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Journal Abstract Search

190 related items for PubMed ID: 31345747

  • 1. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 2. Design and Synthesis of N-Substituted 3,4-Pyrroledicarboximides as Potential Anti-Inflammatory Agents.
    Redzicka A, Czyżnikowska Ż, Wiatrak B, Gębczak K, Kochel A.
    Int J Mol Sci; 2021 Jan 30; 22(3):. PubMed ID: 33573356
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, molecular docking, antimycobacterial and antimicrobial evaluation of new pyrrolo[3,2-c]pyridine Mannich bases.
    Jose G, Suresha Kumara TH, Sowmya HBV, Sriram D, Guru Row TN, Hosamani AA, More SS, Janardhan B, Harish BG, Telkar S, Ravikumar YS.
    Eur J Med Chem; 2017 May 05; 131():275-288. PubMed ID: 28340368
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, anti-inflammatory activity, and molecular docking studies of some novel Mannich bases of the 1,3,4-oxadiazole-2(3H)-thione scaffold.
    Ozyazici T, Gurdal EE, Orak D, Sipahi H, Ercetin T, Gulcan HO, Koksal M.
    Arch Pharm (Weinheim); 2020 Jul 05; 353(7):e2000061. PubMed ID: 32319141
    [Abstract] [Full Text] [Related]

  • 5. Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors.
    Szczukowski Ł, Krzyżak E, Zborowska A, Zając P, Potyrak K, Peregrym K, Wiatrak B, Marciniak A, Świątek P.
    Int J Mol Sci; 2020 Dec 17; 21(24):. PubMed ID: 33348757
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, anti-inflammatory activity and molecular docking of potential novel antipyrine and pyrazolone analogs as cyclooxygenase enzyme (COX) inhibitors.
    El Sayed MT, El-Sharief MAMS, Zarie ES, Morsy NM, Elsheakh AR, Voronkov A, Berishvili V, Hassan GS.
    Bioorg Med Chem Lett; 2018 Mar 01; 28(5):952-957. PubMed ID: 29426771
    [Abstract] [Full Text] [Related]

  • 7. Design, Synthesis, Biological Evaluation, and Molecular Docking Study of 4,6-Dimethyl-5-aryl/alkyl-2-[2-hydroxy-3-(4-substituted-1-piperazinyl)propyl]pyrrolo[3,4-c]pyrrole-1,3(2H,5H)-diones as Anti-Inflammatory Agents with Dual Inhibition of COX and LOX.
    Redzicka A, Wiatrak B, Jęśkowiak-Kossakowska I, Kochel A, Płaczek R, Czyżnikowska Ż.
    Pharmaceuticals (Basel); 2023 May 29; 16(6):. PubMed ID: 37375750
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation as well as in silico studies of arylpiperazine-1,2-benzothiazine derivatives as novel anti-inflammatory agents.
    Szczęśniak-Sięga BM, Wiatrak B, Czyżnikowska Ż, Janczak J, Wiglusz RJ, Maniewska J.
    Bioorg Chem; 2021 Jan 29; 106():104476. PubMed ID: 33250206
    [Abstract] [Full Text] [Related]

  • 9. In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone as Promising Cyclooxygenase Inhibitors.
    Peregrym K, Szczukowski Ł, Wiatrak B, Potyrak K, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2021 Aug 24; 22(17):. PubMed ID: 34502040
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
    Palkar MB, Singhai AS, Ronad PM, Vishwanathswamy AH, Boreddy TS, Veerapur VP, Shaikh MS, Rane RA, Karpoormath R.
    Bioorg Med Chem; 2014 May 15; 22(10):2855-66. PubMed ID: 24751552
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, characterization, and in vivo pharmacological evaluation of novel mannich bases derived from 1,2,4-triazole containing a naproxen moiety.
    Avci A, Taşci H, Kandemir Ü, Can ÖD, Gökhan-Kelekçi N, Tozkoparan B.
    Bioorg Chem; 2020 Jul 15; 100():103892. PubMed ID: 32388433
    [Abstract] [Full Text] [Related]

  • 12. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 15; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 13. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study.
    Sakr A, Kothayer H, Ibrahim SM, Baraka MM, Rezq S.
    Bioorg Chem; 2019 Mar 15; 84():76-86. PubMed ID: 30481648
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of new 4-phenylpyrimidine-2(1H)-thiones and their potency to inhibit COX-1 and COX-2.
    Seebacher W, Faist J, Presser A, Weis R, Saf R, Kaserer T, Temml V, Schuster D, Ortmann S, Otto N, Bauer R.
    Eur J Med Chem; 2015 Aug 28; 101():552-9. PubMed ID: 26197159
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors.
    Chen Z, Wang ZC, Yan XQ, Wang PF, Lu XY, Chen LW, Zhu HL, Zhang HW.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1947-51. PubMed ID: 25866240
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, biological evaluation and in silico studies of novel pyrrolo[3,4-d]pyridazinone derivatives withpromising anti-inflammatory and antioxidant activity.
    Szczukowski Ł, Redzicka A, Wiatrak B, Krzyżak E, Marciniak A, Gębczak K, Gębarowski T, Świątek P.
    Bioorg Chem; 2020 Sep 01; 102():104035. PubMed ID: 32721780
    [Abstract] [Full Text] [Related]

  • 17. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G, Alaaeddine R, Alaeddine LM, Nassra R, Belal ASF, Ismail A, El-Yazbi AF, Abdel-Ghany YS, Hazzaa A.
    Eur J Med Chem; 2018 Jan 20; 144():635-650. PubMed ID: 29289887
    [Abstract] [Full Text] [Related]

  • 18. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
    Bioorg Chem; 2018 Aug 20; 78():80-93. PubMed ID: 29550533
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA.
    Bioorg Med Chem; 2018 Nov 01; 26(20):5388-5396. PubMed ID: 30293795
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and in-silico studies of some diaryltriazole derivatives as potential cyclooxygenase inhibitors.
    Radwan AA, elTahir KE.
    Arch Pharm Res; 2013 May 01; 36(5):553-63. PubMed ID: 23479193
    [Abstract] [Full Text] [Related]

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