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Journal Abstract Search


203 related items for PubMed ID: 31399644

  • 1. Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch.
    Tashiro E.
    J Antibiot (Tokyo); 2019 Dec; 72(12):899-905. PubMed ID: 31399644
    [Abstract] [Full Text] [Related]

  • 2. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, Hu Y, Fabre C, Minami J, Ohguchi H, Kiziltepe T, Ikeda H, Kawano Y, French M, Blumenthal M, Tam V, Kertesz NL, Malyankar UM, Hokenson M, Pham T, Zeng Q, Patterson JB, Richardson PG, Munshi NC, Anderson KC.
    Blood; 2012 Jun 14; 119(24):5772-81. PubMed ID: 22538852
    [Abstract] [Full Text] [Related]

  • 3. Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.
    Jiang D, Niwa M, Koong AC.
    Semin Cancer Biol; 2015 Aug 14; 33():48-56. PubMed ID: 25986851
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.
    Biochem Pharmacol; 2016 Jun 01; 109():27-47. PubMed ID: 27059255
    [Abstract] [Full Text] [Related]

  • 5. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers.
    Zundell JA, Fukumoto T, Lin J, Fatkhudinov N, Nacarelli T, Kossenkov AV, Liu Q, Cassel J, Hu CA, Wu S, Zhang R.
    Cancer Res; 2021 Oct 15; 81(20):5325-5335. PubMed ID: 34548333
    [Abstract] [Full Text] [Related]

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  • 7. 17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes.
    Mielczarek-Lewandowska A, Sztiller-Sikorska M, Osrodek M, Czyz M, Hartman ML.
    Apoptosis; 2019 Aug 15; 24(7-8):596-611. PubMed ID: 30989459
    [Abstract] [Full Text] [Related]

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  • 9. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
    Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC.
    Sci Rep; 2016 Sep 16; 6():33353. PubMed ID: 27634301
    [Abstract] [Full Text] [Related]

  • 10. Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis.
    Jiang S, Yan C, Fang QC, Shao ML, Zhang YL, Liu Y, Deng YP, Shan B, Liu JQ, Li HT, Yang L, Zhou J, Dai Z, Liu Y, Jia WP.
    J Biol Chem; 2014 Oct 24; 289(43):29751-65. PubMed ID: 25170079
    [Abstract] [Full Text] [Related]

  • 11. Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.
    Ishibashi T, Morita S, Kishimoto S, Uraki S, Takeshima K, Furukawa Y, Inaba H, Ariyasu H, Iwakura H, Furuta H, Nishi M, Papa FR, Akamizu T.
    J Diabetes Investig; 2020 Jul 24; 11(4):801-813. PubMed ID: 31925927
    [Abstract] [Full Text] [Related]

  • 12. Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
    Kharabi Masouleh B, Geng H, Hurtz C, Chan LN, Logan AC, Chang MS, Huang C, Swaminathan S, Sun H, Paietta E, Melnick AM, Koeffler P, Müschen M.
    Proc Natl Acad Sci U S A; 2014 May 27; 111(21):E2219-28. PubMed ID: 24821775
    [Abstract] [Full Text] [Related]

  • 13. XBP1: A Pivotal Transcriptional Regulator of Glucose and Lipid Metabolism.
    Piperi C, Adamopoulos C, Papavassiliou AG.
    Trends Endocrinol Metab; 2016 Mar 27; 27(3):119-122. PubMed ID: 26803729
    [Abstract] [Full Text] [Related]

  • 14. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
    Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
    J Clin Invest; 2015 Aug 03; 125(8):3269-79. PubMed ID: 26193638
    [Abstract] [Full Text] [Related]

  • 15. Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.
    Lara-Reyna S, Scambler T, Holbrook J, Wong C, Jarosz-Griffiths HH, Martinon F, Savic S, Peckham D, McDermott MF.
    Front Immunol; 2019 Aug 03; 10():1789. PubMed ID: 31428093
    [Abstract] [Full Text] [Related]

  • 16. The unfolded protein response components IRE1α and XBP1 promote human coronavirus infection.
    Oda JM, den Hartigh AB, Jackson SM, Tronco AR, Fink SL.
    mBio; 2023 Aug 31; 14(4):e0054023. PubMed ID: 37306512
    [Abstract] [Full Text] [Related]

  • 17. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
    Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A.
    Cancer Res; 2020 Jun 01; 80(11):2368-2379. PubMed ID: 32265225
    [Abstract] [Full Text] [Related]

  • 18. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability.
    Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, Chen H, Wang M, Ju Z, Cong YS.
    Nat Commun; 2017 Jan 27; 8():14186. PubMed ID: 28128204
    [Abstract] [Full Text] [Related]

  • 19. Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.
    Newbatt Y, Hardcastle A, McAndrew PC, Strover JA, Mirza A, Morgan GJ, Burke R, Davies FE, Collins I, van Montfort RL.
    J Biomol Screen; 2013 Mar 27; 18(3):298-308. PubMed ID: 23139381
    [Abstract] [Full Text] [Related]

  • 20. Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.
    Chien W, Ding LW, Sun QY, Torres-Fernandez LA, Tan SZ, Xiao J, Lim SL, Garg M, Lee KL, Kitajima S, Takao S, Leong WZ, Sun H, Tokatly I, Poellinger L, Gery S, Koeffler PH.
    Oncotarget; 2014 Jul 15; 5(13):4881-94. PubMed ID: 24952679
    [Abstract] [Full Text] [Related]


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