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317 related items for PubMed ID: 31531187

  • 1. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
    Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z.
    Oxid Med Cell Longev; 2019; 2019():8781690. PubMed ID: 31531187
    [Abstract] [Full Text] [Related]

  • 2. Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78.
    Cai Y, Zheng Y, Gu J, Wang S, Wang N, Yang B, Zhang F, Wang D, Fu W, Wang Z.
    Cell Death Dis; 2018 May 25; 9(6):636. PubMed ID: 29802332
    [Abstract] [Full Text] [Related]

  • 3. Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
    Jiao L, Wang S, Zheng Y, Wang N, Yang B, Wang D, Yang D, Mei W, Zhao Z, Wang Z.
    Biochem Pharmacol; 2019 Mar 25; 161():149-162. PubMed ID: 30684465
    [Abstract] [Full Text] [Related]

  • 4. Betulinic acid induces apoptosis of HeLa cells via ROS-dependent ER stress and autophagy in vitro and in vivo.
    Chen P, Zhang X, Fang Q, Zhao Z, Lin C, Zhou Y, Liu F, Zhu C, Wu A.
    J Nat Med; 2024 Jun 25; 78(3):677-692. PubMed ID: 38403724
    [Abstract] [Full Text] [Related]

  • 5. Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells.
    Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Deregowska A, Wnuk M.
    Apoptosis; 2017 Jun 25; 22(6):800-815. PubMed ID: 28213701
    [Abstract] [Full Text] [Related]

  • 6. Betulinic acid attenuates T-2 toxin-induced cytotoxicity in porcine kidney cells by blocking oxidative stress and endoplasmic reticulum stress.
    Li X, Wang X, Liu S, Wang J, Liu X, Zhu Y, Zhang L, Li R.
    Comp Biochem Physiol C Toxicol Pharmacol; 2021 Nov 25; 249():109124. PubMed ID: 34224893
    [Abstract] [Full Text] [Related]

  • 7. CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells.
    Clarke WR, Amundadottir L, James MA.
    Int J Cancer; 2019 Mar 15; 144(6):1367-1378. PubMed ID: 30468251
    [Abstract] [Full Text] [Related]

  • 8. Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
    Zhou H, Zhang Y, Fu Y, Chan L, Lee AS.
    J Biol Chem; 2011 Jul 22; 286(29):25687-96. PubMed ID: 21622563
    [Abstract] [Full Text] [Related]

  • 9. Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
    Wu J, Wu Y, Lian X.
    Biol Open; 2020 Nov 12; 9(11):. PubMed ID: 33115703
    [Abstract] [Full Text] [Related]

  • 10. Asperuloside exhibits a novel anti-leukemic activity by triggering ER stress-regulated apoptosis via targeting GRP78.
    Rong C, Wei W, Yu-Hong T.
    Biomed Pharmacother; 2020 May 12; 125():109819. PubMed ID: 32106370
    [Abstract] [Full Text] [Related]

  • 11. Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: role of Sp transcription factors and microRNA-27a:ZBTB10.
    Mertens-Talcott SU, Noratto GD, Li X, Angel-Morales G, Bertoldi MC, Safe S.
    Mol Carcinog; 2013 Aug 12; 52(8):591-602. PubMed ID: 22407812
    [Abstract] [Full Text] [Related]

  • 12. The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.
    Samanta S, Yang S, Debnath B, Xue D, Kuang Y, Ramkumar K, Lee AS, Ljungman M, Neamati N.
    Cancer Res; 2021 Apr 01; 81(7):1883-1895. PubMed ID: 33531374
    [Abstract] [Full Text] [Related]

  • 13. Suppression of endoplasmic reticulum stress-associated pathways and hepatocyte apoptosis participates in the attenuation of betulinic acid on alcohol-provoked liver injury in mice.
    He E, Ma Y, Kong L, Huang Y, Huang C, Yang W, Yi J, Zhu L.
    Food Funct; 2022 Nov 14; 13(22):11489-11502. PubMed ID: 36190121
    [Abstract] [Full Text] [Related]

  • 14. Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
    Gu M, Zhao P, Zhang S, Fan S, Yang L, Tong Q, Ji G, Huang C.
    Br J Pharmacol; 2019 Apr 14; 176(7):847-863. PubMed ID: 30635917
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway.
    Han KS, Li N, Raven PA, Fazli L, Frees S, Ettinger S, Park KC, Hong SJ, Gleave ME, So AI.
    Oncotarget; 2015 Oct 27; 6(33):34818-30. PubMed ID: 26472187
    [Abstract] [Full Text] [Related]

  • 16. Recruitment of USP10 by GCS1 to deubiquitinate GRP78 promotes the progression of colorectal cancer via alleviating endoplasmic reticulum stress.
    Chen Y, Shen H, Wang Z, Huang C, Zhang H, Shao Y, Tong Y, Xu L, Lu Y, Fu Z.
    J Exp Clin Cancer Res; 2024 Sep 13; 43(1):261. PubMed ID: 39267084
    [Abstract] [Full Text] [Related]

  • 17. GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
    Fu Y, Li J, Lee AS.
    Cancer Res; 2007 Apr 15; 67(8):3734-40. PubMed ID: 17440086
    [Abstract] [Full Text] [Related]

  • 18. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells.
    Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa DS, Esposito F, Landriscina M.
    Int J Oncol; 2014 Feb 15; 44(2):573-82. PubMed ID: 24297638
    [Abstract] [Full Text] [Related]

  • 19. Cell Surface GRP78 Accelerated Breast Cancer Cell Proliferation and Migration by Activating STAT3.
    Yao X, Liu H, Zhang X, Zhang L, Li X, Wang C, Sun S.
    PLoS One; 2015 Feb 15; 10(5):e0125634. PubMed ID: 25973748
    [Abstract] [Full Text] [Related]

  • 20. Betulinic Acid Inhibits the Stemness of Gastric Cancer Cells by Regulating the GRP78-TGF-β1 Signaling Pathway and Macrophage Polarization.
    Chen JL, Tai YS, Tsai HY, Hsieh CY, Chen CL, Liu CJ, Wu DC, Huang YB, Lin MW.
    Molecules; 2023 Feb 11; 28(4):. PubMed ID: 36838713
    [Abstract] [Full Text] [Related]

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