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Journal Abstract Search
158 related items for PubMed ID: 31280668
1. Labelled chemical probes for demonstrating direct target engagement in living systems. Prevet H, Collins I. Future Med Chem; 2019 May; 11(10):1195-1224. PubMed ID: 31280668 [Abstract] [Full Text] [Related]
2. Target Identification Using Chemical Probes. Moustakim M, Felce SL, Zaarour N, Farnie G, McCann FE, Brennan PE. Methods Enzymol; 2018 May; 610():27-58. PubMed ID: 30390803 [Abstract] [Full Text] [Related]
3. Bioorthogonal Probes for the Study of MDM2-p53 Inhibitors in Cells and Development of High-Content Screening Assays for Drug Discovery. D'Alessandro PL, Buschmann N, Kaufmann M, Furet P, Baysang F, Brunner R, Marzinzik A, Vorherr T, Stachyra TM, Ottl J, Lizos DE, Cobos-Correa A. Angew Chem Int Ed Engl; 2016 Dec 23; 55(52):16026-16030. PubMed ID: 27874234 [Abstract] [Full Text] [Related]
4. Quantifying drug-target engagement in live cells using sulfonyl fluoride chemical probes. Jones LH, Xu H, Fadeyi OO. Methods Enzymol; 2019 Dec 23; 622():201-220. PubMed ID: 31155053 [Abstract] [Full Text] [Related]
5. Construction of Protein-Based Biosensors Using Ligand-Directed Chemistry for Detecting Analyte Binding. Yamaura K, Kiyonaka S, Hamachi I. Methods Enzymol; 2017 Dec 23; 589():253-280. PubMed ID: 28336066 [Abstract] [Full Text] [Related]
6. Cu2+ Biological Imaging Probes Based on Different Sensing Mechanisms. Yin C, Li J, Huo F. Curr Med Chem; 2019 Dec 23; 26(21):3958-4002. PubMed ID: 28462709 [Abstract] [Full Text] [Related]
7. Molecular Design of Bioorthogonal Probes and Imaging Reagents Derived from Photofunctional Transition Metal Complexes. Lo KK. Acc Chem Res; 2020 Jan 21; 53(1):32-44. PubMed ID: 31916746 [Abstract] [Full Text] [Related]
8. Design and Application of Receptor-Targeted Fluorescent Probes Based on Small Molecular Fluorescent Dyes. Zhang Y, Li S, Zhang H, Xu H. Bioconjug Chem; 2021 Jan 20; 32(1):4-24. PubMed ID: 33412857 [Abstract] [Full Text] [Related]
9. Quantifying Target Occupancy of Small Molecules Within Living Cells. Robers MB, Friedman-Ohana R, Huber KVM, Kilpatrick L, Vasta JD, Berger BT, Chaudhry C, Hill S, Müller S, Knapp S, Wood KV. Annu Rev Biochem; 2020 Jun 20; 89():557-581. PubMed ID: 32208767 [Abstract] [Full Text] [Related]
10. Target engagement in lead generation. Durham TB, Blanco MJ. Bioorg Med Chem Lett; 2015 Mar 01; 25(5):998-1008. PubMed ID: 25630223 [Abstract] [Full Text] [Related]
11. Fluorescent probes for G-protein-coupled receptor drug discovery. Iliopoulos-Tsoutsouvas C, Kulkarni RN, Makriyannis A, Nikas SP. Expert Opin Drug Discov; 2018 Oct 01; 13(10):933-947. PubMed ID: 30249143 [Abstract] [Full Text] [Related]
12. Use of optical imaging to progress novel therapeutics to the clinic. Byrne WL, DeLille A, Kuo C, de Jong JS, van Dam GM, Francis KP, Tangney M. J Control Release; 2013 Dec 10; 172(2):523-34. PubMed ID: 23680286 [Abstract] [Full Text] [Related]
13. Small-molecule fluorophores and fluorescent probes for bioimaging. Terai T, Nagano T. Pflugers Arch; 2013 Mar 10; 465(3):347-59. PubMed ID: 23412659 [Abstract] [Full Text] [Related]
14. Resorufin-based responsive probes for fluorescence and colorimetric analysis. Tian L, Feng H, Dai Z, Zhang R. J Mater Chem B; 2021 Jan 07; 9(1):53-79. PubMed ID: 33226060 [Abstract] [Full Text] [Related]
15. Evaluation of four affibody-based near-infrared fluorescent probes for optical imaging of epidermal growth factor receptor positive tumors. Qi S, Miao Z, Liu H, Xu Y, Feng Y, Cheng Z. Bioconjug Chem; 2012 Jun 20; 23(6):1149-56. PubMed ID: 22621238 [Abstract] [Full Text] [Related]
16. Developments in fluorescent probes for receptor research. Leopoldo M, Lacivita E, Berardi F, Perrone R. Drug Discov Today; 2009 Jul 20; 14(13-14):706-12. PubMed ID: 19573791 [Abstract] [Full Text] [Related]
17. Quantitative imaging of receptor-ligand engagement in intact live animals. Rudkouskaya A, Sinsuebphon N, Ward J, Tubbesing K, Intes X, Barroso M. J Control Release; 2018 Sep 28; 286():451-459. PubMed ID: 30036545 [Abstract] [Full Text] [Related]
18. Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery. Chen Y, Sun D, Yang R, Lim J, Sondey C, Presland J, Rakhilina L, Addona G, Kariv I, Chen H. SLAS Discov; 2021 Sep 28; 26(8):1040-1054. PubMed ID: 34130529 [Abstract] [Full Text] [Related]
19. Single fluorescent probe distinguishes hydrogen peroxide and nitric oxide in cell imaging. Yuan L, Lin W, Zhu S, Zheng K, He L. Methods Enzymol; 2013 Sep 28; 526():83-106. PubMed ID: 23791095 [Abstract] [Full Text] [Related]
20. Fluorescent probes for sensing and imaging biological hydrogen sulfide. Lin VS, Chang CJ. Curr Opin Chem Biol; 2012 Dec 28; 16(5-6):595-601. PubMed ID: 22921406 [Abstract] [Full Text] [Related] Page: [Next] [New Search]