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406 related items for PubMed ID: 31534165

  • 1. ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation.
    Peñaranda-Fajardo NM, Meijer C, Liang Y, Dijkstra BM, Aguirre-Gamboa R, den Dunnen WFA, Kruyt FAE.
    Cell Death Dis; 2019 Sep 18; 10(10):690. PubMed ID: 31534165
    [Abstract] [Full Text] [Related]

  • 2. GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death.
    Liu G, Yu J, Wu R, Shi L, Zhang X, Zhang W, Zhong X, Wang Y, Li H, Shen Y, Wu C, Yu R, Niu M, Liu X.
    Cell Death Dis; 2021 Jul 23; 12(8):733. PubMed ID: 34301924
    [Abstract] [Full Text] [Related]

  • 3. A Sox2:miR-486-5p Axis Regulates Survival of GBM Cells by Inhibiting Tumor Suppressor Networks.
    Lopez-Bertoni H, Kotchetkov IS, Mihelson N, Lal B, Rui Y, Ames H, Lugo-Fagundo M, Guerrero-Cazares H, Quiñones-Hinojosa A, Green JJ, Laterra J.
    Cancer Res; 2020 Apr 15; 80(8):1644-1655. PubMed ID: 32094299
    [Abstract] [Full Text] [Related]

  • 4. The endoplasmic reticulum stress/unfolded protein response in gliomagenesis, tumor progression and as a therapeutic target in glioblastoma.
    Peñaranda Fajardo NM, Meijer C, Kruyt FA.
    Biochem Pharmacol; 2016 Oct 15; 118():1-8. PubMed ID: 27106078
    [Abstract] [Full Text] [Related]

  • 5. Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation.
    Berezovsky AD, Poisson LM, Cherba D, Webb CP, Transou AD, Lemke NW, Hong X, Hasselbach LA, Irtenkauf SM, Mikkelsen T, deCarvalho AC.
    Neoplasia; 2014 Mar 15; 16(3):193-206, 206.e19-25. PubMed ID: 24726753
    [Abstract] [Full Text] [Related]

  • 6. PERK Regulates Glioblastoma Sensitivity to ER Stress Although Promoting Radiation Resistance.
    Dadey DYA, Kapoor V, Khudanyan A, Thotala D, Hallahan DE.
    Mol Cancer Res; 2018 Oct 15; 16(10):1447-1453. PubMed ID: 29991528
    [Abstract] [Full Text] [Related]

  • 7. Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome.
    Binder ZA, Siu IM, Eberhart CG, Ap Rhys C, Bai RY, Staedtke V, Zhang H, Smoll NR, Piantadosi S, Piccirillo SG, Dimeco F, Weingart JD, Vescovi A, Olivi A, Riggins GJ, Gallia GL.
    PLoS One; 2013 Oct 15; 8(10):e75945. PubMed ID: 24146797
    [Abstract] [Full Text] [Related]

  • 8. Sox2, a stemness gene, regulates tumor-initiating and drug-resistant properties in CD133-positive glioblastoma stem cells.
    Song WS, Yang YP, Huang CS, Lu KH, Liu WH, Wu WW, Lee YY, Lo WL, Lee SD, Chen YW, Huang PI, Chen MT.
    J Chin Med Assoc; 2016 Oct 15; 79(10):538-45. PubMed ID: 27530866
    [Abstract] [Full Text] [Related]

  • 9. miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.
    Luo W, Yan D, Song Z, Zhu X, Liu X, Li X, Zhao S.
    Life Sci; 2019 Jun 01; 226():98-106. PubMed ID: 30980849
    [Abstract] [Full Text] [Related]

  • 10. The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target.
    Li YH, Tardif G, Hum D, Kapoor M, Fahmi H, Pelletier JP, Martel-Pelletier J.
    Arthritis Res Ther; 2016 Jul 19; 18():172. PubMed ID: 27435272
    [Abstract] [Full Text] [Related]

  • 11. Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy.
    Vandewynckel YP, Laukens D, Bogaerts E, Paridaens A, Van den Bussche A, Verhelst X, Van Steenkiste C, Descamps B, Vanhove C, Libbrecht L, De Rycke R, Lambrecht BN, Geerts A, Janssens S, Van Vlierberghe H.
    Hepatol Int; 2015 Jan 19; 9(1):93-104. PubMed ID: 25598862
    [Abstract] [Full Text] [Related]

  • 12. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
    Dastghaib S, Shojaei S, Mostafavi-Pour Z, Sharma P, Patterson JB, Samali A, Mokarram P, Ghavami S.
    Cells; 2020 Oct 22; 9(11):. PubMed ID: 33105603
    [Abstract] [Full Text] [Related]

  • 13. Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance.
    Visvanathan A, Patil V, Arora A, Hegde AS, Arivazhagan A, Santosh V, Somasundaram K.
    Oncogene; 2018 Jan 25; 37(4):522-533. PubMed ID: 28991227
    [Abstract] [Full Text] [Related]

  • 14. FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.
    Lee Y, Kim KH, Kim DG, Cho HJ, Kim Y, Rheey J, Shin K, Seo YJ, Choi YS, Lee JI, Lee J, Joo KM, Nam DH.
    PLoS One; 2015 Jan 25; 10(10):e0137703. PubMed ID: 26444992
    [Abstract] [Full Text] [Related]

  • 15. A curcumin derivative hydrazinobenzoylcurcumin suppresses stem-like features of glioblastoma cells by targeting Ca2+ /calmodulin-dependent protein kinase II.
    Shin HJ, Lee S, Jung HJ.
    J Cell Biochem; 2019 Apr 25; 120(4):6741-6752. PubMed ID: 30390339
    [Abstract] [Full Text] [Related]

  • 16. Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma.
    Soroceanu L, Matlaf L, Khan S, Akhavan A, Singer E, Bezrookove V, Decker S, Ghanny S, Hadaczek P, Bengtsson H, Ohlfest J, Luciani-Torres MG, Harkins L, Perry A, Guo H, Soteropoulos P, Cobbs CS.
    Cancer Res; 2015 Aug 01; 75(15):3065-76. PubMed ID: 26239477
    [Abstract] [Full Text] [Related]

  • 17. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.
    Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD.
    Neuro Oncol; 2012 Feb 01; 14(2):132-44. PubMed ID: 22067563
    [Abstract] [Full Text] [Related]

  • 18. PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells.
    Sheshadri N, Poria DK, Sharan S, Hu Y, Yan C, Koparde VN, Balamurugan K, Sterneck E.
    Cell Death Dis; 2021 Nov 01; 12(11):1038. PubMed ID: 34725321
    [Abstract] [Full Text] [Related]

  • 19. Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress.
    Chou CK, Liu W, Hong YJ, Dahms HU, Chiu CH, Chang WT, Chien CM, Yen CH, Cheng YB, Chiu CC.
    Int J Mol Sci; 2018 Jun 21; 19(7):. PubMed ID: 29933620
    [Abstract] [Full Text] [Related]

  • 20. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.
    Biochem Pharmacol; 2016 Jun 01; 109():27-47. PubMed ID: 27059255
    [Abstract] [Full Text] [Related]

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