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273 related items for PubMed ID: 31266804

  • 1. Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.
    Talbot BE, Vandorpe DH, Stotter BR, Alper SL, Schlondorff JS.
    J Biol Chem; 2019 Aug 23; 294(34):12655-12669. PubMed ID: 31266804
    [Abstract] [Full Text] [Related]

  • 2. TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.
    Schlöndorff J, Del Camino D, Carrasquillo R, Lacey V, Pollak MR.
    Am J Physiol Cell Physiol; 2009 Mar 23; 296(3):C558-69. PubMed ID: 19129465
    [Abstract] [Full Text] [Related]

  • 3. Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).
    Chiluiza D, Krishna S, Schumacher VA, Schlöndorff J.
    J Biol Chem; 2013 Jun 21; 288(25):18407-20. PubMed ID: 23645677
    [Abstract] [Full Text] [Related]

  • 4. Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes.
    Polat OK, Uno M, Maruyama T, Tran HN, Imamura K, Wong CF, Sakaguchi R, Ariyoshi M, Itsuki K, Ichikawa J, Morii T, Shirakawa M, Inoue R, Asanuma K, Reiser J, Tochio H, Mori Y, Mori MX.
    J Am Soc Nephrol; 2019 Sep 21; 30(9):1587-1603. PubMed ID: 31266820
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological inhibition of focal segmental glomerulosclerosis-related, gain of function mutants of TRPC6 channels by semi-synthetic derivatives of larixol.
    Urban N, Neuser S, Hentschel A, Köhling S, Rademann J, Schaefer M.
    Br J Pharmacol; 2017 Nov 21; 174(22):4099-4122. PubMed ID: 28800680
    [Abstract] [Full Text] [Related]

  • 6. Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.
    Kanda S, Harita Y, Shibagaki Y, Sekine T, Igarashi T, Inoue T, Hattori S.
    Mol Biol Cell; 2011 Jun 01; 22(11):1824-35. PubMed ID: 21471003
    [Abstract] [Full Text] [Related]

  • 7. Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling.
    Yu J, Zhu C, Yin J, Yu D, Wan F, Tang X, Jiang X.
    Drug Des Devel Ther; 2020 Jun 01; 14():361-370. PubMed ID: 32095070
    [Abstract] [Full Text] [Related]

  • 8. Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes.
    Kim EY, Alvarez-Baron CP, Dryer SE.
    Mol Pharmacol; 2009 Mar 01; 75(3):466-77. PubMed ID: 19052171
    [Abstract] [Full Text] [Related]

  • 9. A novel gain-of-function mutation in transient receptor potential C6 that causes podocytes injury.
    Yu M, Hu J, Ju T, Wang R, Wang M, Gao C, Xia Z.
    Cell Mol Biol (Noisy-le-grand); 2024 May 27; 70(5):284-288. PubMed ID: 38814201
    [Abstract] [Full Text] [Related]

  • 10. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.
    Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schlöndorff J.
    BMC Cell Biol; 2012 Nov 21; 13():33. PubMed ID: 23171048
    [Abstract] [Full Text] [Related]

  • 11. Novel gain-of-function mutation of TRPC6 Q134P contributes to late onset focal segmental glomerulosclerosis in a Chinese pedigree.
    Liu Z, Zhang H, Zhao S, Zhang Q, Zhang R, Han Y, Shao L, Zhao X.
    Nephrology (Carlton); 2021 Dec 21; 26(12):1018-1025. PubMed ID: 34387384
    [Abstract] [Full Text] [Related]

  • 12. N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.
    Dietrich A, Mederos y Schnitzler M, Emmel J, Kalwa H, Hofmann T, Gudermann T.
    J Biol Chem; 2003 Nov 28; 278(48):47842-52. PubMed ID: 12970363
    [Abstract] [Full Text] [Related]

  • 13. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.
    Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J.
    J Biol Chem; 2013 Dec 20; 288(51):36598-609. PubMed ID: 24194522
    [Abstract] [Full Text] [Related]

  • 14. Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes.
    Chen S, He FF, Wang H, Fang Z, Shao N, Tian XJ, Liu JS, Zhu ZH, Wang YM, Wang S, Huang K, Zhang C.
    Cell Calcium; 2011 Dec 20; 50(6):523-9. PubMed ID: 21959089
    [Abstract] [Full Text] [Related]

  • 15. Transient Receptor Potential Canonical 6 (TRPC6) Channel in the Pathogenesis of Diseases: A Jack of Many Trades.
    Saqib U, Munjuluri S, Sarkar S, Biswas S, Mukherjee O, Satsangi H, Baig MS, Obukhov AG, Hajela K.
    Inflammation; 2023 Aug 20; 46(4):1144-1160. PubMed ID: 37072606
    [Abstract] [Full Text] [Related]

  • 16. Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
    Nijenhuis T, Sloan AJ, Hoenderop JG, Flesche J, van Goor H, Kistler AD, Bakker M, Bindels RJ, de Boer RA, Möller CC, Hamming I, Navis G, Wetzels JF, Berden JH, Reiser J, Faul C, van der Vlag J.
    Am J Pathol; 2011 Oct 20; 179(4):1719-32. PubMed ID: 21839714
    [Abstract] [Full Text] [Related]

  • 17. Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6).
    Azumaya CM, Sierra-Valdez F, Cordero-Morales JF, Nakagawa T.
    J Biol Chem; 2018 Jun 29; 293(26):10381-10391. PubMed ID: 29752403
    [Abstract] [Full Text] [Related]

  • 18. Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol.
    Anderson M, Kim EY, Hagmann H, Benzing T, Dryer SE.
    Am J Physiol Cell Physiol; 2013 Aug 01; 305(3):C276-89. PubMed ID: 23657570
    [Abstract] [Full Text] [Related]

  • 19. An inactivating human TRPC6 channel mutation without focal segmental glomerulosclerosis.
    Batool L, Hariharan K, Xu Y, Kaßmann M, Tsvetkov D, Gohlke BO, Kaden S, Gossen M, Nürnberg B, Kurtz A, Gollasch M.
    Cell Mol Life Sci; 2023 Aug 24; 80(9):265. PubMed ID: 37615749
    [Abstract] [Full Text] [Related]

  • 20. Calcium-Sensing Receptor Stimulation in Cultured Glomerular Podocytes Induces TRPC6-Dependent Calcium Entry and RhoA Activation.
    Zhang L, Ji T, Wang Q, Meng K, Zhang R, Yang H, Liao C, Ma L, Jiao J.
    Cell Physiol Biochem; 2017 Aug 24; 43(5):1777-1789. PubMed ID: 29050010
    [Abstract] [Full Text] [Related]

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