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164 related items for PubMed ID: 31489665

  • 1. Antitumor activity of alantolactone in lung cancer cell lines NCI-H1299 and Anip973.
    Liu J, Yang Z, Kong Y, He Y, Xu Y, Cao X.
    J Food Biochem; 2019 Sep; 43(9):e12972. PubMed ID: 31489665
    [Abstract] [Full Text] [Related]

  • 2. Apoptosis-promoting and migration-suppressing effect of alantolactone on gastric cancer cell lines BGC-823 and SGC-7901 via regulating p38MAPK and NF-κB pathways.
    He Y, Cao X, Kong Y, Wang S, Xia Y, Bi R, Liu J.
    Hum Exp Toxicol; 2019 Oct; 38(10):1132-1144. PubMed ID: 31203647
    [Abstract] [Full Text] [Related]

  • 3. Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway.
    Cui L, Bu W, Song J, Feng L, Xu T, Liu D, Ding W, Wang J, Li C, Ma B, Luo Y, Jiang Z, Wang C, Chen J, Hou J, Yan H, Yang L, Jia X.
    Arch Pharm Res; 2018 Mar; 41(3):299-313. PubMed ID: 29214600
    [Abstract] [Full Text] [Related]

  • 4. Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
    He W, Cao P, Xia Y, Hong L, Zhang T, Shen X, Zheng P, Shen H, Zhao Y, Zou P.
    Free Radic Res; 2019 Jan; 53(1):104-114. PubMed ID: 30668191
    [Abstract] [Full Text] [Related]

  • 5. Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells.
    Ding Y, Wang H, Niu J, Luo M, Gou Y, Miao L, Zou Z, Cheng Y.
    Int J Mol Sci; 2016 Apr 14; 17(4):558. PubMed ID: 27089328
    [Abstract] [Full Text] [Related]

  • 6. Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells.
    Chun J, Choi RJ, Khan S, Lee DS, Kim YC, Nam YJ, Lee DU, Kim YS.
    Int Immunopharmacol; 2012 Dec 14; 14(4):375-83. PubMed ID: 22940184
    [Abstract] [Full Text] [Related]

  • 7. Sesquiterpene Lactones Containing an α-Methylene-γ-Lactone Moiety Selectively Down-Regulate the Expression of Tumor Necrosis Factor Receptor 1 by Promoting Its Ectodomain Shedding in Human Lung Adenocarcinoma A549 Cells.
    Vu QV, Sayama S, Ando M, Kataoka T.
    Molecules; 2024 Apr 19; 29(8):. PubMed ID: 38675685
    [Abstract] [Full Text] [Related]

  • 8. Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells.
    Yan YY, Zhang Q, Zhang B, Yang B, Lin NM.
    Nat Prod Res; 2020 Sep 19; 34(17):2539-2544. PubMed ID: 30661396
    [Abstract] [Full Text] [Related]

  • 9. Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
    He R, Shi X, Zhou M, Zhao Y, Pan S, Zhao C, Guo X, Wang M, Li X, Qin R.
    Toxicol Appl Pharmacol; 2018 Oct 01; 356():159-171. PubMed ID: 30086361
    [Abstract] [Full Text] [Related]

  • 10. Alantolactone exhibits antiproliferative and apoptosis-promoting properties in colon cancer model via activation of the MAPK-JNK/c-Jun signaling pathway.
    Ren Y, Lv C, Zhang J, Zhang B, Yue B, Luo X, Yu Z, Wang H, Ren J, Wang Z, Dou W.
    Mol Cell Biochem; 2021 Dec 01; 476(12):4387-4403. PubMed ID: 34460036
    [Abstract] [Full Text] [Related]

  • 11. Alantolactone Induces Apoptosis and Cell Cycle Arrest on Lung Squamous Cancer SK-MES-1 Cells.
    Zhao P, Pan Z, Luo Y, Zhang L, Li X, Zhang G, Zhang Y, Cui R, Sun M, Zhang X.
    J Biochem Mol Toxicol; 2015 May 01; 29(5):199-206. PubMed ID: 25597476
    [Abstract] [Full Text] [Related]

  • 12. Semisynthesis, an Anti-Inflammatory Effect of Derivatives of 1β-Hydroxy Alantolactone from Inula britannica.
    Chen L, Zhang JP, Liu X, Tang JJ, Xiang P, Ma XM.
    Molecules; 2017 Oct 27; 22(11):. PubMed ID: 29077042
    [Abstract] [Full Text] [Related]

  • 13. Alantolactone: A sesquiterpene lactone with diverse pharmacological effects.
    Liu X, Bian L, Duan X, Zhuang X, Sui Y, Yang L.
    Chem Biol Drug Des; 2021 Dec 27; 98(6):1131-1145. PubMed ID: 34624172
    [Abstract] [Full Text] [Related]

  • 14. Alantolactone induces apoptosis and suppresses migration in MCF‑7 human breast cancer cells via the p38 MAPK, NF‑κB and Nrf2 signaling pathways.
    Liu J, Liu M, Wang S, He Y, Huo Y, Yang Z, Cao X.
    Int J Mol Med; 2018 Oct 27; 42(4):1847-1856. PubMed ID: 30015828
    [Abstract] [Full Text] [Related]

  • 15. Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway.
    Wang J, Zhang Y, Liu X, Wang J, Li B, Liu Y, Wang J.
    Int J Mol Med; 2019 Sep 27; 44(3):1026-1038. PubMed ID: 31524219
    [Abstract] [Full Text] [Related]

  • 16. Alantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades.
    Wang X, Yu Z, Wang C, Cheng W, Tian X, Huo X, Wang Y, Sun C, Feng L, Xing J, Lan Y, Sun D, Hou Q, Zhang B, Ma X, Zhang B.
    J Exp Clin Cancer Res; 2017 Jul 12; 36(1):93. PubMed ID: 28701209
    [Abstract] [Full Text] [Related]

  • 17. Alantolactone induces apoptosis in RKO cells through the generation of reactive oxygen species and the mitochondrial pathway.
    Zhang Y, Bao YL, Wu Y, Yu CL, Huang YX, Sun Y, Zheng LH, Li YX.
    Mol Med Rep; 2013 Oct 12; 8(4):967-72. PubMed ID: 23970102
    [Abstract] [Full Text] [Related]

  • 18. A comprehensive review of anticancer mechanisms of action of Alantolactone.
    Babaei G, Gholizadeh-Ghaleh Aziz S, Rajabi Bazl M, Khadem Ansari MH.
    Biomed Pharmacother; 2021 Apr 12; 136():111231. PubMed ID: 33454597
    [Abstract] [Full Text] [Related]

  • 19. Alantolactone facilitates ferroptosis in non-small cell lung cancer through promoting FTH1 ubiquitination and degradation.
    Huang Y, Xiang P, Chen Y, Pan Q, Yuan K.
    Chem Biol Drug Des; 2024 Aug 12; 104(2):e14560. PubMed ID: 39175059
    [Abstract] [Full Text] [Related]

  • 20. Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction.
    Khan M, Yi F, Rasul A, Li T, Wang N, Gao H, Gao R, Ma T.
    IUBMB Life; 2012 Sep 12; 64(9):783-94. PubMed ID: 22837216
    [Abstract] [Full Text] [Related]

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