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776 related items for PubMed ID: 31404628

  • 1. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
    Teng JF, Qin DL, Mei QB, Qiu WQ, Pan R, Xiong R, Zhao Y, Law BY, Wong VK, Tang Y, Yu CL, Zhang F, Wu JM, Wu AG.
    Pharmacol Res; 2019 Sep; 147():104396. PubMed ID: 31404628
    [Abstract] [Full Text] [Related]

  • 2. Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer.
    Teng JF, Mei QB, Zhou XG, Tang Y, Xiong R, Qiu WQ, Pan R, Law BY, Wong VK, Yu CL, Long HA, Xiao XL, Zhang F, Wu JM, Qin DL, Wu AG.
    Cancers (Basel); 2020 Jan 13; 12(1):. PubMed ID: 31941010
    [Abstract] [Full Text] [Related]

  • 3. Novel steroidal saponin isolated from Trillium tschonoskii maxim. exhibits anti-oxidative effect via autophagy induction in cellular and Caenorhabditis elegans models.
    Wu AG, Teng JF, Wong VK, Zhou XG, Qiu WQ, Tang Y, Wu JM, Xiong R, Pan R, Wang YL, Tang B, Ding TY, Yu L, Zeng W, Qin DL, Law BY.
    Phytomedicine; 2019 Dec 13; 65():153088. PubMed ID: 31627105
    [Abstract] [Full Text] [Related]

  • 4. Luteoloside induces G0/G1 arrest and pro-death autophagy through the ROS-mediated AKT/mTOR/p70S6K signalling pathway in human non-small cell lung cancer cell lines.
    Zhou M, Shen S, Zhao X, Gong X.
    Biochem Biophys Res Commun; 2017 Dec 09; 494(1-2):263-269. PubMed ID: 29024631
    [Abstract] [Full Text] [Related]

  • 5. A platycoside-rich fraction from the root of Platycodon grandiflorum enhances cell death in A549 human lung carcinoma cells via mainly AMPK/mTOR/AKT signal-mediated autophagy induction.
    Yim NH, Hwang YH, Liang C, Ma JY.
    J Ethnopharmacol; 2016 Dec 24; 194():1060-1068. PubMed ID: 27989873
    [Abstract] [Full Text] [Related]

  • 6. Paris saponin VII extracted from Trillium tschonoskii induces autophagy and apoptosis in NSCLC cells.
    Qian S, Tong S, Wu J, Tian L, Qi Z, Chen B, Zhu D, Zhang Y.
    J Ethnopharmacol; 2020 Feb 10; 248():112304. PubMed ID: 31626908
    [Abstract] [Full Text] [Related]

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  • 8. Pseudolaric acid B suppresses NSCLC progression through the ROS/AMPK/mTOR/autophagy signalling pathway.
    Luo D, He F, Liu J, Dong X, Fang M, Liang Y, Chen M, Gui X, Wang W, Zeng L, Fan X, Wu Q.
    Biomed Pharmacother; 2024 Jun 10; 175():116614. PubMed ID: 38670047
    [Abstract] [Full Text] [Related]

  • 9. Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
    Geng YD, Zhang C, Lei JL, Yu P, Xia YZ, Zhang H, Yang L, Kong LY.
    Biochem Pharmacol; 2017 Oct 15; 142():71-86. PubMed ID: 28673807
    [Abstract] [Full Text] [Related]

  • 10. Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling.
    Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, Han L, Xin X, Wang H, Lin D, Peng F, Yu F, Zheng C, Shen C.
    Cell Prolif; 2020 Aug 15; 53(8):e12869. PubMed ID: 32597573
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition.
    Feng FF, Cheng P, Sun C, Wang H, Wang W.
    Chin J Nat Med; 2019 Oct 15; 17(10):768-777. PubMed ID: 31703757
    [Abstract] [Full Text] [Related]

  • 12.
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  • 13. Anti-breast cancer and toxicity studies of total secondary saponin from Anemone raddeana Rhizome on MCF-7 cells via ROS generation and PI3K/AKT/mTOR inactivation.
    Zhang D, Zhang Q, Zheng Y, Lu J.
    J Ethnopharmacol; 2020 Sep 15; 259():112984. PubMed ID: 32446927
    [Abstract] [Full Text] [Related]

  • 14. Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
    Zhou X, Yue GG, Chan AM, Tsui SK, Fung KP, Sun H, Pu J, Lau CB.
    Biochem Pharmacol; 2017 Oct 15; 142():58-70. PubMed ID: 28669564
    [Abstract] [Full Text] [Related]

  • 15. Hydroxysafflor yellow A inhibited lipopolysaccharide-induced non-small cell lung cancer cell proliferation, migration, and invasion by suppressing the PI3K/AKT/mTOR and ERK/MAPK signaling pathways.
    Jiang M, Zhou LY, Xu N, An Q.
    Thorac Cancer; 2019 Jun 15; 10(6):1319-1333. PubMed ID: 31055884
    [Abstract] [Full Text] [Related]

  • 16. Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway.
    Zheng R, Jiang H, Li J, Liu X, Xu H.
    Curr Cancer Drug Targets; 2017 Jun 15; 17(4):376-385. PubMed ID: 28093061
    [Abstract] [Full Text] [Related]

  • 17. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY, Hwangbo H, Kim MY, Ji SY, Lee H, Kim GY, Kwon CY, Leem SH, Hong SH, Cheong J, Choi YH.
    Arch Biochem Biophys; 2021 Jan 15; 697():108688. PubMed ID: 33227289
    [Abstract] [Full Text] [Related]

  • 18. SC-III3, a novel scopoletin derivative, induces autophagy of human hepatoma HepG2 cells through AMPK/mTOR signaling pathway by acting on mitochondria.
    Zhao P, Dou Y, Chen L, Li L, Wei Z, Yu J, Wu X, Dai Y, Xia Y.
    Fitoterapia; 2015 Jul 15; 104():31-40. PubMed ID: 25964188
    [Abstract] [Full Text] [Related]

  • 19. PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.
    Ling YH, Aracil M, Zou Y, Yuan Z, Lu B, Jimeno J, Cuervo AM, Perez-Soler R.
    Clin Cancer Res; 2011 Aug 15; 17(16):5353-66. PubMed ID: 21690574
    [Abstract] [Full Text] [Related]

  • 20. Aloe-emodin induces autophagy and apoptotic cell death in non-small cell lung cancer cells via Akt/mTOR and MAPK signaling.
    Shen F, Ge C, Yuan P.
    Eur J Pharmacol; 2020 Nov 05; 886():173550. PubMed ID: 32926915
    [Abstract] [Full Text] [Related]

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