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288 related items for PubMed ID: 3146822
1. Characterization of a chimaeric plasminogen activator obtained by insertion of the second kringle structure of tissue-type plasminogen activator (amino acids 173 through 262) between residues Asp130 and Ser139 of urokinase-type plasminogen activator. Lijnen HR, Piérard L, Reff ME, Gheysen D. Thromb Res; 1988 Dec 01; 52(5):431-41. PubMed ID: 3146822 [Abstract] [Full Text] [Related]
2. Characterization of a recombinant fusion protein of the finger domain of tissue-type plasminogen activator with a truncated single chain urokinase-type plasminogen activator. Gheysen D, Lijnen HR, Piérard L, de Foresta F, Demarsin E, Jacobs P, De Wilde M, Bollen A, Collen D. J Biol Chem; 1987 Aug 25; 262(24):11779-84. PubMed ID: 3114253 [Abstract] [Full Text] [Related]
4. Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator. Nelles L, Lijnen HR, Collen D, Holmes WE. J Biol Chem; 1987 Aug 05; 262(22):10855-62. PubMed ID: 2956260 [Abstract] [Full Text] [Related]
6. Biochemical properties of conjugates of urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin. Dewerchin M, Lijnen HR, Van Hoef B, De Cock F, Collen D. Eur J Biochem; 1989 Oct 20; 185(1):141-9. PubMed ID: 2530085 [Abstract] [Full Text] [Related]
7. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160. Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D. Eur J Biochem; 1988 Nov 15; 177(3):575-82. PubMed ID: 2973984 [Abstract] [Full Text] [Related]
8. Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158. Nelles L, Lijnen HR, Collen D, Holmes WE. J Biol Chem; 1987 Apr 25; 262(12):5682-9. PubMed ID: 3106341 [Abstract] [Full Text] [Related]
9. Functional properties of a recombinant chimeric protein with combined thrombin inhibitory and plasminogen-activating potential. Lijnen HR, Wnendt S, Schneider J, Janocha E, Van Hoef B, Collen D, Steffens GJ. Eur J Biochem; 1995 Nov 15; 234(1):350-7. PubMed ID: 8529664 [Abstract] [Full Text] [Related]
10. Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator. Stump DC, Lijnen HR, Collen D. J Biol Chem; 1986 Dec 25; 261(36):17120-6. PubMed ID: 3097021 [Abstract] [Full Text] [Related]
11. Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator. Bakker AH, Nieuwenbroek NM, Verheijen JH. Protein Eng; 1995 Dec 25; 8(12):1295-1302. PubMed ID: 8869642 [Abstract] [Full Text] [Related]
12. Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase. Holvoet P, Laroche Y, Lijnen HR, Van Cauwenberge R, Demarsin E, Brouwers E, Matthyssens G, Collen D. J Biol Chem; 1991 Oct 15; 266(29):19717-24. PubMed ID: 1918077 [Abstract] [Full Text] [Related]
13. Biochemical properties of recombinant mutants of nonglycosylated single chain urokinase-type plasminogen activator. Li XK, Lijnen HR, Nelles L, Hu MH, Collen D. Biochim Biophys Acta; 1992 Sep 04; 1159(1):37-43. PubMed ID: 1390910 [Abstract] [Full Text] [Related]
14. Biochemical properties of recombinant single-chain urokinase-type plasminogen activator mutants with deletion of Asn2 through Phe157 and/or substitution of Cys279 with Ala. Lijnen HR, Li XK, Nelles L, Hu MH, Collen D. Eur J Biochem; 1992 Apr 15; 205(2):701-9. PubMed ID: 1533368 [Abstract] [Full Text] [Related]
15. Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase. Holvoet P, Laroche Y, Lijnen HR, Van Hoef B, Brouwers E, De Cock F, Lauwereys M, Gansemans Y, Collen D. Eur J Biochem; 1992 Dec 15; 210(3):945-52. PubMed ID: 1483477 [Abstract] [Full Text] [Related]
16. The mechanism of plasminogen activation and fibrin dissolution by single chain urokinase-type plasminogen activator in a plasma milieu in vitro. Lijnen HR, Van Hoef B, De Cock F, Collen D. Blood; 1989 May 15; 73(7):1864-72. PubMed ID: 2713507 [Abstract] [Full Text] [Related]
17. A monoclonal antibody specific for two-chain urokinase-type plasminogen activator. Application to the study of the mechanism of clot lysis with single-chain urokinase-type plasminogen activator in plasma. Declerck PJ, Lijnen HR, Verstreken M, Moreau H, Collen D. Blood; 1990 May 01; 75(9):1794-800. PubMed ID: 1691934 [Abstract] [Full Text] [Related]
18. Characterization of a recombinant chimeric plasminogen activator composed of a fibrin fragment-D-dimer-specific humanized monoclonal antibody and a truncated single-chain urokinase. Vandamme AM, Dewerchin M, Lijnen HR, Bernar H, Bulens F, Nelles L, Collen D. Eur J Biochem; 1992 Apr 01; 205(1):139-46. PubMed ID: 1313361 [Abstract] [Full Text] [Related]
19. Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator. Lijnen HR, Nelles L, Holmes WE, Collen D. J Biol Chem; 1988 Apr 25; 263(12):5594-8. PubMed ID: 2965704 [Abstract] [Full Text] [Related]
20. Purification and properties of a single-chain urokinase-type plasminogen activator form produced by subcultured human umbilical vein endothelial cells. Booyse FM, Lin PH, Traylor M, Bruce R. J Biol Chem; 1988 Oct 15; 263(29):15139-45. PubMed ID: 3170576 [Abstract] [Full Text] [Related] Page: [Next] [New Search]