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6. Is 2-propyl-4-pentenoic acid, a hepatotoxic metabolite of valproate, responsible for valproate-induced hyperammonemia? Kondo T, Ishida M, Kaneko S, Hirano T, Otani K, Fukushima Y, Muranaka H, Koide N, Yokoyama M, Nakata S. Epilepsia; 1992; 33(3):550-4. PubMed ID: 1350534 [Abstract] [Full Text] [Related]
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10. Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status. Tang W, Borel AG, Fujimiya T, Abbott FS. Chem Res Toxicol; 1995 Feb 14; 8(5):671-82. PubMed ID: 7548749 [Abstract] [Full Text] [Related]
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13. Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity. Siemes H, Nau H, Schultze K, Wittfoht W, Drews E, Penzien J, Seidel U. Epilepsia; 1993 Apr 14; 34(2):332-46. PubMed ID: 8453944 [Abstract] [Full Text] [Related]
14. Capillary GCMS assay of 2-n-propyl-4-pentenoic acid (4-ene VPA) in rat plasma and urine. Singh K, Abbott FS, Orr JM. Res Commun Chem Pathol Pharmacol; 1987 May 14; 56(2):211-23. PubMed ID: 3602586 [Abstract] [Full Text] [Related]
15. A comparative investigation of 2-propyl-4-pentenoic acid (4-ene VPA) and its alpha-fluorinated analogue: phase II metabolism and pharmacokinetics. Tang W, Abbott FS. Drug Metab Dispos; 1997 Feb 14; 25(2):219-27. PubMed ID: 9029053 [Abstract] [Full Text] [Related]
16. In vivo formation of the thiol conjugates of reactive metabolites of 4-ene VPA and its analog 4-pentenoic acid. Kassahun K, Abbott F. Drug Metab Dispos; 1993 Feb 14; 21(6):1098-106. PubMed ID: 7905390 [Abstract] [Full Text] [Related]
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19. Valproate and carbamazepine comedication changes hepatic enzyme activities in sera of epileptic children. Cepelak I, Zanić Grubisić T, Mandusić A, Rekić B, Lenicek J. Clin Chim Acta; 1998 Aug 28; 276(2):121-7. PubMed ID: 9764730 [Abstract] [Full Text] [Related]