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130 related items for PubMed ID: 31466835

  • 1. Optimization and anti-inflammatory evaluation of methyl gallate derivatives as a myeloid differentiation protein 2 inhibitor.
    Qiu Y, Xiao Z, Wang Y, Zhang D, Zhang W, Wang G, Chen W, Liang G, Li X, Zhang Y, Liu Z.
    Bioorg Med Chem; 2019 Oct 15; 27(20):115049. PubMed ID: 31466835
    [Abstract] [Full Text] [Related]

  • 2. Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
    Chen L, Jin Y, Chen H, Sun C, Fu W, Zheng L, Lu M, Chen P, Chen G, Zhang Y, Liu Z, Wang Y, Song Z, Liang G.
    Eur J Med Chem; 2018 Jan 01; 143():361-375. PubMed ID: 29202400
    [Abstract] [Full Text] [Related]

  • 3. Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2.
    Zhang YL, Zhang WX, Yan JQ, Tang YL, Jia WJ, Xu ZW, Xu MJ, Chattipakorn N, Wang Y, Feng JP, Liu ZG, Liang G.
    Acta Pharmacol Sin; 2022 Jan 01; 43(1):76-85. PubMed ID: 34480112
    [Abstract] [Full Text] [Related]

  • 4. Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury.
    Chen G, Xiao B, Chen L, Bai B, Zhang Y, Xu Z, Fu L, Liu Z, Li X, Zhao Y, Liang G.
    Eur J Med Chem; 2017 Oct 20; 139():726-740. PubMed ID: 28858767
    [Abstract] [Full Text] [Related]

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  • 6. Targeting myeloid differentiation protein 2 by the new chalcone L2H21 protects LPS-induced acute lung injury.
    Zhang Y, Xu T, Wu B, Chen H, Pan Z, Huang Y, Mei L, Dai Y, Liu X, Shan X, Liang G.
    J Cell Mol Med; 2017 Apr 20; 21(4):746-757. PubMed ID: 27860279
    [Abstract] [Full Text] [Related]

  • 7. L6H9 attenuates LPS-induced acute lung injury in rats through targeting MD2.
    Wu P, Yan H, Qi J, Jia W, Zhang W, Yao D, Ding C, Zhang Y, Chen M, Cai X.
    Drug Dev Res; 2020 Feb 20; 81(1):85-92. PubMed ID: 31693211
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury.
    Chen H, Zhang Y, Zhang W, Liu H, Sun C, Zhang B, Bai B, Wu D, Xiao Z, Lum H, Zhou J, Chen R, Liang G.
    Phytomedicine; 2019 Oct 20; 63():152997. PubMed ID: 31254764
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  • 10. Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury.
    Zhang Y, Wu J, Ying S, Chen G, Wu B, Xu T, Liu Z, Liu X, Huang L, Shan X, Dai Y, Liang G.
    Sci Rep; 2016 Apr 27; 6():25130. PubMed ID: 27118147
    [Abstract] [Full Text] [Related]

  • 11. Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2/toll-like receptor 4 signaling activation.
    Zhang Y, Chen H, Zhang W, Cai Y, Shan P, Wu D, Zhang B, Liu H, Khan ZA, Liang G.
    Biochim Biophys Acta Mol Basis Dis; 2020 May 01; 1866(5):165683. PubMed ID: 31953218
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  • 14. Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury.
    Chen L, Chen H, Chen P, Zhang W, Wu C, Sun C, Luo W, Zheng L, Liu Z, Liang G.
    Eur J Med Chem; 2019 Jan 01; 161():22-38. PubMed ID: 30342423
    [Abstract] [Full Text] [Related]

  • 15. Shikonin inhibits myeloid differentiation protein 2 to prevent LPS-induced acute lung injury.
    Zhang Y, Xu T, Pan Z, Ge X, Sun C, Lu C, Chen H, Xiao Z, Zhang B, Dai Y, Liang G.
    Br J Pharmacol; 2018 Mar 01; 175(5):840-854. PubMed ID: 29243243
    [Abstract] [Full Text] [Related]

  • 16. Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid Differentiation Protein 2/Toll-like Receptor 4 Antagonists for Treatment of Acute Lung Injury.
    Liu Z, Chen L, Yu P, Zhang Y, Fang B, Wu C, Luo W, Chen X, Li C, Liang G.
    J Med Chem; 2019 Jun 13; 62(11):5453-5469. PubMed ID: 30998353
    [Abstract] [Full Text] [Related]

  • 17. Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2.
    Wang Y, Shan X, Dai Y, Jiang L, Chen G, Zhang Y, Wang Z, Dong L, Wu J, Guo G, Liang G.
    J Pharmacol Exp Ther; 2015 Jun 13; 353(3):539-50. PubMed ID: 25862641
    [Abstract] [Full Text] [Related]

  • 18. Anti-inflammatory action of Athyrium multidentatum extract suppresses the LPS-induced TLR4 signaling pathway.
    Han XZ, Ma R, Chen Q, Jin X, Jin YZ, An RB, Piao XM, Lian ML, Quan LH, Jiang J.
    J Ethnopharmacol; 2018 May 10; 217():220-227. PubMed ID: 29476961
    [Abstract] [Full Text] [Related]

  • 19. New MD2 inhibitors derived from curcumin with improved anti-inflammatory activity.
    Zhang Y, Liu Z, Wu J, Bai B, Chen H, Xiao Z, Chen L, Zhao Y, Lum H, Wang Y, Zhang H, Liang G.
    Eur J Med Chem; 2018 Mar 25; 148():291-305. PubMed ID: 29466778
    [Abstract] [Full Text] [Related]

  • 20. Licochalcone A protects against LPS-induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2).
    Zhu W, Wang M, Jin L, Yang B, Bai B, Mutsinze RN, Zuo W, Chattipakorn N, Huh JY, Liang G, Wang Y.
    Br J Pharmacol; 2023 Apr 25; 180(8):1114-1131. PubMed ID: 36480410
    [Abstract] [Full Text] [Related]

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