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Journal Abstract Search

310 related items for PubMed ID: 31479304

  • 1. Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity.
    Fernández-Díaz CM, Merino B, López-Acosta JF, Cidad P, de la Fuente MA, Lobatón CD, Moreno A, Leissring MA, Perdomo G, Cózar-Castellano I.
    Am J Physiol Endocrinol Metab; 2019 Nov 01; 317(5):E805-E819. PubMed ID: 31479304
    [Abstract] [Full Text] [Related]

  • 2. Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation.
    Merino B, Casanueva-Álvarez E, Quesada I, González-Casimiro CM, Fernández-Díaz CM, Postigo-Casado T, Leissring MA, Kaestner KH, Perdomo G, Cózar-Castellano I.
    Diabetologia; 2022 Aug 01; 65(8):1375-1389. PubMed ID: 35652923
    [Abstract] [Full Text] [Related]

  • 3. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC.
    Diabetologia; 2019 Dec 01; 62(12):2273-2286. PubMed ID: 31624901
    [Abstract] [Full Text] [Related]

  • 4. Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance.
    Abdul-Hay SO, Kang D, McBride M, Li L, Zhao J, Leissring MA.
    PLoS One; 2011 Dec 01; 6(6):e20818. PubMed ID: 21695259
    [Abstract] [Full Text] [Related]

  • 5. Insulin degrading enzyme is up-regulated in pancreatic β cells by insulin treatment.
    Fernández-Díaz CM, Escobar-Curbelo L, López-Acosta JF, Lobatón CD, Moreno A, Sanz-Ortega J, Perdomo G, Cózar-Castellano I.
    Histol Histopathol; 2018 Nov 01; 33(11):1167-1180. PubMed ID: 29726577
    [Abstract] [Full Text] [Related]

  • 6. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
    Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR.
    Nature; 2014 Jul 03; 511(7507):94-8. PubMed ID: 24847884
    [Abstract] [Full Text] [Related]

  • 7. Loss of postprandial insulin clearance control by Insulin-degrading enzyme drives dysmetabolism traits.
    Borges DO, Patarrão RS, Ribeiro RT, de Oliveira RM, Duarte N, Belew GD, Martins M, Andrade R, Costa J, Correia I, Boavida JM, Duarte R, Gardete-Correia L, Medina JL, Raposo JF, Jones JG, Penha-Gonçalves C, Macedo MP.
    Metabolism; 2021 May 03; 118():154735. PubMed ID: 33631143
    [Abstract] [Full Text] [Related]

  • 8. Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice.
    Villa-Pérez P, Merino B, Fernández-Díaz CM, Cidad P, Lobatón CD, Moreno A, Muturi HT, Ghadieh HE, Najjar SM, Leissring MA, Cózar-Castellano I, Perdomo G.
    Metabolism; 2018 Nov 03; 88():1-11. PubMed ID: 30098324
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.
    Sanz-González A, Cózar-Castellano I, Broca C, Sabatier J, Acosta GA, Royo M, Hernándo-Muñoz C, Torroba T, Perdomo G, Merino B.
    Diabetes Obes Metab; 2023 Nov 03; 25(11):3268-3278. PubMed ID: 37493025
    [Abstract] [Full Text] [Related]

  • 10. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S.
    Proc Natl Acad Sci U S A; 2003 Apr 01; 100(7):4162-7. PubMed ID: 12634421
    [Abstract] [Full Text] [Related]

  • 11. Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
    Hoang M, Jentz E, Janssen SM, Nasteska D, Cuozzo F, Hodson DJ, Tupling AR, Fong GH, Joseph JW.
    Endocrinology; 2022 Jan 01; 163(1):. PubMed ID: 34718519
    [Abstract] [Full Text] [Related]

  • 12. Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice.
    Merino B, Fernández-Díaz CM, Parrado-Fernández C, González-Casimiro CM, Postigo-Casado T, Lobatón CD, Leissring MA, Cózar-Castellano I, Perdomo G.
    Metabolism; 2020 Dec 01; 113():154352. PubMed ID: 32916153
    [Abstract] [Full Text] [Related]

  • 13. Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells.
    Turk J, Song H, Wohltmann M, Frankfater C, Lei X, Ramanadham S.
    Biomolecules; 2020 Oct 17; 10(10):. PubMed ID: 33080873
    [Abstract] [Full Text] [Related]

  • 14. The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.
    Steneberg P, Bernardo L, Edfalk S, Lundberg L, Backlund F, Ostenson CG, Edlund H.
    Diabetes; 2013 Jun 17; 62(6):2004-14. PubMed ID: 23349488
    [Abstract] [Full Text] [Related]

  • 15. Reduced insulin sensitivity and increased β/α cell mass is associated with reduced hepatic insulin-degrading enzyme activity in pregnant rats.
    Taschetto APD, Zimath PL, Silvério R, Dos Santos C, Boschero AC, Dos Santos GJ, Rafacho A.
    Life Sci; 2021 Jul 15; 277():119509. PubMed ID: 33865877
    [Abstract] [Full Text] [Related]

  • 16. Normal β-Cell Glut2 Expression Is not Required for Regulating Glucose-Stimulated Insulin Secretion and Systemic Glucose Homeostasis in Mice.
    Bathina S, Faniyan TS, Bainbridge L, Davis A, Chhabra KH.
    Biomolecules; 2023 Mar 16; 13(3):. PubMed ID: 36979475
    [Abstract] [Full Text] [Related]

  • 17. Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and β-cell function: In vitro studies using INS-1 cells and human pancreatic islets.
    Taneera J, Khalique A, Abdrabh S, Mohammed AK, Bouzid A, El-Huneidi W, Bustanji Y, Sulaiman N, Albasha S, Saber-Ayad M, Hamad M.
    Life Sci; 2024 Feb 15; 339():122421. PubMed ID: 38232799
    [Abstract] [Full Text] [Related]

  • 18. Procyanidins modify insulinemia by affecting insulin production and degradation.
    Castell-Auví A, Cedó L, Pallarès V, Blay MT, Pinent M, Motilva MJ, Garcia-Vallvé S, Pujadas G, Maechler P, Ardévol A.
    J Nutr Biochem; 2012 Dec 15; 23(12):1565-72. PubMed ID: 22444499
    [Abstract] [Full Text] [Related]

  • 19. Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice.
    Han S, Englander EW, Gomez GA, Rastellini C, Quertermous T, Kundu RK, Greeley GH.
    Endocrinology; 2015 Jul 15; 156(7):2451-60. PubMed ID: 25965959
    [Abstract] [Full Text] [Related]

  • 20. Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function.
    Bauchle CJ, Rohli KE, Boyer CK, Pal V, Rocheleau JV, Liu S, Imai Y, Taylor EB, Stephens SB.
    Diabetes; 2021 Aug 15; 70(8):1717-1728. PubMed ID: 34039628
    [Abstract] [Full Text] [Related]

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