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219 related items for PubMed ID: 31438541

  • 1. Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation.
    Kim EK, Kim JH, Jeong S, Choi YW, Choi HJ, Kim CY, Kim YM.
    Int J Mol Sci; 2019 Aug 21; 20(17):. PubMed ID: 31438541
    [Abstract] [Full Text] [Related]

  • 2. Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β.
    Song JS, Kim EK, Choi YW, Oh WK, Kim YM.
    Toxicol Appl Pharmacol; 2016 Sep 15; 307():138-149. PubMed ID: 27511913
    [Abstract] [Full Text] [Related]

  • 3. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation.
    Han JY, Cho SS, Yang JH, Kim KM, Jang CH, Park DE, Bang JS, Jung YS, Ki SH.
    Toxicol Appl Pharmacol; 2015 Aug 15; 287(1):77-85. PubMed ID: 26028482
    [Abstract] [Full Text] [Related]

  • 4. Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
    Yang JH, Shin BY, Han JY, Kim MG, Wi JE, Kim YW, Cho IJ, Kim SC, Shin SM, Ki SH.
    Toxicol Appl Pharmacol; 2014 Jan 15; 274(2):293-301. PubMed ID: 24211276
    [Abstract] [Full Text] [Related]

  • 5. Oxyresveratrol abrogates oxidative stress by activating ERK-Nrf2 pathway in the liver.
    Choi HY, Lee JH, Jegal KH, Cho IJ, Kim YW, Kim SC.
    Chem Biol Interact; 2016 Feb 05; 245():110-21. PubMed ID: 26102008
    [Abstract] [Full Text] [Related]

  • 6. Protective Effects of Maillard Reaction Products of Whey Protein Concentrate against Oxidative Stress through an Nrf2-Dependent Pathway in HepG2 Cells.
    Pyo MC, Yang SY, Chun SH, Oh NS, Lee KW.
    Biol Pharm Bull; 2016 Sep 01; 39(9):1437-47. PubMed ID: 27320783
    [Abstract] [Full Text] [Related]

  • 7. Isoliquiritigenin in licorice functions as a hepatic protectant by induction of antioxidant genes through extracellular signal-regulated kinase-mediated NF-E2-related factor-2 signaling pathway.
    Park SM, Lee JR, Ku SK, Cho IJ, Byun SH, Kim SC, Park SJ, Kim YW.
    Eur J Nutr; 2016 Dec 01; 55(8):2431-2444. PubMed ID: 26593436
    [Abstract] [Full Text] [Related]

  • 8. Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.
    Martín MA, Ramos S, Granado-Serrano AB, Rodríguez-Ramiro I, Trujillo M, Bravo L, Goya L.
    Mol Nutr Food Res; 2010 Jul 01; 54(7):956-66. PubMed ID: 20166143
    [Abstract] [Full Text] [Related]

  • 9. ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress.
    Yang SY, Pyo MC, Nam MH, Lee KW.
    BMC Complement Altern Med; 2019 Jun 20; 19(1):139. PubMed ID: 31221142
    [Abstract] [Full Text] [Related]

  • 10. Saeng-Kankunbi-Tang () protects liver against oxidative damage through activation of ERK/Nrf2 pathway.
    Lee IW, Choi HY, Lee JH, Park SD, Kim SM, Ku SK, Zhao RJ, Kim SC, Kim YW, Choi HS.
    Chin J Integr Med; 2016 Aug 20; 22(8):619-28. PubMed ID: 27299460
    [Abstract] [Full Text] [Related]

  • 11. tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation.
    Li S, Li J, Shen C, Zhang X, Sun S, Cho M, Sun C, Song Z.
    Biochim Biophys Acta; 2014 Jan 20; 1841(1):22-33. PubMed ID: 24055888
    [Abstract] [Full Text] [Related]

  • 12. Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway.
    Wang P, Peng X, Wei ZF, Wei FY, Wang W, Ma WD, Yao LP, Fu YJ, Zu YG.
    Biochim Biophys Acta; 2015 Sep 20; 1850(9):1751-61. PubMed ID: 25917210
    [Abstract] [Full Text] [Related]

  • 13. The cytoprotective effects of 7,8-dihydroxyflavone against oxidative stress are mediated by the upregulation of Nrf2-dependent HO-1 expression through the activation of the PI3K/Akt and ERK pathways in C2C12 myoblasts.
    Kang JS, Choi IW, Han MH, Kim GY, Hong SH, Park C, Hwang HJ, Kim CM, Kim BW, Choi YH.
    Int J Mol Med; 2015 Aug 20; 36(2):501-10. PubMed ID: 26096841
    [Abstract] [Full Text] [Related]

  • 14. Tryptanthrin protects hepatocytes against oxidative stress via activation of the extracellular signal-regulated kinase/NF-E2-related factor 2 pathway.
    Moon SY, Lee JH, Choi HY, Cho IJ, Kim SC, Kim YW.
    Biol Pharm Bull; 2014 Aug 20; 37(10):1633-40. PubMed ID: 25273386
    [Abstract] [Full Text] [Related]

  • 15. Ajoene, a stable garlic by-product, has an antioxidant effect through Nrf2-mediated glutamate-cysteine ligase induction in HepG2 cells and primary hepatocytes.
    Kay HY, Won Yang J, Kim TH, Lee DY, Kang B, Ryu JH, Jeon R, Kim SG.
    J Nutr; 2010 Jul 20; 140(7):1211-9. PubMed ID: 20463144
    [Abstract] [Full Text] [Related]

  • 16. Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.
    Feng RB, Wang Y, He C, Yang Y, Wan JB.
    Food Chem Toxicol; 2018 Sep 20; 119():479-488. PubMed ID: 29066411
    [Abstract] [Full Text] [Related]

  • 17. The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation.
    Xing HY, Cai YQ, Wang XF, Wang LL, Li P, Wang GY, Chen JH.
    PLoS One; 2015 Sep 20; 10(12):e0145183. PubMed ID: 26674355
    [Abstract] [Full Text] [Related]

  • 18. Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway.
    Zhang L, Zhang H, Li X, Jia B, Yang Y, Zhou P, Li P, Chen J.
    Phytomedicine; 2016 Dec 15; 23(14):1806-1813. PubMed ID: 27912883
    [Abstract] [Full Text] [Related]

  • 19. Cocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells.
    Martín MA, Serrano AB, Ramos S, Pulido MI, Bravo L, Goya L.
    J Nutr Biochem; 2010 Mar 15; 21(3):196-205. PubMed ID: 19195869
    [Abstract] [Full Text] [Related]

  • 20. Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress.
    Yang YC, Lii CK, Lin AH, Yeh YW, Yao HT, Li CC, Liu KL, Chen HW.
    Free Radic Biol Med; 2011 Dec 01; 51(11):2073-81. PubMed ID: 21964506
    [Abstract] [Full Text] [Related]

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