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Journal Abstract Search

184 related items for PubMed ID: 31287605

  • 1.
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  • 2. Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain.
    Henderson BW, Gentry EG, Rush T, Troncoso JC, Thambisetty M, Montine TJ, Herskowitz JH.
    J Neurochem; 2016 Aug; 138(4):525-31. PubMed ID: 27246255
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  • 3. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model.
    Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ.
    J Neurosci; 2013 Dec 04; 33(49):19086-98. PubMed ID: 24305806
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  • 6. The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
    Oishi M, Nairn AC, Czernik AJ, Lim GS, Isohara T, Gandy SE, Greengard P, Suzuki T.
    Mol Med; 1997 Feb 04; 3(2):111-23. PubMed ID: 9085254
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  • 7. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z, Zhang F, Tao L, Zheng W, Cao Y, Wang Z, Tang S, Le K, Chen S, Pi R, Liu P.
    Neurosci Lett; 2009 Mar 13; 452(2):90-5. PubMed ID: 19154776
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  • 8. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun 13; 37(12):1962-9. PubMed ID: 23773065
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  • 10. CART modulates beta-amyloid metabolism-associated enzymes and attenuates memory deficits in APP/PS1 mice.
    Yin K, Jin J, Zhu X, Yu L, Wang S, Qian L, Han L, Xu Y.
    Neurol Res; 2017 Oct 13; 39(10):885-894. PubMed ID: 28743230
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  • 11. Attenuation of amyloid-β generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35.
    Chau DD, Yung KW, Chan WW, An Y, Hao Y, Chan HE, Ngo JC, Lau KF.
    FASEB J; 2019 Nov 13; 33(11):12019-12035. PubMed ID: 31373844
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  • 12. RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity.
    Fang F, Yu Q, Arancio O, Chen D, Gore SS, Yan SS, Yan SF.
    Hum Mol Genet; 2018 Mar 15; 27(6):1002-1014. PubMed ID: 29329433
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  • 13. Multitarget Therapeutic Effect of Fasudil in APP/PS1transgenic Mice.
    Yu JZ, Li YH, Liu CY, Wang Q, Gu QF, Wang HQ, Zhang GX, Xiao BG, Ma CG.
    CNS Neurol Disord Drug Targets; 2017 Mar 15; 16(2):199-209. PubMed ID: 27401064
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  • 14. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
    Song JX, Malampati S, Zeng Y, Durairajan SSK, Yang CB, Tong BC, Iyaswamy A, Shang WB, Sreenivasmurthy SG, Zhu Z, Cheung KH, Lu JH, Tang C, Xu N, Li M.
    Aging Cell; 2020 Feb 15; 19(2):e13069. PubMed ID: 31858697
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  • 15. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
    Tian J, Shi J, Zhang L, Yin J, Hu Q, Xu Y, Sheng S, Wang P, Ren Y, Wang R, Wang Y.
    Curr Alzheimer Res; 2009 Apr 15; 6(2):118-31. PubMed ID: 19355846
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  • 16. Dihydromyricetin inhibits microglial activation and neuroinflammation by suppressing NLRP3 inflammasome activation in APP/PS1 transgenic mice.
    Feng J, Wang JX, Du YH, Liu Y, Zhang W, Chen JF, Liu YJ, Zheng M, Wang KJ, He GQ.
    CNS Neurosci Ther; 2018 Dec 15; 24(12):1207-1218. PubMed ID: 29869390
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  • 17. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice.
    Liu HL, Zhao G, Zhang H, Shi LD.
    Behav Brain Res; 2013 Nov 01; 256():261-72. PubMed ID: 23968591
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  • 18. Bispecific Antibody Fragment Targeting APP and Inducing α-Site Cleavage Restores Neuronal Health in an Alzheimer's Mouse Model.
    He P, Xin W, Schulz P, Sierks MR.
    Mol Neurobiol; 2019 Nov 01; 56(11):7420-7432. PubMed ID: 31041656
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  • 19. Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β.
    Menon PK, Koistinen NA, Iverfeldt K, Ström AL.
    J Biol Chem; 2019 Nov 22; 294(47):17768-17776. PubMed ID: 31604820
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  • 20. APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models.
    Bignante EA, Ponce NE, Heredia F, Musso J, Krawczyk MC, Millán J, Pigino GF, Inestrosa NC, Boccia MM, Lorenzo A.
    Neurobiol Aging; 2018 Apr 22; 64():44-57. PubMed ID: 29331876
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