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488 related items for PubMed ID: 31279292
21. Structure based design and synthesis of 3-(7-nitro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanehydrazide derivatives as novel bacterial DNA-gyrase inhibitors: In-vitro, In-vivo, In-silico and SAR studies. Saleh MA, Elmaaty AA, El Saeed HS, Saleh MM, Salah M, Ezz Eldin RR. Bioorg Chem; 2022 Dec; 129():106186. PubMed ID: 36215786 [Abstract] [Full Text] [Related]
22. Synthesis and antibacterial activity of quinolone-based compounds containing a coumarin moiety. Emami S, Foroumadi A, Faramarzi MA, Samadi N. Arch Pharm (Weinheim); 2008 Jan; 341(1):42-8. PubMed ID: 18072241 [Abstract] [Full Text] [Related]
23. New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV. Badshah SL, Ullah A. Eur J Med Chem; 2018 May 25; 152():393-400. PubMed ID: 29751233 [Abstract] [Full Text] [Related]
24. Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors. Jakopin Ž, Ilaš J, Barančoková M, Brvar M, Tammela P, Sollner Dolenc M, Tomašič T, Kikelj D. Eur J Med Chem; 2017 Apr 21; 130():171-184. PubMed ID: 28246042 [Abstract] [Full Text] [Related]
25. Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin. Kocsis B, Domokos J, Szabo D. Ann Clin Microbiol Antimicrob; 2016 May 23; 15(1):34. PubMed ID: 27215369 [Abstract] [Full Text] [Related]
26. Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies. Ammar YA, Farag AA, Ali AM, Hessein SA, Askar AA, Fayed EA, Elsisi DM, Ragab A. Bioorg Chem; 2020 Jun 23; 99():103841. PubMed ID: 32325335 [Abstract] [Full Text] [Related]
27. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents. Alagumuthu M, Arumugam S. Bioorg Med Chem; 2017 Feb 15; 25(4):1448-1455. PubMed ID: 28094220 [Abstract] [Full Text] [Related]
28. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity. Omar MA, Masaret GS, Abbas EMH, Abdel-Aziz MM, Harras MF, Farghaly TA. Bioorg Chem; 2020 Nov 15; 104():104316. PubMed ID: 33022549 [Abstract] [Full Text] [Related]
29. Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities. Aziz HA, El-Saghier AMM, Badr M, Abuo-Rahma GEA, Shoman ME. Mol Divers; 2022 Jun 15; 26(3):1743-1759. PubMed ID: 34455532 [Abstract] [Full Text] [Related]
30. Synthesis, Antimicrobial Evaluation and Molecular Docking of Some Potential 2,6-disubstituted 1H-Benzimidazoles; Non-Classical Antifolates. Harer S, Bhatia M, Kawade V. Med Chem; 2019 Jun 15; 15(7):813-832. PubMed ID: 30727904 [Abstract] [Full Text] [Related]
31. 3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms. Ellsworth EL, Tran TP, Showalter HD, Sanchez JP, Watson BM, Stier MA, Domagala JM, Gracheck SJ, Joannides ET, Shapiro MA, Dunham SA, Hanna DL, Huband MD, Gage JW, Bronstein JC, Liu JY, Nguyen DQ, Singh R. J Med Chem; 2006 Nov 02; 49(22):6435-8. PubMed ID: 17064062 [Abstract] [Full Text] [Related]
32. New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens. Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašič LP, Tomašič T. Eur J Med Chem; 2021 Mar 05; 213():113200. PubMed ID: 33524686 [Abstract] [Full Text] [Related]
33. Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens. Hu XE, Kim NK, Gray JL, Almstead JI, Seibel WL, Ledoussal B. J Med Chem; 2003 Aug 14; 46(17):3655-61. PubMed ID: 12904069 [Abstract] [Full Text] [Related]
34. Covalently linked kanamycin - Ciprofloxacin hybrid antibiotics as a tool to fight bacterial resistance. Shavit M, Pokrovskaya V, Belakhov V, Baasov T. Bioorg Med Chem; 2017 Jun 01; 25(11):2917-2925. PubMed ID: 28343755 [Abstract] [Full Text] [Related]
35. Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae. Okumura R, Hirata T, Onodera Y, Hoshino K, Otani T, Yamamoto T. J Antimicrob Chemother; 2008 Jul 01; 62(1):98-104. PubMed ID: 18390884 [Abstract] [Full Text] [Related]
36. Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents. Zhang L, Addla D, Ponmani J, Wang A, Xie D, Wang YN, Zhang SL, Geng RX, Cai GX, Li S, Zhou CH. Eur J Med Chem; 2016 Mar 23; 111():160-82. PubMed ID: 26871658 [Abstract] [Full Text] [Related]
37. Antibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound. Butler MM, Lamarr WA, Foster KA, Barnes MH, Skow DJ, Lyden PT, Kustigian LM, Zhi C, Brown NC, Wright GE, Bowlin TL. Antimicrob Agents Chemother; 2007 Jan 23; 51(1):119-27. PubMed ID: 17074800 [Abstract] [Full Text] [Related]
38. An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors. Tiz DB, Skok Ž, Durcik M, Tomašič T, Mašič LP, Ilaš J, Zega A, Draskovits G, Révész T, Nyerges Á, Pál C, Cruz CD, Tammela P, Žigon D, Kikelj D, Zidar N. Eur J Med Chem; 2019 Apr 01; 167():269-290. PubMed ID: 30776691 [Abstract] [Full Text] [Related]
39. Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents. Wiles JA, Hashimoto A, Thanassi JA, Cheng J, Incarvito CD, Deshpande M, Pucci MJ, Bradbury BJ. J Med Chem; 2006 Jan 12; 49(1):39-42. PubMed ID: 16392790 [Abstract] [Full Text] [Related]
40. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification. Xue W, Li X, Ma G, Zhang H, Chen Y, Kirchmair J, Xia J, Wu S. Eur J Med Chem; 2020 Feb 15; 188():112022. PubMed ID: 31901744 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]