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Journal Abstract Search

416 related items for PubMed ID: 31486323

  • 1. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N, Martinez CA, Kerr B, Zaiter SS, Morgan M, McAlpine SR, Cook KM.
    Cell Physiol Biochem; 2019; 53(3):480-495. PubMed ID: 31486323
    [Abstract] [Full Text] [Related]

  • 2. RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization.
    Liu YV, Semenza GL.
    Cell Cycle; 2007 Mar 15; 6(6):656-9. PubMed ID: 17361105
    [Abstract] [Full Text] [Related]

  • 3. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K, Seo S, Ki SH, Shin SM.
    Free Radic Biol Med; 2016 Dec 15; 101():511-523. PubMed ID: 27840318
    [Abstract] [Full Text] [Related]

  • 4. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J, Schmid T, Frank R, Brüne B.
    J Biol Chem; 2004 Apr 02; 279(14):13506-13. PubMed ID: 14726529
    [Abstract] [Full Text] [Related]

  • 5. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X, Yao J, Wang F, Zhou M, Zhou Y, Wang H, Wei L, Zhao L, Li Z, Lu N, Guo Q.
    Toxicol Appl Pharmacol; 2013 Sep 01; 271(2):144-55. PubMed ID: 23707765
    [Abstract] [Full Text] [Related]

  • 6. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
    Liu YV, Baek JH, Zhang H, Diez R, Cole RN, Semenza GL.
    Mol Cell; 2007 Jan 26; 25(2):207-17. PubMed ID: 17244529
    [Abstract] [Full Text] [Related]

  • 7. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
    Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL.
    J Biol Chem; 2007 Dec 21; 282(51):37064-73. PubMed ID: 17965024
    [Abstract] [Full Text] [Related]

  • 8. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.
    Han JY, Oh SH, Morgillo F, Myers JN, Kim E, Hong WK, Lee HY.
    J Natl Cancer Inst; 2005 Sep 07; 97(17):1272-86. PubMed ID: 16145048
    [Abstract] [Full Text] [Related]

  • 9. Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
    Trisciuoglio D, Gabellini C, Desideri M, Ziparo E, Zupi G, Del Bufalo D.
    PLoS One; 2010 Jul 27; 5(7):e11772. PubMed ID: 20668552
    [Abstract] [Full Text] [Related]

  • 10. Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha.
    Baek JH, Liu YV, McDonald KR, Wesley JB, Zhang H, Semenza GL.
    J Biol Chem; 2007 Nov 16; 282(46):33358-33366. PubMed ID: 17875644
    [Abstract] [Full Text] [Related]

  • 11. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
    Jung DB, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim YC, Ahn KS, Chen CY, Kim SH.
    Biol Pharm Bull; 2011 Nov 16; 34(6):850-5. PubMed ID: 21628883
    [Abstract] [Full Text] [Related]

  • 12. Dimethyl fumarate inhibits the expression and function of hypoxia-inducible factor-1α (HIF-1α).
    Zhao G, Liu Y, Fang J, Chen Y, Li H, Gao K.
    Biochem Biophys Res Commun; 2014 Jun 06; 448(3):303-7. PubMed ID: 24569076
    [Abstract] [Full Text] [Related]

  • 13. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    Barliya T, Mandel M, Livnat T, Weinberger D, Lavie G.
    PLoS One; 2011 Jun 06; 6(9):e22849. PubMed ID: 21949677
    [Abstract] [Full Text] [Related]

  • 14. DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
    Kang MJ, Jung SM, Kim MJ, Bae JH, Kim HB, Kim JY, Park SJ, Song HS, Kim DW, Kang CD, Kim SH.
    FEBS J; 2008 Dec 06; 275(23):5969-81. PubMed ID: 19021771
    [Abstract] [Full Text] [Related]

  • 15. Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
    Lin HC, Su SL, Lu CY, Lin AH, Lin WC, Liu CS, Yang YC, Wang HM, Lii CK, Chen HW.
    Environ Toxicol; 2017 Mar 06; 32(3):918-930. PubMed ID: 27297870
    [Abstract] [Full Text] [Related]

  • 16. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
    Katschinski DM, Le L, Schindler SG, Thomas T, Voss AK, Wenger RH.
    Cell Physiol Biochem; 2004 Mar 06; 14(4-6):351-60. PubMed ID: 15319539
    [Abstract] [Full Text] [Related]

  • 17. Activation of hypoxia-induced transcription in normoxia.
    Hägg M, Wennström S.
    Exp Cell Res; 2005 May 15; 306(1):180-91. PubMed ID: 15878343
    [Abstract] [Full Text] [Related]

  • 18. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1α.
    Yang F, Cai J, Zhan H, Situ J, Li W, Mao Y, Luo Y.
    Oxid Med Cell Longev; 2020 May 15; 2020():6724810. PubMed ID: 32215176
    [Abstract] [Full Text] [Related]

  • 19. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70.
    Zhang D, Li J, Costa M, Gao J, Huang C.
    Cancer Res; 2010 Jan 15; 70(2):813-23. PubMed ID: 20068160
    [Abstract] [Full Text] [Related]

  • 20. Heat shock protein 90 and prolyl hydroxylase 2 co-regulate hypoxia-inducible factor-1α expression in porcine small intestinal epithelial cells under heat stress.
    Liu Y, Fan G, Zhang G, Xiong Y, Li H.
    J Therm Biol; 2024 May 15; 122():103881. PubMed ID: 38870755
    [Abstract] [Full Text] [Related]

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