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Journal Abstract Search

845 related items for PubMed ID: 31499359

  • 1. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 2. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 20; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 5. Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production.
    Tang H, Liang Y, Cheng J, Ding K, Wang Y.
    Eur J Med Chem; 2021 Oct 05; 221():113531. PubMed ID: 34044345
    [Abstract] [Full Text] [Related]

  • 6. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 01; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 11. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 01; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 13. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and biological evaluation of 1-substituted -2-aryl imidazoles targeting tubulin polymerization as potential anticancer agents.
    Li L, Quan D, Chen J, Ding J, Zhao J, Lv L, Chen J.
    Eur J Med Chem; 2019 Dec 15; 184():111732. PubMed ID: 31610372
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
    Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y.
    Bioorg Chem; 2021 Oct 13; 115():105239. PubMed ID: 34399321
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.
    Sun L, Wang C, Hu X, Wu Y, Jiang Z, Li Z, Chen X, Hu L.
    Bioorg Chem; 2020 Jun 13; 99():103766. PubMed ID: 32247110
    [Abstract] [Full Text] [Related]

  • 18. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
    Romagnoli R, Oliva P, Salvador MK, Manfredini S, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2021 Mar 15; 214():113229. PubMed ID: 33550186
    [Abstract] [Full Text] [Related]

  • 19. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J.
    Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231
    [Abstract] [Full Text] [Related]

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