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Journal Abstract Search
362 related items for PubMed ID: 31400707
1. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors. Romagnoli R, Oliva P, Salvador MK, Camacho ME, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Grillo E, Bortolozzi R, Rruga F, Mariotto E, Viola G. Eur J Med Chem; 2019 Nov 01; 181():111577. PubMed ID: 31400707 [Abstract] [Full Text] [Related]
2. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents. Romagnoli R, Oliva P, Salvador MK, Manfredini S, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Rruga F, Mariotto E, Viola G, Bortolozzi R. Eur J Med Chem; 2021 Mar 15; 214():113229. PubMed ID: 33550186 [Abstract] [Full Text] [Related]
3. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition. Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G. Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790 [Abstract] [Full Text] [Related]
4. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors. Zhai M, Wang L, Liu S, Wang L, Yan P, Wang J, Zhang J, Guo H, Guan Q, Bao K, Wu Y, Zhang W. Eur J Med Chem; 2018 Aug 05; 156():137-147. PubMed ID: 30006160 [Abstract] [Full Text] [Related]
5. Synthesis and Biological Evaluation of 3-Alkyl-1,5-Diaryl-1H-Pyrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative Activity. Xu Q, Qi H, Sun M, Zuo D, Jiang X, Wen Z, Wang Z, Wu Y, Zhang W. PLoS One; 2015 Aug 05; 10(6):e0128710. PubMed ID: 26061410 [Abstract] [Full Text] [Related]
6. Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents. Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Salvador MK, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Porcù E, Basso G, Viola G. Sci Rep; 2017 Apr 13; 7():46356. PubMed ID: 28406191 [Abstract] [Full Text] [Related]
7. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors. Oliva P, Romagnoli R, Manfredini S, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Giacomini A, Rruga F, Mariotto E, Viola G, Bortolozzi R. Eur J Med Chem; 2020 Aug 15; 200():112448. PubMed ID: 32417696 [Abstract] [Full Text] [Related]
8. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues. Mustafa M, Abdelhamid D, Abdelhafez EMN, Ibrahim MAA, Gamal-Eldeen AM, Aly OM. Eur J Med Chem; 2017 Dec 01; 141():293-305. PubMed ID: 29031074 [Abstract] [Full Text] [Related]
9. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site. Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP. J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319 [Abstract] [Full Text] [Related]
10. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues. Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Brancale A, Hamel E, Chen L, Bortolozzi R, Basso G, Viola G. J Med Chem; 2010 May 27; 53(10):4248-58. PubMed ID: 20420439 [Abstract] [Full Text] [Related]
11. Isocombretastatins A: 1,1-diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds. Alvarez R, Alvarez C, Mollinedo F, Sierra BG, Medarde M, Peláez R. Bioorg Med Chem; 2009 Sep 01; 17(17):6422-31. PubMed ID: 19647439 [Abstract] [Full Text] [Related]
12. Novel cyanocombretastatins as potent tubulin polymerisation inhibitors. Jalily PH, Hadfield JA, Hirst N, Rossington SB. Bioorg Med Chem Lett; 2012 Nov 01; 22(21):6731-4. PubMed ID: 23010271 [Abstract] [Full Text] [Related]
13. Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents. Kamal A, Shaik AB, Rao BB, Khan I, Bharath Kumar G, Jain N. Org Biomol Chem; 2015 Oct 28; 13(40):10162-78. PubMed ID: 26303171 [Abstract] [Full Text] [Related]
14. Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole. Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Tabrizi MA, Lopez-Cara LC, Ferla S, Brancale A, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Basso G, Viola G. Sci Rep; 2016 May 24; 6():26602. PubMed ID: 27216165 [Abstract] [Full Text] [Related]
15. Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells. Álvarez R, Gajate C, Puebla P, Mollinedo F, Medarde M, Peláez R. Eur J Med Chem; 2018 Oct 05; 158():167-183. PubMed ID: 30216850 [Abstract] [Full Text] [Related]
16. Microwave-assisted synthesis and biological evaluation of 3,4-diaryl maleic anhydride/N-substituted maleimide derivatives as combretastatin A-4 analogues. Guan Q, Zuo D, Jiang N, Qi H, Zhai Y, Bai Z, Feng D, Yang L, Jiang M, Bao K, Li C, Wu Y, Zhang W. Bioorg Med Chem Lett; 2015 Feb 01; 25(3):631-4. PubMed ID: 25529737 [Abstract] [Full Text] [Related]
17. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors. Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W. Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171 [Abstract] [Full Text] [Related]
18. Thiazolidinone Constraint Combretastatin Analogs as Novel Antitubulin Agents: Design, Synthesis, Biological Evaluation and Docking Studies. Sharma S, Gupta MK, Saxena AK, Bedi PM. Anticancer Agents Med Chem; 2017 Dec 15; 17(2):230-240. PubMed ID: 27141882 [Abstract] [Full Text] [Related]
19. Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers. Subba Rao AV, Swapna K, Shaik SP, Lakshma Nayak V, Srinivasa Reddy T, Sunkari S, Shaik TB, Bagul C, Kamal A. Bioorg Med Chem; 2017 Feb 01; 25(3):977-999. PubMed ID: 28034647 [Abstract] [Full Text] [Related]
20. Correlation of hydrogen-bonding propensity and anticancer profile of tetrazole-tethered combretastatin analogues. Jedhe GS, Paul D, Gonnade RG, Santra MK, Hamel E, Nguyen TL, Sanjayan GJ. Bioorg Med Chem Lett; 2013 Aug 15; 23(16):4680-4. PubMed ID: 23809851 [Abstract] [Full Text] [Related] Page: [Next] [New Search]