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200 related items for PubMed ID: 3130679

  • 1. Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat.
    Liu YL, Roebuck BD, Yager JD, Groopman JD, Kensler TW.
    Toxicol Appl Pharmacol; 1988 May; 93(3):442-51. PubMed ID: 3130679
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  • 3. Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.
    Roebuck BD, Liu YL, Rogers AE, Groopman JD, Kensler TW.
    Cancer Res; 1991 Oct 15; 51(20):5501-6. PubMed ID: 1680553
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  • 4. Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione.
    Kensler TW, Egner PA, Trush MA, Bueding E, Groopman JD.
    Carcinogenesis; 1985 May 15; 6(5):759-63. PubMed ID: 3924431
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  • 5. Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
    Maxuitenko YY, MacMillan DL, Kensler TW, Roebuck BD.
    Carcinogenesis; 1993 Nov 15; 14(11):2423-5. PubMed ID: 8242875
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  • 6. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Kensler TW, Groopman JD, Eaton DL, Curphey TJ, Roebuck BD.
    Carcinogenesis; 1992 Jan 15; 13(1):95-100. PubMed ID: 1346373
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  • 7. Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
    Bolton MG, Muñoz A, Jacobson LP, Groopman JD, Maxuitenko YY, Roebuck BD, Kensler TW.
    Cancer Res; 1993 Aug 01; 53(15):3499-504. PubMed ID: 8339253
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  • 8. Inhibition of aflatoxin Ml excretion in rat urine during dietary intervention with oltipraz.
    Scholl P, Musser SM, Kensler TW, Groopman JD.
    Carcinogenesis; 1996 Jun 01; 17(6):1385-8. PubMed ID: 8681461
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  • 9. Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
    Primiano T, Egner PA, Sutter TR, Kelloff GJ, Roebuck BD, Kensler TW.
    Cancer Res; 1995 Oct 01; 55(19):4319-24. PubMed ID: 7671242
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  • 11. Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver.
    Davidson NE, Egner PA, Kensler TW.
    Cancer Res; 1990 Apr 15; 50(8):2251-5. PubMed ID: 2317812
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  • 12. Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats.
    Rao CV, Nayini J, Reddy BS.
    Proc Soc Exp Biol Med; 1991 May 15; 197(1):77-84. PubMed ID: 2020672
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  • 13. Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
    Kensler TW, Egner PA, Davidson NE, Roebuck BD, Pikul A, Groopman JD.
    Cancer Res; 1986 Aug 15; 46(8):3924-31. PubMed ID: 2873884
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  • 14. Identification of dithiolethiones with better chemopreventive properties than oltipraz.
    Maxuitenko YY, Libby AH, Joyner HH, Curphey TJ, MacMillan DL, Kensler TW, Roebuck BD.
    Carcinogenesis; 1998 Sep 15; 19(9):1609-15. PubMed ID: 9771932
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  • 15. Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.
    Kelly VP, Ellis EM, Manson MM, Chanas SA, Moffat GJ, McLeod R, Judah DJ, Neal GE, Hayes JD.
    Cancer Res; 2000 Feb 15; 60(4):957-69. PubMed ID: 10706111
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  • 16. Effect of butylated hydroxyanisole pretreatment on in vitro hepatic aflatoxin B1-DNA binding and aflatoxin B1-glutathione conjugation in rats.
    Jhee EC, Ho LL, Lotlikar PD.
    Cancer Res; 1988 May 15; 48(10):2688-92. PubMed ID: 3129185
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  • 20. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism.
    Manson MM, Ball HW, Barrett MC, Clark HL, Judah DJ, Williamson G, Neal GE.
    Carcinogenesis; 1997 Sep 15; 18(9):1729-38. PubMed ID: 9328168
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