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Journal Abstract Search

310 related items for PubMed ID: 31499589

  • 1. LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.
    Liu Z, Wang H, Guan L, Lai C, Yu W, Lai M.
    Br J Pharmacol; 2020 Jan; 177(2):298-313. PubMed ID: 31499589
    [Abstract] [Full Text] [Related]

  • 2. LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis.
    Wang H, Liu Z, Guan L, Li J, Chen S, Yu W, Lai M.
    Pharmacol Res; 2020 Mar; 153():104661. PubMed ID: 31982491
    [Abstract] [Full Text] [Related]

  • 3. Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer.
    Zhang ZH, Li MY, Wang Z, Zuo HX, Wang JY, Xing Y, Jin C, Xu G, Piao L, Piao H, Ma J, Jin X.
    Phytomedicine; 2020 Mar; 68():153172. PubMed ID: 32004989
    [Abstract] [Full Text] [Related]

  • 4. LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer.
    Pan L, Chen X, Fu S, Yu W, Li C, Wang T, Lo HW, Lin J.
    Breast Cancer Res Treat; 2020 May; 181(1):31-41. PubMed ID: 32240456
    [Abstract] [Full Text] [Related]

  • 5. Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer.
    Fan LC, Teng HW, Shiau CW, Tai WT, Hung MH, Yang SH, Jiang JK, Chen KF.
    Oncotarget; 2016 Sep 27; 7(39):64136-64147. PubMed ID: 27580057
    [Abstract] [Full Text] [Related]

  • 6. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.
    Zhang L, Liu P, Jiang Y, Fan D, He X, Zhang J, Luo B, Sui J, Luo Y, Fu X, Yang T.
    Eur J Med Chem; 2024 Jun 05; 272():116448. PubMed ID: 38704936
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  • 10. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q, Zhong Y, Li B, Ouyang S, Deng L, Mo J, Shi S, Lv N, Wu R, Liu P, Hu W, Zhang X, Wang Y.
    Eur J Med Chem; 2021 Oct 05; 221():113525. PubMed ID: 34000483
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  • 11. Fraxetin inhibits the growth of colon adenocarcinoma cells via the Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway.
    Ren S, Xing Y, Wang C, Jiang F, Liu G, Li Z, Jiang T, Zhu Y, Piao D.
    Int J Biochem Cell Biol; 2020 Aug 05; 125():105777. PubMed ID: 32504672
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  • 12. Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO-1701.
    Nishisaka F, Taniguchi K, Tsugane M, Hirata G, Takagi A, Asakawa N, Kurita A, Takahashi H, Ogo N, Shishido Y, Asai A.
    Cancer Sci; 2020 May 05; 111(5):1774-1784. PubMed ID: 32112605
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  • 14. Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3Tyr705 phosphorylation.
    Sun X, Xu Q, Zeng L, Xie L, Zhao Q, Xu H, Wang X, Jiang N, Fu P, Sang M.
    Cancer Med; 2020 Nov 05; 9(22):8685-8700. PubMed ID: 33040485
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  • 16. Design, Synthesis, And Evaluation Of Cyanopyridines As Anti-Colorectal Cancer Agents Via Inhibiting STAT3 Pathway.
    Xu L, Shi L, Qiu S, Chen S, Lin M, Xiang Y, Zhao C, Zhu J, Shen L, Zuo Z.
    Drug Des Devel Ther; 2019 Nov 05; 13():3369-3381. PubMed ID: 31576111
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  • 17. Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
    Li M, Yue GG, Song LH, Huang MB, Lee JK, Tsui SK, Fung KP, Tan NH, Lau CB.
    Biochem Pharmacol; 2018 Apr 05; 150():191-201. PubMed ID: 29454618
    [Abstract] [Full Text] [Related]

  • 18. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design.
    Yu W, Xiao H, Lin J, Li C.
    J Med Chem; 2013 Jun 13; 56(11):4402-12. PubMed ID: 23651330
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  • 19. Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting STAT3.
    Fan D, Liu P, Li Z, He X, Zhang L, Jiang W, Ang W, Yang T.
    Bioorg Chem; 2024 Sep 13; 150():107565. PubMed ID: 38905884
    [Abstract] [Full Text] [Related]

  • 20. Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth.
    Li X, Ma H, Li L, Chen Y, Sun X, Dong Z, Liu JY, Zhu W, Zhang JT.
    Oncogene; 2018 May 13; 37(18):2469-2480. PubMed ID: 29456240
    [Abstract] [Full Text] [Related]

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