26; 20(4):422-433. PubMed ID: 38351695
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains.
    Akunuri R, Veerareddy V, Kaul G, Akhir A, Unnissa T, Parupalli R, Madhavi YV, Chopra S, Nanduri S.
    Bioorg Chem; 2021 Nov 26; 116():105288. PubMed ID: 34454299
    [Abstract] [Full Text] [Related]

  • 15. Dual targeting of DNA gyrase and topoisomerase IV: target interactions of heteroaryl isothiazolones in Staphylococcus aureus.
    Cheng J, Thanassi JA, Thoma CL, Bradbury BJ, Deshpande M, Pucci MJ.
    Antimicrob Agents Chemother; 2007 Jul 26; 51(7):2445-53. PubMed ID: 17502409
    [Abstract] [Full Text] [Related]

  • 16. The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: Modifications at C-12.
    Liu ML, Pan XY, Yang T, Zhang WM, Wang TQ, Wang HY, Lin HX, Yang CG, Cui YM.
    Bioorg Med Chem Lett; 2016 Nov 15; 26(22):5492-5496. PubMed ID: 27777007
    [Abstract] [Full Text] [Related]

  • 17. Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).
    Kim HY, Wiles JA, Wang Q, Pais GC, Lucien E, Hashimoto A, Nelson DM, Thanassi JA, Podos SD, Deshpande M, Pucci MJ, Bradbury BJ.
    J Med Chem; 2011 May 12; 54(9):3268-82. PubMed ID: 21425851
    [Abstract] [Full Text] [Related]

  • 18. Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.
    Zhang L, Addla D, Ponmani J, Wang A, Xie D, Wang YN, Zhang SL, Geng RX, Cai GX, Li S, Zhou CH.
    Eur J Med Chem; 2016 Mar 23; 111():160-82. PubMed ID: 26871658
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects.
    Ibrahim NM, Fahim SH, Hassan M, Farag AE, Georgey HH.
    Eur J Med Chem; 2022 Jan 15; 228():114021. PubMed ID: 34871841
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: length optimization and zero carbon linker oximes.
    Tang D, Gai Y, Polemeropoulos A, Chen Z, Wang Z, Or YS.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):5078-82. PubMed ID: 18762418
    [Abstract] [Full Text] [Related]

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