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316 related items for PubMed ID: 31437157

  • 1. Proprotein convertase subtilisin/kexin type 9 (PCSK9) in Alzheimer's disease: A genetic and proteomic multi-cohort study.
    Picard C, Poirier A, Bélanger S, Labonté A, Auld D, Poirier J, PREVENT-AD Research Group.
    PLoS One; 2019; 14(8):e0220254. PubMed ID: 31437157
    [Abstract] [Full Text] [Related]

  • 2. Increased PCSK9 Cerebrospinal Fluid Concentrations in Alzheimer's Disease.
    Zimetti F, Caffarra P, Ronda N, Favari E, Adorni MP, Zanotti I, Bernini F, Barocco F, Spallazzi M, Galimberti D, Ricci C, Ruscica M, Corsini A, Ferri N.
    J Alzheimers Dis; 2017; 55(1):315-320. PubMed ID: 27662294
    [Abstract] [Full Text] [Related]

  • 3. The Effect of PCSK9 Loss-of-Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response.
    Ooi TC, Krysa JA, Chaker S, Abujrad H, Mayne J, Henry K, Cousins M, Raymond A, Favreau C, Taljaard M, Chrétien M, Mbikay M, Proctor SD, Vine DF.
    J Clin Endocrinol Metab; 2017 Sep 01; 102(9):3452-3460. PubMed ID: 28673045
    [Abstract] [Full Text] [Related]

  • 4. Cyclase-associated protein 1 is a binding partner of proprotein convertase subtilisin/kexin type-9 and is required for the degradation of low-density lipoprotein receptors by proprotein convertase subtilisin/kexin type-9.
    Jang HD, Lee SE, Yang J, Lee HC, Shin D, Lee H, Lee J, Jin S, Kim S, Lee SJ, You J, Park HW, Nam KY, Lee SH, Park SW, Kim JS, Kim SY, Kwon YW, Kwak SH, Yang HM, Kim HS.
    Eur Heart J; 2020 Jan 07; 41(2):239-252. PubMed ID: 31419281
    [Abstract] [Full Text] [Related]

  • 5. Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice.
    Sun L, Yang X, Li Q, Zeng P, Liu Y, Liu L, Chen Y, Yu M, Ma C, Li X, Li Y, Zhang R, Zhu Y, Miao QR, Han J, Duan Y.
    Arterioscler Thromb Vasc Biol; 2017 Jul 07; 37(7):1290-1300. PubMed ID: 28546220
    [Abstract] [Full Text] [Related]

  • 6. PCSK9 Concentrations in Cerebrospinal Fluid Are Not Specifically Increased in Alzheimer's Disease.
    Courtemanche H, Bigot E, Pichelin M, Guyomarch B, Boutoleau-Bretonnière C, Le May C, Derkinderen P, Cariou B.
    J Alzheimers Dis; 2018 Jul 07; 62(4):1519-1525. PubMed ID: 29562508
    [Abstract] [Full Text] [Related]

  • 7. Posttranslational modification of proprotein convertase subtilisin/kexin type 9 is differentially regulated in response to distinct cardiometabolic treatments as revealed by targeted proteomics.
    Gauthier MS, Awan Z, Bouchard A, Champagne J, Tessier S, Faubert D, Chabot K, Garneau PY, Rabasa-Lhoret R, Seidah NG, Ridker PM, Genest J, Coulombe B.
    J Clin Lipidol; 2018 Jul 07; 12(4):1027-1038. PubMed ID: 29699916
    [Abstract] [Full Text] [Related]

  • 8. Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor.
    Sun H, Samarghandi A, Zhang N, Yao Z, Xiong M, Teng BB.
    Arterioscler Thromb Vasc Biol; 2012 Jul 07; 32(7):1585-95. PubMed ID: 22580899
    [Abstract] [Full Text] [Related]

  • 9. ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderly.
    Slot RER, Kester MI, Van Harten AC, Jongbloed W, Bouwman FH, Teunissen CE, Scheltens P, van der Flier WM, Veerhuis R.
    Neurobiol Aging; 2019 Jul 07; 79():101-109. PubMed ID: 31029938
    [Abstract] [Full Text] [Related]

  • 10. Proprotein Convertase Subtilisin/Kexin Type 9 Loss-of-Function Is Detrimental to the Juvenile Host With Septic Shock.
    Atreya MR, Whitacre BE, Cvijanovich NZ, Bigham MT, Thomas NJ, Schwarz AJ, Weiss SL, Fitzgerald JC, Allen GL, Lutfi R, Nowak JE, Quasney MW, Shah AS, Wong HR.
    Crit Care Med; 2020 Oct 07; 48(10):1513-1520. PubMed ID: 32769621
    [Abstract] [Full Text] [Related]

  • 11. Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms.
    Rashid S, Tavori H, Brown PE, Linton MF, He J, Giunzioni I, Fazio S.
    Circulation; 2014 Jul 29; 130(5):431-41. PubMed ID: 25070550
    [Abstract] [Full Text] [Related]

  • 12. Beyond LDL: What Role for PCSK9 in Triglyceride-Rich Lipoprotein Metabolism?
    Dijk W, Le May C, Cariou B.
    Trends Endocrinol Metab; 2018 Jun 29; 29(6):420-434. PubMed ID: 29665987
    [Abstract] [Full Text] [Related]

  • 13. Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town.
    Huijgen R, Blom DJ, Hartgers ML, Chemello K, Benito-Vicente A, Uribe KB, Behardien Z, Blackhurst DM, Brice BC, Defesche JC, de Jong AG, Jooste RJ, Solomon GAE, Wolmarans KH, Hovingh GK, Martin C, Lambert G, Marais AD.
    Arterioscler Thromb Vasc Biol; 2021 Feb 29; 41(2):934-943. PubMed ID: 33147992
    [Abstract] [Full Text] [Related]

  • 14. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease.
    Cruchaga C, Kauwe JS, Mayo K, Spiegel N, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MM, Williams J, Lovestone S, Peskind ER, Li G, Leverenz JB, Galasko D, Alzheimer's Disease Neuroimaging Initiative, Morris JC, Fagan AM, Holtzman DM, Goate AM.
    PLoS Genet; 2010 Sep 16; 6(9):e1001101. PubMed ID: 20862329
    [Abstract] [Full Text] [Related]

  • 15. Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.
    Elias-Sonnenschein LS, Helisalmi S, Natunen T, Hall A, Paajanen T, Herukka SK, Laitinen M, Remes AM, Koivisto AM, Mattila KM, Lehtimäki T, Verhey FR, Visser PJ, Soininen H, Hiltunen M.
    PLoS One; 2013 Sep 16; 8(4):e59676. PubMed ID: 23573206
    [Abstract] [Full Text] [Related]

  • 16. PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.
    Ason B, van der Hoorn JW, Chan J, Lee E, Pieterman EJ, Nguyen KK, Di M, Shetterly S, Tang J, Yeh WC, Schwarz M, Jukema JW, Scott R, Wasserman SM, Princen HM, Jackson S.
    J Lipid Res; 2014 Nov 16; 55(11):2370-9. PubMed ID: 25258384
    [Abstract] [Full Text] [Related]

  • 17. Enhanced pro-protein convertase subtilisin/kexin type 9 expression by C-reactive protein through p38MAPK-HNF1α pathway in HepG2 cells.
    Cui CJ, Li S, Zhu CG, Sun J, Du Y, Zhang Y, Wu NQ, Guo YL, Xu RX, Gao Y, Li JJ.
    J Cell Mol Med; 2016 Dec 16; 20(12):2374-2383. PubMed ID: 27633999
    [Abstract] [Full Text] [Related]

  • 18. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation.
    Weider E, Susan-Resiga D, Essalmani R, Hamelin J, Asselin MC, Nimesh S, Ashraf Y, Wycoff KL, Zhang J, Prat A, Seidah NG.
    J Biol Chem; 2016 Aug 05; 291(32):16659-71. PubMed ID: 27284008
    [Abstract] [Full Text] [Related]

  • 19. Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis.
    Pott J, Kheirkhah A, Gadin JR, Kleber ME, Delgado GE, Kirsten H, Forer L, Hauck SM, Burkhardt R, Scharnagl H, Loeffler M, März W, Thiery J, Gieger C, Peters A, Silveira A, Hooft FV, Kronenberg F, Scholz M.
    Biol Sex Differ; 2024 Mar 26; 15(1):26. PubMed ID: 38532495
    [Abstract] [Full Text] [Related]

  • 20. Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers.
    Ramos de Matos M, Ferreira C, Herukka SK, Soininen H, Janeiro A, Santana I, Baldeiras I, Almeida MR, Lleó A, Dols-Icardo O, Alcolea D, Benussi L, Binetti G, Paterlini A, Ghidoni R, Nacmias B, Meulenbroek O, van Waalwijk van Doorn LJC, Kuiperi HBJ, Hausner L, Waldemar G, Simonsen AH, Tsolaki M, Gkatzima O, Resende de Oliveira C, Verbeek MM, Clarimon J, Hiltunen M, de Mendonça A, Martins M.
    J Alzheimers Dis; 2018 Mar 26; 66(2):639-652. PubMed ID: 30320580
    [Abstract] [Full Text] [Related]

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