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264 related items for PubMed ID: 31515143

  • 1. Intranasal nanoemulsion-adjuvanted HSV-2 subunit vaccine is effective as a prophylactic and therapeutic vaccine using the guinea pig model of genital herpes.
    Bernstein DI, Cardin RD, Bravo FJ, Hamouda T, Pullum DA, Cohen G, Bitko V, Fattom A.
    Vaccine; 2019 Oct 08; 37(43):6470-6477. PubMed ID: 31515143
    [Abstract] [Full Text] [Related]

  • 2. A Dual-Modality Herpes Simplex Virus 2 Vaccine for Preventing Genital Herpes by Using Glycoprotein C and D Subunit Antigens To Induce Potent Antibody Responses and Adenovirus Vectors Containing Capsid and Tegument Proteins as T Cell Immunogens.
    Awasthi S, Mahairas GG, Shaw CE, Huang ML, Koelle DM, Posavad C, Corey L, Friedman HM.
    J Virol; 2015 Aug 08; 89(16):8497-509. PubMed ID: 26041292
    [Abstract] [Full Text] [Related]

  • 3. The HSV-1 live attenuated VC2 vaccine provides protection against HSV-2 genital infection in the guinea pig model of genital herpes.
    Bernstein DI, Pullum DA, Cardin RD, Bravo FJ, Dixon DA, Kousoulas KG.
    Vaccine; 2019 Jan 03; 37(1):61-68. PubMed ID: 30471955
    [Abstract] [Full Text] [Related]

  • 4. Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Reservoir.
    Hensel MT, Marshall JD, Dorwart MR, Heeke DS, Rao E, Tummala P, Yu L, Cohen GH, Eisenberg RJ, Sloan DD.
    J Virol; 2017 May 01; 91(9):. PubMed ID: 28228587
    [Abstract] [Full Text] [Related]

  • 5. Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig.
    Bernstein DI, Earwood JD, Bravo FJ, Cohen GH, Eisenberg RJ, Clark JR, Fairman J, Cardin RD.
    Vaccine; 2011 Mar 03; 29(11):2071-8. PubMed ID: 21238569
    [Abstract] [Full Text] [Related]

  • 6. Blocking herpes simplex virus 2 glycoprotein E immune evasion as an approach to enhance efficacy of a trivalent subunit antigen vaccine for genital herpes.
    Awasthi S, Huang J, Shaw C, Friedman HM.
    J Virol; 2014 Aug 03; 88(15):8421-32. PubMed ID: 24829358
    [Abstract] [Full Text] [Related]

  • 7. Immunogenicity and efficacy of intramuscular replication-defective and subunit vaccines against herpes simplex virus type 2 in the mouse genital model.
    Delagrave S, Hernandez H, Zhou C, Hamberger JF, Mundle ST, Catalan J, Baloglu S, Anderson SF, DiNapoli JM, Londoño-Hayes P, Parrington M, Almond J, Kleanthous H.
    PLoS One; 2012 Aug 03; 7(10):e46714. PubMed ID: 23071620
    [Abstract] [Full Text] [Related]

  • 8. Cross protective efficacy of the Non-Neurotropic live attenuated herpes simplex virus type 1 vaccine VC-2 is enhanced by intradermal vaccination and deletion of glycoprotein G.
    Stanfield BA, Bravo FJ, Dixon DA, Chouljenko VN, Kousoulas KG, Bernstein DI.
    Vaccine; 2022 Oct 06; 40(42):6093-6099. PubMed ID: 36114130
    [Abstract] [Full Text] [Related]

  • 9. Duration of protection from live attenuated vs. sub unit HSV-2 vaccines in the guinea pig model of genital herpes: Reassessing efficacy using endpoints from clinical trials.
    Bernstein DI, Cardin RD, Pullum DA, Bravo FJ, Kousoulas KG, Dixon DA.
    PLoS One; 2019 Oct 06; 14(3):e0213401. PubMed ID: 30917165
    [Abstract] [Full Text] [Related]

  • 10. The adjuvant CLDC increases protection of a herpes simplex type 2 glycoprotein D vaccine in guinea pigs.
    Bernstein DI, Farley N, Bravo FJ, Earwood J, McNeal M, Fairman J, Cardin R.
    Vaccine; 2010 May 07; 28(21):3748-53. PubMed ID: 19857450
    [Abstract] [Full Text] [Related]

  • 11. A trivalent subunit antigen glycoprotein vaccine as immunotherapy for genital herpes in the guinea pig genital infection model.
    Awasthi S, Hook LM, Shaw CE, Friedman HM.
    Hum Vaccin Immunother; 2017 Dec 02; 13(12):2785-2793. PubMed ID: 28481687
    [Abstract] [Full Text] [Related]

  • 12. A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2.
    Bernstein DI, Morello CS, Cardin RD, Bravo FJ, Kraynyak KA, Spector DH.
    Vaccine; 2020 Jan 03; 38(1):79-89. PubMed ID: 31611098
    [Abstract] [Full Text] [Related]

  • 13. Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4+ and CD8+ TRM Cells Associated with Protection against Recurrent Genital Herpes.
    Srivastava R, Roy S, Coulon PG, Vahed H, Prakash S, Dhanushkodi N, Kim GJ, Fouladi MA, Campo J, Teng AA, Liang X, Schaefer H, BenMohamed L.
    J Virol; 2019 May 01; 93(9):. PubMed ID: 30787156
    [Abstract] [Full Text] [Related]

  • 14. Protection provided by a herpes simplex virus 2 (HSV-2) glycoprotein C and D subunit antigen vaccine against genital HSV-2 infection in HSV-1-seropositive guinea pigs.
    Awasthi S, Balliet JW, Flynn JA, Lubinski JM, Shaw CE, DiStefano DJ, Cai M, Brown M, Smith JF, Kowalski R, Swoyer R, Galli J, Copeland V, Rios S, Davidson RC, Salnikova M, Kingsley S, Bryan J, Casimiro DR, Friedman HM.
    J Virol; 2014 Feb 01; 88(4):2000-10. PubMed ID: 24284325
    [Abstract] [Full Text] [Related]

  • 15. A herpes simplex virus 2 (HSV-2) glycoprotein D-expressing nonreplicating dominant-negative HSV-2 virus vaccine is superior to a gD2 subunit vaccine against HSV-2 genital infection in guinea pigs.
    Zhang P, Xie L, Balliet JW, Casimiro DR, Yao F.
    PLoS One; 2014 Feb 01; 9(6):e101373. PubMed ID: 24979708
    [Abstract] [Full Text] [Related]

  • 16. Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs.
    Hook LM, Cairns TM, Awasthi S, Brooks BD, Ditto NT, Eisenberg RJ, Cohen GH, Friedman HM.
    PLoS Pathog; 2018 May 01; 14(5):e1007095. PubMed ID: 29791513
    [Abstract] [Full Text] [Related]

  • 17. Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
    Hoshino Y, Pesnicak L, Dowdell KC, Burbelo PD, Knipe DM, Straus SE, Cohen JI.
    J Infect Dis; 2009 Oct 01; 200(7):1088-95. PubMed ID: 19702506
    [Abstract] [Full Text] [Related]

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  • 20. Immunogenicity, protective efficacy, and non-replicative status of the HSV-2 vaccine candidate HSV529 in mice and guinea pigs.
    Bernard MC, Barban V, Pradezynski F, de Montfort A, Ryall R, Caillet C, Londono-Hayes P.
    PLoS One; 2015 Oct 01; 10(4):e0121518. PubMed ID: 25837802
    [Abstract] [Full Text] [Related]

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