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Journal Abstract Search

539 related items for PubMed ID: 31473433

  • 1.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 2. An Effective Virtual Screening Protocol To Identify Promising p53-MDM2 Inhibitors.
    Tortorella P, Laghezza A, Durante M, Gomez-Monterrey I, Bertamino A, Campiglia P, Loiodice F, Daniele S, Martini C, Agamennone M.
    J Chem Inf Model; 2016 Jun 27; 56(6):1216-27. PubMed ID: 27269808
    [Abstract] [Full Text] [Related]

  • 3. Integrated virtual screening and molecular dynamics simulation revealed promising drug candidates of p53-MDM2 interaction.
    Oyedele AK, Adelusi TI, Ogunlana AT, Adeyemi RO, Atanda OE, Babalola MO, Ashiru MA, Ayoola IJ, Boyenle ID.
    J Mol Model; 2022 May 10; 28(6):142. PubMed ID: 35536362
    [Abstract] [Full Text] [Related]

  • 4. Identification of High Affinity Non-Peptidic Small Molecule Inhibitors of MDM2-p53 Interactions through Structure-Based Virtual Screening Strategies.
    Bandaru S, Ponnala D, Lakkaraju C, Bhukya CK, Shaheen U, Nayarisseri A.
    Asian Pac J Cancer Prev; 2015 May 10; 16(9):3759-65. PubMed ID: 25987034
    [Abstract] [Full Text] [Related]

  • 5. Identification of antipsychotic drug fluspirilene as a potential p53-MDM2 inhibitor: a combined computational and experimental study.
    Patil SP, Pacitti MF, Gilroy KS, Ruggiero JC, Griffin JD, Butera JJ, Notarfrancesco JM, Tran S, Stoddart JW.
    J Comput Aided Mol Des; 2015 Feb 10; 29(2):155-63. PubMed ID: 25377899
    [Abstract] [Full Text] [Related]

  • 6. Molecular interaction fields and 3D-QSAR studies of p53-MDM2 inhibitors suggest additional features of ligand-target interaction.
    Dezi C, Carotti A, Magnani M, Baroni M, Padova A, Cruciani G, Macchiarulo A, Pellicciari R.
    J Chem Inf Model; 2010 Aug 23; 50(8):1451-65. PubMed ID: 20726601
    [Abstract] [Full Text] [Related]

  • 7. Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay.
    Golestanian S, Sharifi A, Popowicz GM, Azizian H, Foroumadi A, Szwagierczak A, Holak TA, Amanlou M.
    Life Sci; 2016 Jan 15; 145():240-6. PubMed ID: 26746660
    [Abstract] [Full Text] [Related]

  • 8. Effective screening strategy using ensembled pharmacophore models combined with cascade docking: application to p53-MDM2 interaction inhibitors.
    Xue X, Wei JL, Xu LL, Xi MY, Xu XL, Liu F, Guo XK, Wang L, Zhang XJ, Zhang MY, Lu MC, Sun HP, You QD.
    J Chem Inf Model; 2013 Oct 28; 53(10):2715-29. PubMed ID: 24050442
    [Abstract] [Full Text] [Related]

  • 9. Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach.
    Zaytsev A, Dodd B, Magnani M, Ghiron C, Golding BT, Griffin RJ, Liu J, Lu X, Micco I, Newell DR, Padova A, Robertson G, Lunec J, Hardcastle IR.
    Chem Biol Drug Des; 2015 Aug 28; 86(2):180-9. PubMed ID: 25388787
    [Abstract] [Full Text] [Related]

  • 10. Identification of new inhibitors of Mdm2-p53 interaction via pharmacophore and structure-based virtual screening.
    Atatreh N, Ghattas MA, Bardaweel SK, Rawashdeh SA, Sorkhy MA.
    Drug Des Devel Ther; 2018 Aug 28; 12():3741-3752. PubMed ID: 30464405
    [Abstract] [Full Text] [Related]

  • 11. An Application of Fit Quality to Screen MDM2/p53 Protein-Protein Interaction Inhibitors.
    Xue X, Bao G, Zhang HQ, Zhao NY, Sun Y, Zhang Y, Wang XL.
    Molecules; 2018 Dec 01; 23(12):. PubMed ID: 30513790
    [Abstract] [Full Text] [Related]

  • 12. How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures.
    Estrada-Ortiz N, Neochoritis CG, Dömling A.
    ChemMedChem; 2016 Apr 19; 11(8):757-72. PubMed ID: 26676832
    [Abstract] [Full Text] [Related]

  • 13. Prospective virtual screening for novel p53-MDM2 inhibitors using ultrafast shape recognition.
    Patil SP, Ballester PJ, Kerezsi CR.
    J Comput Aided Mol Des; 2014 Feb 19; 28(2):89-97. PubMed ID: 24554192
    [Abstract] [Full Text] [Related]

  • 14. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.
    Zhao Y, Aguilar A, Bernard D, Wang S.
    J Med Chem; 2015 Feb 12; 58(3):1038-52. PubMed ID: 25396320
    [Abstract] [Full Text] [Related]

  • 15. Ensemble-based virtual screening reveals dual-inhibitors for the p53-MDM2/MDMX interactions.
    Barakat K, Mane J, Friesen D, Tuszynski J.
    J Mol Graph Model; 2010 Feb 26; 28(6):555-68. PubMed ID: 20056466
    [Abstract] [Full Text] [Related]

  • 16. The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy.
    Liao G, Yang D, Ma L, Li W, Hu L, Zeng L, Wu P, Duan L, Liu Z.
    Eur J Med Chem; 2018 Nov 05; 159():1-9. PubMed ID: 30253242
    [Abstract] [Full Text] [Related]

  • 17. Computational-based drug design of novel small molecules targeting p53-MDMX interaction.
    Egbemhenghe AU, Aderemi OE, Omotara BS, Akhimien FI, Osabuohien FO, Adedapo HA, Temionu OR, Egejuru WA, Ajala CF, Ihunanya MF, Oluwafemi OO, Onu CFD, Ajibare AC, Ddamulira C, Abalum JO, Afolayan OM.
    J Biomol Struct Dyn; 2024 Aug 05; 42(13):6678-6687. PubMed ID: 37578044
    [Abstract] [Full Text] [Related]

  • 18. Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.
    Gupta AK, Bharadwaj M, Kumar A, Mehrotra R.
    Top Curr Chem (Cham); 2017 Feb 05; 375(1):3. PubMed ID: 27943171
    [Abstract] [Full Text] [Related]

  • 19. Proposing novel MDM2 inhibitors: Combined physics-driven high-throughput virtual screening and in vitro studies.
    Aydin G, Paksoy MN, Orhan MD, Avsar T, Yurtsever M, Durdagi S.
    Chem Biol Drug Des; 2020 Jul 05; 96(1):684-700. PubMed ID: 32691963
    [Abstract] [Full Text] [Related]

  • 20. Small molecule inhibitors of the p53-MDM2.
    Hu CQ, Hu YZ.
    Curr Med Chem; 2008 Jul 05; 15(17):1720-30. PubMed ID: 18673221
    [Abstract] [Full Text] [Related]

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