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392 related items for PubMed ID: 31322047

  • 1. Ara-c induces cell cycle G1/S arrest by inducing upregulation of the INK4 family gene or directly inhibiting the formation of the cell cycle-dependent complex CDK4/cyclin D1.
    Sun F, Li N, Tong X, Zeng J, He S, Gai T, Bai Y, Liu L, Lu K, Shen J, Han M, Lu C, Dai F.
    Cell Cycle; 2019 Sep; 18(18):2293-2306. PubMed ID: 31322047
    [Abstract] [Full Text] [Related]

  • 2. Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer cells.
    Kim HS, Lee WJ, Lee SW, Chae HW, Kim DH, Oh Y.
    Horm Metab Res; 2010 Mar; 42(3):165-72. PubMed ID: 19960406
    [Abstract] [Full Text] [Related]

  • 3. RN181 is a tumour suppressor in gastric cancer by regulation of the ERK/MAPK-cyclin D1/CDK4 pathway.
    Wang S, Wang X, Gao Y, Peng Y, Dong N, Xie Q, Zhang X, Wu Y, Li M, Li JL.
    J Pathol; 2019 Jun; 248(2):204-216. PubMed ID: 30714150
    [Abstract] [Full Text] [Related]

  • 4. CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.
    Gogolin S, Ehemann V, Becker G, Brueckner LM, Dreidax D, Bannert S, Nolte I, Savelyeva L, Bell E, Westermann F.
    Cell Cycle; 2013 Apr 01; 12(7):1091-104. PubMed ID: 23462184
    [Abstract] [Full Text] [Related]

  • 5. Simvastatin induces G1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells.
    Chen MJ, Cheng AC, Lee MF, Hsu YC.
    J Cell Physiol; 2018 Jun 01; 233(6):4618-4625. PubMed ID: 28833099
    [Abstract] [Full Text] [Related]

  • 6. Formononetin promotes cell cycle arrest via downregulation of Akt/Cyclin D1/CDK4 in human prostate cancer cells.
    Li T, Zhao X, Mo Z, Huang W, Yan H, Ling Z, Ye Y.
    Cell Physiol Biochem; 2014 Jun 01; 34(4):1351-8. PubMed ID: 25301361
    [Abstract] [Full Text] [Related]

  • 7. 6-Gingerol induces cell-cycle G1-phase arrest through AKT-GSK 3β-cyclin D1 pathway in renal-cell carcinoma.
    Xu S, Zhang H, Liu T, Yang W, Lv W, He D, Guo P, Li L.
    Cancer Chemother Pharmacol; 2020 Feb 01; 85(2):379-390. PubMed ID: 31832810
    [Abstract] [Full Text] [Related]

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  • 9. miR-206 functions as a novel cell cycle regulator and tumor suppressor in clear-cell renal cell carcinoma.
    Xiao H, Xiao W, Cao J, Li H, Guan W, Guo X, Chen K, Zheng T, Ye Z, Wang J, Xu H.
    Cancer Lett; 2016 Apr 28; 374(1):107-116. PubMed ID: 26808577
    [Abstract] [Full Text] [Related]

  • 10. A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.
    Vincent-Fabert C, Fiancette R, Rouaud P, Baudet C, Truffinet V, Magnone V, Guillaudeau A, Cogné M, Dubus P, Denizot Y.
    Am J Pathol; 2012 Apr 28; 180(4):1688-701. PubMed ID: 22326754
    [Abstract] [Full Text] [Related]

  • 11. RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1.
    Chen SH, Gong X, Zhang Y, Van Horn RD, Yin T, Huber L, Burke TF, Manro J, Iversen PW, Wu W, Bhagwat SV, Beckmann RP, Tiu RV, Buchanan SG, Peng SB.
    Oncogene; 2018 Feb 08; 37(6):821-832. PubMed ID: 29059158
    [Abstract] [Full Text] [Related]

  • 12. Bisphenol S promotes the cell cycle progression and cell proliferation through ERα-cyclin D-CDK4/6-pRb pathway in MCF-7 breast cancer cells.
    Lin Z, Zhang X, Zhao F, Ru S.
    Toxicol Appl Pharmacol; 2019 Mar 01; 366():75-82. PubMed ID: 30684532
    [Abstract] [Full Text] [Related]

  • 13. CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells.
    Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, Liu J, Jiang Q, Zhang H, Zhang C.
    J Biol Chem; 2017 Jun 16; 292(24):10131-10141. PubMed ID: 28446612
    [Abstract] [Full Text] [Related]

  • 14. Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression.
    Grillo M, Bott MJ, Khandke N, McGinnis JP, Miranda M, Meyyappan M, Rosfjord EC, Rabindran SK.
    Breast Cancer Res Treat; 2006 Jan 16; 95(2):185-94. PubMed ID: 16319987
    [Abstract] [Full Text] [Related]

  • 15. Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
    Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, Wang Y, Zhou F, Zhou Y.
    Artif Cells Nanomed Biotechnol; 2019 Dec 16; 47(1):4001-4011. PubMed ID: 31588803
    [Abstract] [Full Text] [Related]

  • 16. ClC-3 Chloride Channel Proteins Regulate the Cell Cycle by Up-regulating cyclin D1-CDK4/6 through Suppressing p21/p27 Expression in Nasopharyngeal Carcinoma Cells.
    Ye D, Luo H, Lai Z, Zou L, Zhu L, Mao J, Jacob T, Ye W, Wang L, Chen L.
    Sci Rep; 2016 Jul 25; 6():30276. PubMed ID: 27451945
    [Abstract] [Full Text] [Related]

  • 17. CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest.
    Wang J, Li Q, Yuan J, Wang J, Chen Z, Liu Z, Li Z, Lai Y, Gao J, Shen L.
    J Transl Med; 2017 Jun 02; 15(1):127. PubMed ID: 28578693
    [Abstract] [Full Text] [Related]

  • 18. The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation.
    Yadav V, Burke TF, Huber L, Van Horn RD, Zhang Y, Buchanan SG, Chan EM, Starling JJ, Beckmann RP, Peng SB.
    Mol Cancer Ther; 2014 Oct 02; 13(10):2253-63. PubMed ID: 25122067
    [Abstract] [Full Text] [Related]

  • 19. Attenuation of krüppel-like factor 4 facilitates carcinogenesis by inducing g1/s phase arrest in clear cell renal cell carcinoma.
    Song E, Ma X, Li H, Zhang P, Ni D, Chen W, Gao Y, Fan Y, Pang H, Shi T, Ding Q, Wang B, Zhang Y, Zhang X.
    PLoS One; 2013 Oct 02; 8(7):e67758. PubMed ID: 23861801
    [Abstract] [Full Text] [Related]

  • 20. A3 adenosine receptor agonist induce G1 cell cycle arrest via Cyclin D and cyclin-dependent kinase 4 pathways in OVCAR-3 and Caov-4 cell lines.
    Joshaghani HR, Jafari SM, Aghaei M, Panjehpour M, Abedi H.
    J Cancer Res Ther; 2017 Oct 02; 13(1):107-112. PubMed ID: 28508842
    [Abstract] [Full Text] [Related]

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